Art

J-GLOBAL ID：201502260645772092   Reference number：15A0666779

The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC

AURKA/TPX2軸はMYCと協調して結腸腫瘍形成をもたらす

Author (24)： TAKAHASHI Y. (Kyushu Univ. Beppu Hospital, Beppu) ,  TAKAHASHI Y. (Osaka Univ., Suita) ,  SHERIDAN P. (Univ. Tokyo, Tokyo) ,  NIIDA A. (Univ. Tokyo, Tokyo) ,  SAWADA G. (Kyushu Univ. Beppu Hospital, Beppu) ,  SAWADA G. (Osaka Univ., Suita) ,  UCHI R. (Kyushu Univ. Beppu Hospital, Beppu) ,  MIZUNO H. (Chugai Pharmaceutical Co., Ltd, Kamakura) ,  KURASHIGE J. (Kyushu Univ. Beppu Hospital, Beppu) ,  SUGIMACHI K. (Kyushu Univ. Beppu Hospital, Beppu) ,  SASAKI S. (Omori Red Cross Hospital, Tokyo) ,  SHIMADA Y. (National Cancer Center Hospital, Tokyo) ,  HASE K. (National Defense Medical Coll., Tokorozawa) ,  KUSUNOKI M. (Mie Univ., Tsu) ,  KUDO S. (Showa Univ. Northern Yokohama Hospital, Yokohama) ,  WATANABE M. (Kitasato Univ., Sagamihara) ,  YAMADA K. (Takano Hospital, Kumamoto) ,  SUGIHARA K. (Tokyo Medical and Dental Univ., Tokyo) ,  YAMAMOTO H. (Osaka Univ., Suita) ,  SUZUKI A. (Kyushu Univ., Fukuoka, JPN) ,  DOKI Y. (Osaka Univ., Suita) ,  MIYANO S. (Univ. Tokyo, Tokyo) ,  MORI M. (Osaka Univ., Suita) ,  MIMORI K. (Kyushu Univ. Beppu Hospital, Beppu)
Material： Annals of Oncology  (Ann Oncol)
Volume： 26  Issue： 5  Page： 935-942  Publication year： May. 2015 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *colonic neoplasm ,...
Semi thesaurus term： tumorigenesis ,...

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JST classification (2)： Carcinogenic mechanisms and factors  (GE02020C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (21)：

• Kozma L, Kiss I, Szakall S, Ember I. Investigation of c-myc oncogene amplification in colorectal cancer. Cancer Lett 1994; 81: 165-169.
• Blancato J, Singh B, Liu A, Liao DJ, Dickson RB. Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses. Br J Cancer 2004; 90: 1612-1619.
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• Kessler JD, Kahle KT, Sun T et al. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science 2012; 335: 348-353.

Terms in the title (4)： TPX2 ,  Myc ,  協調 ,  結腸腫瘍