Hayashi Takeharu

ハヤシタケハル | Hayashi Takeharu

Affiliation and department：
Job title： Professor

Research field (7)： Cardiology , Internal medicine - General , Medical biochemistry , Pharmacology , Clinical pharmacy , Physiology , Anatomy

Research keywords (3)： Genome-based drug discovery , disease-causing gene , Cardiomyopathy

Research theme for competitive and other funds (9)：

2025 - 2028 Toward Delivering a Novel Therapy for Cardiomyopathy, a Designated Intractable Disease
2021 - 2026 Elucidation of pathogenesis in high-risk group hypertrophy cardiomyopathy
2024 - 2025 Towards the provision of novel therapies for cardiomyopathy
2023 - 2024 肥大型心筋症の新規治療法の開発
2017 - 2019 心筋症の遺伝的病因に基づく新規予防、治療法の開発

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Papers (51)：

Natsuko Inagaki, Yasuyoshi Takei, Tsuguhisa Hatano, Yasuyuki Takada, Yoshinao Yazaki, Hisanori Kosuge, Masatake Kobayashi, Shinji Suzuki, Tomohiro Umezu, Masahiko Kuroda, et al. Clinical characteristics of female Fabry disease patients with hypertrophic cardiomyopathy with mid-ventricular obstruction. Molecular genetics and metabolism reports. 2025. 42. 101196-101196
Natsuko Inagaki, Tomoya Okano, Masatake Kobayashi, Masatsune Fujii, Yoshinao Yazaki, Yasuyoshi Takei, Hisanori Kosuge, Shinji Suzuki, Takeharu Hayashi, Masahiko Kuroda, et al. Pediatric hypertrophic cardiomyopathy caused by a novel TNNI3 variant. Human Genome Variation. 2024
Natsuko Inagaki, Takeharu Hayashi, Yasuyoshi Takei, Hisanori Kosuge, Shinji Suzuki, Kousuke Tanimoto, Taishiro Chikamori, Akinori Kimura. Pathogenic variant of RBM20 in a multiplex family with hypertrophic cardiomyopathy. Human Genome Variation. 2022. 9. 1. 6-6
Kayoko Hirayama-Yamada, Natsuko Inagaki, Takeharu Hayashi, Akinori Kimura. A Novel Titin Truncation Variant Linked to Familial Dilated Cardiomyopathy Found in a Japanese Family and Its Functional Analysis in Genome-Edited Model Cells. International Heart Journal. 2021. 62. 2. 359-366
Takeharu Hayashi. Hypertrophic Cardiomyopathy: Diverse Pathophysiology Revealed by Genetic Research, Toward Future Therapy. The Keio journal of medicine. 2020

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MISC (19)：

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Education (2)：

- 2004 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
- 1994 Hiroshima University Faculty of Medicine

Professional career (1)：

Work history (10)：

2023/04 - 現在 Tokai University School of Medicine Faculty of Medicine Professore
2020/04 - 現在 Tokyo Dental College Visiting Professor
2019/04 - 2022/03 Tokai University School of Medicine, Faculty of Medicine Professor
2018/06 - 2019/03 Keio University School of Medicine School of Medicine Adjunct Associated Professor
2013/05 - 2018/04 Tokyo Medical and Dental University Medical Research Institute Associated Professor

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