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Co-authoring Researcher

  • Shirakawa Ryutaro
    National Institute of Infectious Diseases Department of Biochemistry and Cell Biology
  • TADAOMI TAKENAWA
    Kobe University Graduate School of Medicine, Faculty of Medical Sciences, KOBE University Graduate School of Medicine
    生化学 細胞生物学 細胞内情報伝達, biochemistry cell biology signal transduction
  • FURUSE MIKIO
    National Institute for Physiological Sciences
    上皮極性, tricellular junction, tight junction, cell adhesion, epithelial cells

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J-GLOBAL ID:201601013970746240 Update date: Oct. 28, 2024

Tomohito Higashi

ヒガシ トモヒト | Tomohito Higashi
Clips

Papers (44)

  • Atsuko Y Higashi, Akira C Saito, Tomohito Higashi, Kyoko Furuse, Mikio Furuse, Hideki Chiba, Junichiro J Kazama. Bicellular Localization of Tricellular Junctional Protein Angulin-3/ILDR2 Allows Detection of Podocyte Injury. American Journal of Pathology. 2024. 194. 5. 673-683
  • Tomohito Higashi, Akira C Saito, Hideki Chiba. Damage control of epithelial barrier function in dynamic environments. European Journal of Cell Biology. 2024. 103. 2. 151410-151410
  • Tomohito Higashi, Rachel E Stephenson, Cornelia Schwayer, Karla Huljev, Atsuko Y Higashi, Carl-Philipp Heisenberg, Hideki Chiba, Ann L Miller. ZnUMBA - a live imaging method to detect local barrier breaches. Journal of Cell Science. 2023. 136. 15
  • Akira C Saito, Tomohito Higashi, Hideki Chiba. Tight-junction strand networks and tightness of the epithelial barrier. Microscopy (Oxford, England). 2023. 72. 3. 213-225
  • Tomohito Higashi, Akira C Saito, Yugo Fukazawa, Mikio Furuse, Atsuko Y Higashi, Masahiro Ono, Hideki Chiba. EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier. Journal of Cell Biology. 2023. 222. 1
  • Yuta Endo, Kotaro Sugimoto, Makoto Kobayashi, Yasuyuki Kobayashi, Manabu Kojima, Shigenori Furukawa, Shu Soeda, Takafumi Watanabe, Atsuko Y Higashi, Tomohito Higashi, et al. Claudin-9 is a novel prognostic biomarker for endometrial cancer. International Journal of Oncology. 2022. 61. 5
  • Akira C Saito, Chisato Endo, Yugo Fukazawa, Tomohito Higashi, Hideki Chiba. Effects of TAMP family on the tight junction strand network and barrier function in epithelial cells. Annals of the New York Academy of Sciences. 2022
  • Atsuko Y Higashi, Tomohito Higashi, Kyoko Furuse, Kana Ozeki, Mikio Furuse, Hideki Chiba. Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland. Scientific Reports. 2021. 11. 1. 21642-21642
  • Masayuki Watanabe, Tomohito Higashi, Kana Ozeki, Atsuko Y Higashi, Kotaro Sugimoto, Hayato Mine, Hironori Takagi, Yuki Ozaki, Satoshi Muto, Naoyuki Okabe, et al. CLDN15 is a novel diagnostic marker for malignant pleural mesothelioma. Scientific Reports. 2021. 11. 1. 12554-12554
  • Akira C Saito, Tomohito Higashi, Yugo Fukazawa, Tetsuhisa Otani, Masashi Tauchi, Atsuko Y Higashi, Mikio Furuse, Hideki Chiba. Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function. Molecular Biology of the Cell. 2021. 32. 8. mbcE20070464-738
  • Yukako Oda, Taichi Sugawara, Yuko Fukata, Yasushi Izumi, Tetsuhisa Otani, Tomohito Higashi, Masaki Fukata, Mikio Furuse. The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts. Journal of Biological Chemistry. 2020
  • Tomohito Higashi, Hideki Chiba. Molecular organization, regulation and function of tricellular junctions. Biochimica et Biophysica Acta (Biomembranes). 2020. 1862. 2. 183143-183143
  • Rachel E Stephenson, Tomohito Higashi, Ivan S Erofeev, Torey R Arnold, Marcin Leda, Andrew B Goryachev, Ann L Miller. Rho Flares Repair Local Tight Junction Leaks. Developmental Cell. 2019. 48. 4. 445-459
  • Torey R Arnold, Joseph H Shawky, Rachel E Stephenson, Kayla M Dinshaw, Tomohito Higashi, Farah Huq, Lance A Davidson, Ann L Miller. Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network. eLife. 2019. 8
  • Tomohito Higashi, Rachel E Stephenson, Ann L Miller. Comprehensive analysis of formin localization in Xenopus epithelial cells. Molecular Biology of the Cell. 2019. 30. 1. 82-95
  • Tomohito Higashi, Ann L. Miller. Tricellular junctions: how to build junctions at the TRICkiest points of epithelial cells. Molecular Biology of the Cell. 2017. 28. 15. 2023-2034
  • Tomohito Higashi, Torey R. Arnold, Rachel E. Stephenson, Kayla M. Dinshaw, Ann L. Miller. Maintenance of the Epithelial Barrier and Remodeling of Cell-Cell Junctions during Cytokinesis. Current Biology. 2016. 26. 14. 1829-1842
  • Elaina B. Breznau, Ansley C. Semack, Tomohito Higashi, Ann L. Miller. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Molecular Biology of the Cell. 2015. 26. 13. 2439-2455
  • Tomohito Higashi, Tatsuya Katsuno, Shin-ichiro Kitajiri, Mikio Furuse. Deficiency of Angulin-2/ILDR1, a Tricellular Tight Junction-Associated Membrane Protein, Causes Deafness with Cochlear Hair Cell Degeneration in Mice. PLoS One. 2015. 10. 3. e0120674
  • Nayoung K. D. Kim, Tomohito Higashi, Kyoung Yeul Lee, Ah Reum Kim, Shin-ichiro Kitajiri, Min Young Kim, Mun Young Chang, Veronica Kim, Seung-Ha Oh, Dongsup Kim, et al. Downsloping High-Frequency Hearing Loss Due to Inner Ear Tricellular Tight Junction Disruption by a Novel ILDR1 Mutation in the Ig-Like Domain. PLoS One. 2015. 10. 2. e0116931

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