Matsuo Kazuya

マツオカズヤ | Matsuo Kazuya

Affiliation and department：
Job title： Assistant professor
Homepage URL (1)： http://www.cis.kit.ac.jp/~antisen/seijo.html

Research field (3)： Biochemistry , Chemical biology , Molecular biochemistry

Research keywords (5)： Photopharmacology , 光化学 , Medicinal chemistry , Bioorganic Chemistry , Chemical Biology

Research theme for competitive and other funds (9)：

2022 - 2024 Development of photocaged reagents for specific persulfidation
2022 - 2024 Chemical construction of a photoreactive protein using a photopharmacological ligand
2019 - 2024 Principle of body malfunctioning through local cell division failure
2021 - 2023 Development of smart drugs for the sensing and inhibition of target biomolecules
2020 - 2022 Molecular movies for protein-ligand association and dissociation

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Papers (27)：

Kazuya Matsuo, Honoka Ogawa, Shusuke Yamaoka, Tomonori Waku, Akio Kobori. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorganic & Medicinal Chemistry Letters. 2024. 111. 129892-129892
Kazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki. A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells. RSC Medicinal Chemistry. 2024. 15. 11. 3795-3799
Kazuya Matsuo, Machiko Kitamura, Kentaro Kobata, Daiki Unita, Tomonori Waku, Akio Kobori. Photo-cross-linking reactions in RNA-DNA heteroduplexes using photoreactive DNA incorporated with diazirine and aryl azide warheads. Chemistry Letters. 2024. 53. 8
Yu Watari, Kaito Nakatani, Kentaro Kobata, Kazuya Matsuo, Tomonori Waku, Akio Kobori. Ratiometric sandwich-type assays for RNAs with a point mutation using benzo[a]pyrene-modified probes. Chemical Communications. 2024. 60. 59. 7610-7613
Kazuya Matsuo, Ryota Uehara, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki. Spatiotemporal regulation of CENP-E-guided chromosomes using a fast-relaxing arylazopyrazole photoswitch. Chemical Communications. 2024

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Patents (2)：

Books (7)：

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Lectures and oral presentations (16)：

Photoswitchable chemical tools for the regulation and control of mitotic cell division
(2024)
Screening and analysis of chemical library for the arylazopyrazole type of photopharmacological ligands prepared by the cyclization reaction
(2024)
細胞内チオール種を超硫黄化する試薬の開発
(日本化学会第104春季年会(2024) 2024)
細胞分裂の光操作技術
(分子夾雑に挑む化学@わかやま 2023)
コバレントに機能する光制御型有糸分裂阻害剤の開発
(第13回4大学連携研究フォーラム 2023)

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Education (3)：

2010 - 2014 Kyoto university Guraduate School of Engineering Department of Synthetic Chemistry and Biological Chemistry
2008 - 2010 Nagoya City University Graduate School of Pharmaceutical Science
2004 - 2008 Nagoya City University Pharmaceutical Science

Professional career (1)：

Work history (4)：

2021/10 - 現在 Kyoto Institute of Technology
2015/06 - 2021/09 Hokkaido university Research Institute for Electronic Science Assistant professor
2014/06 - 2015/05 The Scripps research Institute Research Associate
2014/04 - 2014/05 京都大学大学院工学研究科博士研究員

Awards (5)：

Association Membership(s) (4)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE CHEMICAL SOCIETY OF JAPAN , 日本バイオイメージング学会 , 日本ケミカルバイオロジー学会

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