Art

J-GLOBAL ID：201702210484665795   Reference number：17A1153766

Investigations of invasive streptococcal infection based on next generation sequencing

次世代シーケンス(NGS)による劇症型レンサ球菌の病原性解析

Author (4)： TAKEMOTO NORIHIKO (国立国際医療研究セ 研) ,  OGURA KOHEI (国立国際医療研究セ 研) ,  WATANABE SHIN'YA (自治医大 感染・免疫学 細菌学部門) ,  AKIYAMA TOORU (国立国際医療研究セ 研)
Material： 日本化学療法学会雑誌  (Japanese Journal of Chemotherapy)
Volume： 65  Issue： 5  Page： 745-750  Publication year： Sep. 10, 2017 
JST Material Number： F0608A  ISSN： 1340-7007  CODEN： NKRZE5  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *Streptococcus ,...
Semi thesaurus term： genetic variation ,...

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JST classification (3)： Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Physiology and pathogenicity of microbial infection  (EG03053T) ,  Research methods in genetics  (EC01020N)

Reference (9)：

• Carapetis J R, Steer A C, Mulholland E K, Weber M: The global burden of group A streptococcal diseases. Lancet Infect Dis 2005; 5: 685-94
• Miyoshi-Akiyama T, Zhao J, Kikuchi K, Kato H, Suzuki R, Endoh M, et al: Quantitative and qualitative comparison of virulence traits, including murine lethality, among different M types of group A streptococci. J Infect Dis 2003; 187: 1876-87
• Graham M R, Smoot L M, Migliaccio C A, Virtaneva K, Sturdevant D E, Porcella S F, et al: Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci U S A 2002; 99: 13855-60
• Miyoshi-Akiyama T, Ikebe T, Watanabe H, Uchiyama T, Kirikae T, Kawamura Y: Use of DNA arrays to identify a mutation in the negative regulator, csrR, responsible for the high virulence of a naturally occurring type M3 group A streptococcus clinical isolate. J Infect Dis 2006; 193: 1677-84
• Walker M J, Hollands A, Sanderson-Smith M L, Cole J N, Kirk J K, Henningham A, et al: DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat Med 2007; 13: 981-5

Terms in the title (6)： 次世代 ,  シーケンス ,  劇 ,  レンサ球菌 ,  病原性 ,  解析