Daisuke Komura

コウムラダイスケ | Daisuke Komura

Affiliation and department：
Job title： Assistant Professor

Research field (4)： Human pathology , Biological, health, and medical informatics , Intelligent informatics , Systems genomics

Research keywords (4)： Digital Pathology , Bioinformatics , Computer Vision , Machine leanring

Research theme for competitive and other funds (5)：

2021 - 2025 深層テクスチャを用いたがん病理組織像の大規模解析基盤の構築と検証
2018 - 2021 胸腔系浸潤肺癌PDXのCASTIN解析によるがん幹細胞いかり分子機構の解明
2017 - 2020 1細胞がんー間質相互作用解析による抗癌剤耐性克服ターゲットの探索
2016 - 2019 The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.
2016 - 2018 Deep Learningを用いたデジタル病理画像からの遺伝子変異推定

Papers (79)：

Seiei Torazawa, Satoru Miyawaki, Hideaki Imai, Hiroki Hongo, Daiichiro Ishigami, Masahiro Shimizu, Yu Sakai, Shotaro Ogawa, Satoshi Kiyofuji, Satoshi Koizumi, et al. Association of rare variants in RNF213 with severe progression of intracranial artery stenosis in quasi-moyamoya disease. Journal of neurosurgery. 2024. 1-10
Yudai Hirano, Satoru Miyawaki, Yu Sakai, Yu Teranishi, Atsushi Okano, Motoyuki Umekawa, Hiroki Hongo, Seiei Torazawa, Shotaro Ogawa, Daisuke Komura, et al. Genetic analysis of foramen magnum meningiomas reveals AKT1 mutations uncomplicated by TRAF7 mutations. Acta neuropathologica communications. 2024. 12. 1. 123-123
Mieko Ochi, Daisuke Komura, Shumpei Ishikawa. Pathology Foundation Models. 2024
Ranny R Herdiantoputri, Daisuke Komura, Mieko Ochi, Yuki Fukawa, Kou Kayamori, Maiko Tsuchiya, Yoshinao Kikuchi, Tetsuo Ushiku, Tohru Ikeda, Shumpei Ishikawa. Benchmarking Deep Learning-Based Image Retrieval of Oral Tumor Histology. Cureus. 2024. 16. 6. e62264
Sae Ito, Ryo Matsunaga, Makoto Nakakido, Daisuke Komura, Hiroto Katoh, Shumpei Ishikawa, Kouhei Tsumoto. High-throughput system for the thermostability analysis of proteins. Protein science : a publication of the Protein Society. 2024. 33. 6. e5029

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MISC (34)：

Daisuke Komura, Shumpei Ishikawa. Meet the authors: Daisuke Komura and Shumpei Ishikawa. Patterns (New York, N.Y.). 2023. 4. 7. 100794-100794
河村大輔, 石川俊平. 腫瘍微小環境の空間トランスクリプトーム解析. 遺伝子医学. 2023. 13. 3. 78-83
渡部朱織, 菊地良直, 河村大輔, 宇於崎宏. 大腸癌と胃癌の播種巣における中皮間葉転換の誘導と免疫抑制微小環境の形成. 日本病理学会会誌. 2023. 112. 1. 278-278
越智三枝子, 河村大輔, 斧山巧, 新保幸輝, 遠藤春哉, 牛久哲男, 石川俊平. 多種撮像媒体および染色条件による多様なH&E染色病理画像データセットの構築とその活用. 日本病理学会会誌. 2023. 112. 1. 339-339
河村大輔, 斧山巧, 越智三枝子, 加藤洋人, 牛久哲男, 石川俊平. 同一標本に対するH&E染色と免疫染色を利用した細胞セグメンテーションのためのがん病理組織像データセットの開発(SegPath: cancer histopathology dataset for cell segmentation using H&E staining and immunostaining on the same specimen). 日本病理学会会誌. 2022. 111. 2. 121-121

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Patents (7)：

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Books (3)：

Lectures and oral presentations (103)：

Comprehensive analysis integrating single-cell spatial transcriptomics, genomics, and histology in gastric cancer
(scverse Conference 2024 2024)
AI-based quantification of TILs using hematoxylin and eosin and immunohistochemistry-stained slides in triple-negative breast cancer
(2024 ASCO Annual Meeting 2024)
Deep learning-based quantitative assessment of tumor-infiltrating lymphocytes from hematoxylin and eosin-stained slides in triple-negative breast cancer: A prognostic study
(2024 ASCO Annual Meeting 2024)
Immunoglobulin Repertoire Sequencing of Tumor-Infiltrating B cells Identifies Therapeutically Applicable Anti-Tumor Human Antibodies
(Keystone Symposia "Antibodies as Drugs: The Art in Antibody Engineering" 2024)
Translational Research of CDK12/13 Inhibitor, CTX-439, Informing Clinical Trial Strategy
(American Association for Cancer Research 2024)

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Works (4)：

deeptexture : Tools for deep texture representation for histology images
2023 - 現在
Viola: flexible and powerful python package designed specifically for analysis of genomic structural variant (SV) signatures
2022 - 現在
Luigi : Large-scale histopathological image retrieval system
2018 - 現在
GEMCA: Genotyping Microarray based CNV Analysis
2006 -

Professional career (1)：

Committee career (3)：

Awards (1)：

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