Art

J-GLOBAL ID：201602228447293688   Reference number：16A0948415

Activation of human bitter taste receptors by polymethoxylated flavonoids

ポリメトキシフラボノイドによるヒト苦味受容体の活性化

Author (7)： KURODA Yuki (Univ. Shizuoka, Shizuoka, JPN) ,  IKEDA Riko (Univ. Shizuoka, Shizuoka, JPN) ,  YAMAZAKI Toyomi (Univ. Shizuoka, Shizuoka, JPN) ,  ITO Keisuke (Univ. Shizuoka, Shizuoka, JPN) ,  UDA Kazunari (Univ. Shizuoka, Shizuoka, JPN) ,  WAKABAYASHI Keiji (Univ. Shizuoka, Shizuoka, JPN) ,  WATANABE Tatsuo (Univ. Shizuoka, Shizuoka, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 80  Issue： 10  Page： 2014-2017  Publication year： Oct. 2016 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *flavonoid ,...
Semi thesaurus term： citrus

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JST classification (4)： Food quality  (FJ01040F) ,  Fruit trees  (FC03042G) ,  Aromatic monocyclic phenols and polyphenols  (CF05090V) ,  Other senses  (EJ13040X)

Substance index (2)： Tangeretin ,  Nobiletin

Reference (24)：

• Wang Z, Li S, Ferguson S, et al. Validated reversed phase LC method for quantitative analysis of polymethoxyflavones in citrus peel extracts. J. Sep. Sci. 2008;31:30-37.
• Saito T, Abe D, Nogata Y. Polymethoxylated flavones potentiate the cytolytic activity of NK leukemia cell line KHYG-1 via enhanced expression of granzyme B. Biochem. Biophys. Res. Commun. 2015;456:799-803.
• Yuen H-Q, Hwang Q-H, Zhang X-Y, et al. Cellular antioxidant activity and pharmacokinetic study of polymethoxylated flavonoids in extract of citrus reticulata ‘Chachi' peel. Food Sci. Technol. Res. 2014;20:629-637.
• Kurowska EM, Manthey JA. Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia. J. Agric. Food Chem. 2004;52:2879-2886.
• Nakajima A, Yamakuni T, Haraguchi M, et al. Nobiletin, a citrus flavored that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice. J. Pharmacol. Sci. 2007;105:122-126.

Terms in the title (4)： ポリメトキシフラボノイド ,  ヒト ,  苦味受容体 ,  活性化