Rchr
J-GLOBAL ID:201401001768918109
Update date: Aug. 01, 2024
Yoshimura Tomoyuki
ヨシムラトモ ユキ | Yoshimura Tomoyuki
Affiliation and department:
Research field (2):
Pharmaceuticals - chemistry and drug development
, Synthetic organic chemistry
Research keywords (3):
asymmetric synthesis
, total synthesis of natural product
, synthetic organic chemistry
Research theme for competitive and other funds (11):
- 2024 - 2027 ortho-キノンメチドを経由する不斉反応の開発と天然物合成への展開
- 2021 - 2024 Asymmetric synthesis via aryne intermadiate with dynamic chirality
- 2017 - 2020 Enantioselective total syntheses of bioactive natural products with tetrasubstituted carbon(s) using highly reactive carbon species
- 2014 - 2019 Regioselective Molecular Transforamtion of Mutifunctionalized Molecules
- 2015 - 2018 New development of cycloaddition reactions using cyclobutanones
- 2014 - 2017 Enantioselective total syntheses of bioactive natural products via the enolate intermediate with dynamic chirality
- 2011 - 2012 Syntheses of novel amino acids and natural product derived from amino acid by using memory of chirality
- 2009 - 2012 Fine Organic Synthesis based on Catalytic Regioselective Functionalization
- 2009 - 2010 Asymmetric Total Synthesis of Bioactive Natural Products via Planar Chiral Enolate
- 2007 - 2008 Syntheses of Natural Products via Memory of Chirality
- 2006 - 2007 キラルな官能基炭素アニオン種を用いる天然物合成
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Papers (55):
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Tomoyuki Yoshimura, Ken-ichi Onda, Jun-ichi Matsuo. Asymmetric Cycloaddition Reactions of Aryne Intermediates with a Chiral Carbon-Carbon Axis: Syntheses of Axially Chiral Biaryl Compounds. Organic Letters. 2023. 25. 49. 8952-8956
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Fuka Hori, Tomoyuki Yoshimura, Jun-ichi Matsuo. Construction of Indole Skeletons through Direct Catalytic Three-Component Domino Reactions of Vinylarenes, Aldehydes, and Pronucleophiles. Synlett. 2022. 33. 15. 1519-1522
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Tomoka Dentani, Ayano Kawachi, Misaki Kato, Tomoyuki Yoshimura, Jun-ichi Matsuo. Cascade cyclization of 1,2,7,8-tetraones and total synthesis of (±)-nesteretal A. Organic Chemistry Frontiers. 2022. 9. 14. 3786-3793
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Ayumi Imayoshi, Bhatraju Vasantha Lakshmi, Yoshihiro Ueda, Tomoyuki Yoshimura, Aki Matayoshi, Takumi Furuta, Takeo Kawabata. Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy. Nature Communications. 2021. 12. 1
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Shunya Morita, Tomoyuki Yoshimura, Jun-ichi Matsuo. Intermolecular domino Michael/aldol reactions of α,β-unsaturated esters, aromatic aldehydes, and various nucleophiles promoted with a catalytic amount of a guanidine base in DMSO. Tetrahedron. 2021. 94
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MISC (57):
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木下智彦, 吉村智之, 古田巧, 川端猛夫. 不斉記憶型 N-C アシル基転移を利用した四置換炭素含有γ-ラクタムの合成. 第133日本薬学会年会,岡山. 2013
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大津寄悠, 渡邊俊英, 吉村智之, 川端猛夫. C-N 軸性不斉エノラートを経由した不斉アルドール反応のメカニズム解析. 第133日本薬学会年会,岡山. 2013
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笠松幸司, 友原啓介, 吉村智之, 川端猛夫. 短寿命 C-O 軸性不斉エノラートを経由する不斉環化の立体化学. 第133日本薬学会年会,岡山. 2013
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楊畔, 多久和正訓, 吉村智之, 川端猛夫. C-N 軸性不斉エノラートを経る連続する不斉四置換炭素を持つ高歪みβ-ラクタムの不斉合成. 第32回有機合成若手セミナー, 兵庫. 2012
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木下智彦, 吉村智之, 川端猛夫. 不斉記憶型 Dieckmann 縮合を利用した四置換炭素含有環状アミノ酸の合成. 第32回有機合成若手セミナー, 兵庫. 2012
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Lectures and oral presentations (6):
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ロリオリドのジアステレオ選択的全合成研究
(第49回反応と合成の進歩シンポジウム 2023)
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軸性不斉アライン中間体を経由する不斉反応の開発
(第48回反応と合成の進歩シンポジウム 2022)
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シクロヘプタトリエン合成法の開発
(第39回メディシナルケミストリーシンポジウム 2022)
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プロトン化により促進されるキラルエノラートの共役付加:高歪みβーラクタムの不斉合成
(第37回反応と合成の進歩シンポジウム -ライフサイエンスを志向した理論、反応及び合成ー 2011)
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キラルエノラートの分子内共役付加を利用する多置換β-ラクタムの不斉合成
(第61回日本薬学会近畿支部総会・大会 2011)
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Education (3):
- 2001 - 2005 The University of Tokushima
- 1999 - 2001 The University of Tokushima
- 1995 - 1999 The University of Tokushima Faculty of Pharmaceutical Sciences
Professional career (1):
Work history (5):
- 2024/04 - 現在 International University of Health and Welfare School of Pharmacy at Narita, Department of Pharmaceutical Sciences at Narita Professor
- 2015/09 - 2024/03 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Pharmacy
- 2007/04 - 2015/08 Kyoto University Institute for Chemical Research
- 2005/12 - 2007/03 Kyoto University Institute for Chemical Research
- 2005/04 - 2005/11 The University of Tokushima
Awards (1):
Association Membership(s) (3):
THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
, American Chemical Society
, THE PHARMACEUTICAL SOCIETY OF JAPAN
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