Research field (4):
Human pathology
, Biological, health, and medical informatics
, Intelligent informatics
, Systems genomics
Research keywords (4):
Digital Pathology
, Bioinformatics
, Computer Vision
, Machine leanring
Research theme for competitive and other funds (5):
2021 - 2025 深層テクスチャを用いたがん病理組織像の大規模解析基盤の構築と検証
2018 - 2021 胸腔系浸潤肺癌PDXのCASTIN解析によるがん幹細胞いかり分子機構の解明
2017 - 2020 1細胞がんー間質相互作用解析による抗癌剤耐性克服ターゲットの探索
2016 - 2019 The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.
2016 - 2018 Deep Learningを用いたデジタル病理画像からの遺伝子変異推定
Papers (79):
Seiei Torazawa, Satoru Miyawaki, Hideaki Imai, Hiroki Hongo, Daiichiro Ishigami, Masahiro Shimizu, Yu Sakai, Shotaro Ogawa, Satoshi Kiyofuji, Satoshi Koizumi, et al. Association of rare variants in RNF213 with severe progression of intracranial artery stenosis in quasi-moyamoya disease. Journal of neurosurgery. 2024. 1-10
Sae Ito, Ryo Matsunaga, Makoto Nakakido, Daisuke Komura, Hiroto Katoh, Shumpei Ishikawa, Kouhei Tsumoto. High-throughput system for the thermostability analysis of proteins. Protein science : a publication of the Protein Society. 2024. 33. 6. e5029
河村 大輔, 斧山 巧, 越智 三枝子, 加藤 洋人, 牛久 哲男, 石川 俊平. 同一標本に対するH&E染色と免疫染色を利用した細胞セグメンテーションのためのがん病理組織像データセットの開発(SegPath: cancer histopathology dataset for cell segmentation using H&E staining and immunostaining on the same specimen). 日本病理学会会誌. 2022. 111. 2. 121-121
Comprehensive analysis integrating single-cell spatial transcriptomics, genomics, and histology in gastric cancer
(scverse Conference 2024 2024)
AI-based quantification of TILs using hematoxylin and eosin and immunohistochemistry-stained slides in triple-negative breast cancer
(2024 ASCO Annual Meeting 2024)
Deep learning-based quantitative assessment of tumor-infiltrating lymphocytes from hematoxylin and eosin-stained slides in triple-negative breast cancer: A prognostic study
(2024 ASCO Annual Meeting 2024)
Immunoglobulin Repertoire Sequencing of Tumor-Infiltrating B cells Identifies Therapeutically Applicable Anti-Tumor Human Antibodies
(Keystone Symposia "Antibodies as Drugs: The Art in Antibody Engineering" 2024)
Translational Research of CDK12/13 Inhibitor, CTX-439, Informing Clinical Trial Strategy
(American Association for Cancer Research 2024)