Rchr
J-GLOBAL ID：201601014828632498
Update date: Nov. 10, 2025
Daisuke Komura
コウムラ ダイスケ | Daisuke Komura
Affiliation and department：
Job title：
Junior Associate Professor
Research field (4)：
Human pathology
, Biological, health, and medical informatics
, Intelligent informatics
, Systems genomics
Research keywords (4)：
Digital Pathology
, Bioinformatics
, Computer Vision
, Machine leanring
Research theme for competitive and other funds (5)：
- 2021 - 2025 深層テクスチャを用いたがん病理組織像の大規模解析基盤の構築と検証
- 2018 - 2021 胸腔系浸潤肺癌PDXのCASTIN解析によるがん幹細胞いかり分子機構の解明
- 2017 - 2020 1細胞がんー間質相互作用解析による抗癌剤耐性克服ターゲットの探索
- 2016 - 2019 The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.
- 2016 - 2018 Deep Learningを用いたデジタル病理画像からの遺伝子変異推定
Papers (88)：
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Tong Ding, Sophia J. Wagner, Andrew H. Song, Richard J. Chen, Ming Y. Lu, Andrew Zhang, Anurag J. Vaidya, Guillaume Jaume, Muhammad Shaban, Ahrong Kim, et al. A multimodal whole-slide foundation model for pathology. Nature Medicine. 2025
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Takahiro Kato, Daisuke Komura, Binay Panda, Shumpei Ishikawa. Medicine for artificial intelligence: applying a medical framework to AI anomalies. Frontiers in Artificial Intelligence. 2025. 8
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Yudai Hirano, Motoyuki Umekawa, Satoru Miyawaki, Yu Sakai, Hirotaka Hasegawa, Yu Teranishi, Shotaro Ogawa, Daisuke Komura, Hiroto Katoh, Masako Ikemura, et al. Two molecular subtypes of skull base meningiomas with extracranial extension. Acta neuropathologica communications. 2025. 13. 1. 201-201
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Yudai Hirano, Satoru Miyawaki, Yu Sakai, Yu Teranishi, Motoyuki Umekawa, Takeru Hirata, Shotaro Ogawa, Daisuke Komura, Hiroto Katoh, Masako Ikemura, et al. Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis. Acta neuropathologica communications. 2025. 13. 1. 168-168
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Maiko Tsuchiya, Yoshinao Kikuchi, Daisuke Komura, Naohiro Makise, Toru Motoi, Kimihide Kusafuka, Satoru Toyosawa, Ryosuke Hirata, Satoru Ogane, Mariko Yasui, et al. Pseudopapillary Osteoblastic Tumor With Psammomatous/Dot-Like Calcification of the Jawbone: A Report of a Hitherto Undescribed Morphologic Variant of Osteoblastoma Supported by Molecular Analysis. The American journal of surgical pathology. 2025
ｍore...
MISC (42)：
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Takuma Kobayashi, Mateusz Grynkiewicz, Hiroyuki Sano, Daisuke Komura, Mieko Ochi, Shumpei Ishikawa, Teppei Konishi. AI immuno-profiling: Predicting T and B cells directly from H&E-stained slides. Journal of Clinical Oncology. 2025. 43. e13592-e13592
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高尾 茉希, 越智 三枝子, 河村 大輔, 石川 俊平. AI を用いた病理画像解析と診断支援. 胆と膵. 2025. 46. 4. 391-398
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Kenji Harada, Yuichiro Nomura, Daisuke Komura, Shumpei Ishikawa, Shingo Sakashita. Label Noise in Pathological Segmentation is Overlooked, Leading to Potential Overestimation of Artificial Intelligence Models. 2025
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Daisuke Komura, Maki Takao, Mieko Ochi, Takumi Onoyama, Hiroto Katoh, Hiroyuki Abe, Hiroyuki Sano, Teppei Konishi, Toshio Kumasaka, Tomoyuki Yokose, et al. Comprehensive Pathological Image Segmentation via Teacher Aggregation for Tumor Microenvironment Analysis. 2025
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Tong Ding, Sophia J. Wagner, Andrew H. Song, Richard J. Chen, Ming Y. Lu, Andrew Zhang, Anurag J. Vaidya, Guillaume Jaume, Muhammad Shaban, Ahrong Kim, et al. Multimodal Whole Slide Foundation Model for Pathology. 2024
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Patents (7)：
Books (4)：
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がんゲノム病理学 第2版
文光堂 2025 ISBN:9784830604980
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医療とAI最前線 先進医療NAVIGATOR
日本医学出版 2022 ISBN:4865770496
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Molecular Pathology or Cancer Genomics
2021
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動き始めたがんゲノム医療 : 深化と普及のための基礎研究課題
羊土社 2018 ISBN:9784758103732
Lectures and oral presentations (114)：
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Single-cell profiling of tumor-infiltrating B cells reveals autoantibody repertoires and potential cross-talk with T cells
(AACR Special Conference in Cancer Research: Mechanisms of Cancer Immunity and Cancer-related Autoimmunity 2025)
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Tumor Genetics Sculpt Synergistic Innate Immunity: A Histamine Axis via Heterogeneity-Aware Models of Pleural Mesothelioma
(Dubrovnik Conference on Cancer Mechanisms and Drug Discovery 2025)
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Identification of ARID4B as a Effect Modulator of NFIB using single-cell DNA sequencing-based method for SCNA phylogeny reconstruction
(Dubrovnik Conference on Cancer Mechanisms and Drug Discovery 2025)
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AI-powered quantification of tumor-infiltrating lymphocytes from H&E stained images in ovarian cancer and its association with PARP inhibitor therapy outcomes
(2025 ASCO Annual Meeting 2025)
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Primary Pulmonary Notochord Cell Tumor: A Clinicopathological Analysis of 10 Cases and Histopathological Comparison with Conventional Chordoma and Benign Notochordal Cell Tumor
(2025 USCAP Annual Meeting 2025)
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Works (4)：
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deeptexture : Tools for deep texture representation for histology images
2023 - 現在
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Viola: flexible and powerful python package designed specifically for analysis of genomic structural variant (SV) signatures
2022 - 現在
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Luigi : Large-scale histopathological image retrieval system
2018 - 現在
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GEMCA: Genotyping Microarray based CNV Analysis
2006 -
Professional career (1)：
- PhD in Engineering (The University of Tokyo)
Work history (6)：
Committee career (4)：
- 2025/09 - 現在 日本癌学会 学術評議員
- 2024/04 - 現在 日本病理学会 学術評議員
- 2023/06 - 現在 日本病理学会 病理AIガイドライン策定ワーキンググループ 委員
- 2023/09 - 2024/10 BMC Cancer Editorial Board Member
Awards (1)：
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