Rchr
J-GLOBAL ID:201201093280801544   Update date: Jan. 30, 2024

Shimizu Takashi

シミズ タケシ | Shimizu Takashi
Affiliation and department:
Research field  (3): Clinical pharmacy ,  Physiology ,  Neuroscience - general
Research keywords  (16): 幹細胞 ,  メカノバイオロジー ,  GSK3β ,  神経前駆細胞 ,  β-catenin ,  分化 ,  細胞分裂 ,  増殖 ,  神経分化 ,  oligodendrocyte ,  Wnt ,  glia ,  未分化性維持 ,  神経幹細胞 ,  細胞増殖 ,  myelin
Research theme for competitive and other funds  (8):
  • 2021 - 2024 オリゴデンドロサイトの力覚機構の解析と白質障害治療研究への応用
  • 2018 - 2022 Analysis of the recovery mechanism of cell therapy to perinatal white matter injury
  • 2015 - 2018 Project to create international glial researcher network: mainly focusing on Japan-Germany research exchange
  • 2013 - 2018 Studies on communication between neuroaxons via oligodendrocytes.
  • 2016 - 2018 メカニカルストレスの生理的機能の解析
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Papers (27):
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MISC (16):
  • YAP functions as a mechanotransducer in oligodendrocyte morphogenesis and maturation. 2017. 89. 4. 559-563
  • K. Kunisawa, T. Shimizu, Y. Osanai, K. Kobayashi, A. Hayashi, H. Baba, M. A. Bhat, K. Ikenaka. Analysis of neuronal responses against disruption of neuro-glial interaction and its effect on brain functions. JOURNAL OF NEUROCHEMISTRY. 2015. 134. 286-286
  • Roles of GSK3beta signaling in the self-renewal of neural progenitor cells. 2014. 86. 1. 68-71
  • 備前 典久, 井上 俊洋, 清水 健史, 鹿川 哲史, 田賀 哲也. 神経幹/前駆細胞における細胞周期調節因子cyclin D1は細胞周期非依存的にアストロサイト分化を阻害する(Cyclin D1 inhibits astrocyte differentiation from neural stem/progenitor cells in a manner independent of cell cycle progression). 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2010. 83回・33回. 3P-0876
  • Norihisa Bizen, Takeshi Shimizu, Toshihiro Inoue, Tetsushi Kagawa, Tetsuya Taga. Cross-talk between growth and differentiation pathways in cell fate determination in the developing brain. DIFFERENTIATION. 2010. 80. S8-S8
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Books (2):
  • オリゴデンドロサイト-軸索相互作用による脳機能発現
    実験医学 第4章6 169-174 2019
  • 神経系の分化、形成、再生
    分子生物学イラストレイテッド 改訂第3版 269-275
Lectures and oral presentations  (4):
  • Investigation of a novel mechanism underlying neuronal subtype-dependent myelination
    (2021)
  • Mechanical control of oligodendrocyte morphogenesis and maturation by mechanosensors
    (2018)
  • Roles of oligodendrocyte-neuron interactions in myelination
    (2017)
  • Microglia-induced activation of non-canonical Wnt signaling aggravates neurodegeneration in demyelinating disorders
    (APSN, 14th Meeting of the Asian-Pacific Society for Neurochemistry 2016)
Education (3):
  • 2000 - 2003 The Graduate University for Advanced Studies School of Life Science Department of Physiological Sciences
  • 1998 - 2000 Osaka University
  • 1994 - 1998 Osaka University School of Engineering Science Direct Affiliates
Professional career (1):
  • 博士 (理学)
Work history (6):
  • 2023/04 - 現在 Shokei University
  • 2017/08 - 2023/03 Nagoya City University
  • 2012/04 - 2017/07 生理学研究所 助教
  • 2010/04 - 2012/03 National University of Singapore Mechanobiology Institute postdoctoral fellow
  • 2008/02 - 2010/03 理化学研究所 発生・再生科学総合研究センター 体軸形成研究チーム 研究員
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Association Membership(s) (3):
THE PHYSIOLOGICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPAN NEUROSCIENCE SOCIETY
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