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J-GLOBAL ID：201501099754572428   Update date: Apr. 12, 2025

Matsuo Kazuya

マツオ カズヤ | Matsuo Kazuya
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Affiliation and department：
Kyoto Institute of Technology

About Kyoto Institute of Technology


Job title： Assistant professor
Homepage URL  (1)： http://www.cis.kit.ac.jp/~antisen/seijo.html
Research field  (3)： Biochemistry ,  Chemical biology ,  Molecular biochemistry
Research keywords  (5)： Photopharmacology ,  光化学 ,  Medicinal chemistry ,  Bioorganic Chemistry ,  Chemical Biology
Research theme for competitive and other funds  (9)：
  • 2022 - 2024 Development of photocaged reagents for specific persulfidation
  • 2022 - 2024 Chemical construction of a photoreactive protein using a photopharmacological ligand
  • 2019 - 2024 Principle of body malfunctioning through local cell division failure
  • 2021 - 2023 Development of smart drugs for the sensing and inhibition of target biomolecules
  • 2020 - 2022 Molecular movies for protein-ligand association and dissociation
Show all
Papers (29)：
  • Kentaro Kobata, Kazuki Matsubara, Risa Nishikawa, Yuki Narita, Kazuya Matsuo, Tomonori Waku, Akio Kobori. Oligonucleotide-based telomerase inhibitors with a photoresponsive α-chloroaldehyde. Bioorganic & Medicinal Chemistry Letters. 2025. 120. 130138-130138
  • Kentaro Kobata, Daiki Unita, Kazuya Matsuo, Tomonori Waku, Akio Kobori. Point Mutation Selective Photo-Cross-Linking Reactions by Diazirine-Derivatized ODNs. The Journal of Organic Chemistry. 2025
  • Kazuya Matsuo, Honoka Ogawa, Shusuke Yamaoka, Tomonori Waku, Akio Kobori. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorganic & Medicinal Chemistry Letters. 2024. 111. 129892-129892
  • Kazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki. A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells. RSC Medicinal Chemistry. 2024. 15. 11. 3795-3799
  • Kazuya Matsuo, Machiko Kitamura, Kentaro Kobata, Daiki Unita, Tomonori Waku, Akio Kobori. Photo-cross-linking reactions in RNA-DNA heteroduplexes using photoreactive DNA incorporated with diazirine and aryl azide warheads. Chemistry Letters. 2024. 53. 8
ｍore...
Patents (2)：
  • タンパク質の標識化合物
  • アシルニトロソ誘導体環化付加アントラセン誘導体および光作動型HNO供与体
Books (8)：
  • 新・講座:シスートランス異性体の化学 2シスートランス異性体による生理活性の制御
    化学と教育 2025
  • Photopharmacological ligands for the dynamic control of cell functions
    2024
  • 三者複合体を形成する分子ツールとしての農薬Mandipropamid
    ファルマシア 2022
  • 若手研究者からのメッセージ
    日本化学会バイオテクノロジー部会 NEWS LETTER 2022
  • 細胞分裂を精密に光操作する技術の確立
    新学術領域「高速分子動画」News Letter 2022
ｍore...
Lectures and oral presentations  (21)：
  • Development of chemical tools for the photocontrol of reactive sulfur species in cells
    (2025)
  • Photocontrol of mitotic cell division using chemical tools
    (JoinTECH - Collaborative Seminar with Ca’Foscari University of Venice and Kyoto Institute of Technology 2025)
  • Development of a chemical toolbox for the photoswitchable CENP-E inhibitors
    (2024)
  • 細胞内チオール環境を光制御する分子ツールの開発
    (第18回バイオ関連化学シンポジウム 2024)
  • Photoswitchable chemical tools for the regulation and control of mitotic cell division
    (2024)
ｍore...
Education (3)：
  • 2010 - 2014 Kyoto university Guraduate School of Engineering Department of Synthetic Chemistry and Biological Chemistry
  • 2008 - 2010 Nagoya City University Graduate School of Pharmaceutical Science
  • 2004 - 2008 Nagoya City University Pharmaceutical Science
Professional career (1)：
  • Ph.D. in Engineering (Kyoto university)
Work history (4)：
  • 2021/10 - 現在 Kyoto Institute of Technology
  • 2015/06 - 2021/09 Hokkaido university Research Institute for Electronic Science Assistant professor
  • 2014/06 - 2015/05 The Scripps research Institute Research Associate
  • 2014/04 - 2014/05 京都大学大学院 工学研究科 博士研究員
Awards (5)：
  • 2022/12 - 有機合成化学協会 研究企画賞
  • 2021/09 - 日本化学会生体機能関連化学部会・日本化学会バイオテクノロジー部会 第15回バイオ関連化学シンポジウム 講演賞 可視光による分裂期染色体の光操作法
  • 2019/06 - 日本ケミカルバイオロジー学会 日本ケミカルバイオロジー学会第14回年会 ポスター賞 分裂期染色体の光操作
  • 2019/02 - コニカミノルタ画像科学技術振興財団 画像科学奨励賞(優秀賞) 細胞内バイオマシンのピンポイント光操作系の構築
  • 2013/03 - 日本化学会 第93回日本化学会春季年会 学生講演賞
Association Membership(s) (4)：
THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  日本バイオイメージング学会 ,  日本ケミカルバイオロジー学会
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