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J-GLOBAL ID：201302237560173177   Reference number：13A0088285

Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation

肝細胞癌細胞増殖に対するファルネソイドX受容体の重要な役割

Author (18)： FUJINO Tomofumi (Tokyo Univ. Pharmacy and Life Sci.) ,  TAKEUCHI Airi (Tokyo Univ. Pharmacy and Life Sci.) ,  MARUKO-OHTAKE Akiko (Tohoku Pharmaceutical Univ.) ,  OHTAKE Yosuke (Tohoku Pharmaceutical Univ.) ,  SATOH Junichi (Tokyo Univ. Pharmacy and Life Sci.) ,  KOBAYASHI Tomonori (Tohoku Pharmaceutical Univ.) ,  TANAKA Toshiaki (Tokyo Inst. of Technol.) ,  ITO Haruka (Tokyo Univ. Pharmacy and Life Sci.) ,  ITO Haruka (National Inst. of Health Sci.) ,  SAKAMAKI Ryosuke (Tokyo Univ. Pharmacy and Life Sci.) ,  KASHIMURA Ryo (Tokyo Univ. Pharmacy and Life Sci.) ,  ANDO Ken (Tokyo Univ. Pharmacy and Life Sci.) ,  NISHIMAKI-MOGAMI Tomoko (National Inst. of Health Sci.) ,  OHKUBO Yasuhito (Tohoku Pharmaceutical Univ.) ,  KITAMURA Naomi (Tokyo Inst. of Technol.) ,  SATO Ryuichiro (Univ. Tokyo, JPN) ,  KIKUGAWA Kiyomi (Tokyo Univ. Pharmacy and Life Sci.) ,  HAYAKAWA Makio (Tokyo Univ. Pharmacy and Life Sci.)
Material： Journal of Biochemistry  (JB)
Volume： 152  Issue： 6  Page： 577-586  Publication year： Dec. 2012 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： Cell Proliferation ,...
Semi thesaurus term： *cytosol receptor ,...

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JST classification (4)： Receptors on cell membrane  (EF04030C) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (31)：

• CARLBERG, C. Dynamics of nuclear receptor target gene regulation. Chromosoma. 2010, 119, 479-484
• FORMAN, B. M. Identification of a nuclear receptor that is activated by farnesol metabolites. Cell. 1995, 81, 687-693
• MAKISHIMA, M. Identification of a nuclear receptor for bile acids. Science. 1999, 284, 1362-1365
• PARKS, D. J. Bile acids : natural ligands for an orphan nuclear receptor. Science. 1999, 284, 1365-1368
• WANG, H. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol. Cell. 1999, 3, 543-553

Terms in the title (4)： 肝細胞癌 ,  細胞増殖 ,  ファルネソイドX受容体 ,  役割