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J-GLOBAL ID：201801019682939606   Update date: Jan. 31, 2024

Takami Masamichi

タカミ マサミチ | Takami Masamichi
Affiliation and department：
Showa University School of Dentistry

About Showa University School of Dentistry


Other affiliations (2)：
  • Kyoto University
  • Showa Pharamaceutical University
Research field  (4)： Pharmacology ,  Regenerative dentistry and dental engineering ,  Conservative dentistry and endodontics ,  Oral medicine
Research keywords  (9)： Bisphosphonate ,  Denosumab ,  Neural Crest ,  Regeneration ,  Gene ,  Pharmacology ,  Tooth ,  Bone ,  Osteoclast
Research theme for competitive and other funds  (30)：
  • 2021 - 2024 Elucidating the mechanisms of anti-bone resorptive drugs on tooth root development
  • 2021 - 2024 鰭(ひれ)の骨周囲スペースを制御する未知細胞の同定と機能解明
  • 2020 - 2024 歯と骨の恒常性維持における脂質代謝関連分子の機能解明
  • 2018 - 2021 Effects of anti-bone resorptive drugs on growth and tooth development in young mice.
  • 2017 - 2020 Development of a method for suppressing bone destruction targeting cholesterol acyltransferase.
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Papers (193)：
  • 細沼 雅弘, 坂井 信裕, 松島 英輝, 菊田 順一, 高木 孝士, 武部 明, 石井 優, 高見 正道. 光-電子相関顕微鏡法とFocused Ion Beam Scanning Electron Microscopeを用いた破骨細胞の三次元構造解析. 日本骨形態計測学会雑誌. 2023. 33. 1. 198-198
  • Yue Zhou, Aki Nishiura, Hidetoshi Morikuni, Wenqi Deng, Toru Tsujibayashi, Yoshihiro Momota, Yuki Azetsu, Masamichi Takami, Yoshitomo Honda, Naoyuki Matsumoto. RANKL+ senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics. International journal of oral science. 2023. 15. 20
  • Maho Yamaguchi, Masamichi Takami, Yuki Azetsu, Akiko Karakawa, Masahiro Chatani, Takahiro Funatsu, Nobuhiro Sakai. Effects of anti-RANKL antibodies administered to pregnant mice on bone and tooth development in neonates. Journal of oral biosciences. 2023
  • Francine Lianne Emralino, Saya Satoh, Nobuhiro Sakai, Masamichi Takami, Fumihiko Takeuchi, Nan Yan, Frank Rutsch, Takashi Fujita, Hiroki Kato. Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model. Journal of immunology (Baltimore, Md. : 1950). 2022. 209. 11. 2093-2103
  • Yurie Sato, Masahiro Hosonuma, Daiki Sugawara, Yuki Azetsu, Akiko Karakawa, Masahiro Chatani, Takahiro Funatsu, Masamichi Takami, Nobuhiro Sakai. Cholesterol and fat in diet disrupt bone and tooth homeostasis in mice. Biomedicine & Pharmacotherapy. 2022. 156. 113940-113940
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MISC (145)：
  • 山口真帆, 山口真帆, 山口真帆, 坂井信裕, 唐川亜希子, 唐川亜希子, 茶谷昌宏, 茶谷昌宏, 畔津佑季, 畔津佑季, et al. Bone resorption inhibitor administration to pregnant mice results in tooth disorder development in neonates. Journal of Oral Biosciences Supplement (Web). 2022. 2022
  • 佐藤ゆり絵, 佐藤ゆり絵, 佐藤ゆり絵, 坂井信裕, 坂井信裕, 唐川亜希子, 唐川亜希子, 畔津佑季, 畔津佑季, 茶谷昌宏, et al. Effects of fat and cholesterol intake on tooth and bone homeostasis in mice. Journal of Oral Biosciences Supplement (Web). 2021. 2021
  • 山口真帆, 山口真帆, 山口真帆, 坂井信裕, 坂井信裕, 佐藤ゆり絵, 佐藤ゆり絵, 佐藤ゆり絵, 栗谷未来, 栗谷未来, et al. 妊娠マウスへの抗RANKL抗体及びゾレドロネート投与は新生仔における歯の発生障害をもたらす. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2021. 39th
  • 瀧澤秀臣, 瀧澤秀臣, 瀧澤秀臣, 唐川亜希子, 唐川亜希子, 茶谷昌宏, 茶谷昌宏, 須澤徹夫, 坂井信裕, 坂井信裕, et al. Role of neural crest-derived cells in palate-wound healing process. Journal of Oral Biosciences Supplement (Web). 2021. 2021
  • 唐川亜希子, 唐川亜希子, 坂井信裕, 坂井信裕, 茶谷昌宏, 茶谷昌宏, 高見正道, 高見正道. 抗RANKL抗体とゾレドロネートがマウスの成長と歯の恒常性に及ぼす薬理作用の比較. 日本薬理学雑誌. 2020. 155. Supplement
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Patents (9)：
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Books (1)：
  • 解る!歯科薬理学
    学建書院 2019 ISBN:9784762426643
Lectures and oral presentations  (18)：
  • Molecular regulatory;system of osteoclasts
    (The Japanese Society for Bone and Mineral Research 2021)
  • 口蓋創傷治癒過程における神経堤由来細胞の役割(Role of neural crest-derived cells in palate-wound healing process)
    (Journal of Oral Biosciences Supplement 2021)
  • 口蓋創傷治癒過程における神経堤由来細胞の役割(Role of neural crest-derived cells in palate-wound healing process)
    (Journal of Oral Biosciences Supplement 2021)
  • 骨吸収抑制薬が実験的根尖性歯周炎の成立に及ぼす影響の解析
    (日本骨代謝学会学術集会プログラム抄録集 2021)
  • 抗RANKLモノクローナル抗体がマウス脊椎固定術モデルの骨癒合に及ぼす影響
    (日本骨形態計測学会雑誌 2021)
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Education (3)：
  • 1995 - 1998 Graduate School of Tokyo Institute of Technology
  • 1989 - 1991 Kyushu University Faculty of Agriculture
  • 1985 - 1989 Kyushu University School of Agriculture
Professional career (1)：
  • PhD (Tokyo Institute of Technology)
Work history (6)：
  • 2018/04 - 現在 Showa University Graduate School of Dentistry
  • 2013/11 - 現在 Showa University School of Dentistry
  • 2003/04 - 2013/10 Showa University School of Dentistry
  • 1998/04 - 2003/03 Showa University School of Dentistry
  • 1991/04 - 1998/03 Nippon Steel Corporation
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Awards (4)：
  • 2021/10 - Japanese Society of Bone and Mineral Research Academic Award Molecular Regulatory System of Osteoclast Differentiation
  • 2021/08 - The Society for Hard Tissue Regenerative Biology Hard Tissue Regenerative Biology Award Immunohistochemical nd the Expression of Osteoclast-Related Markers in Giant Cell Tumor of BoneAnalysis of the Distribution of RANKL-Expressing Cells a
  • 2004/11 - Kamijo Award
  • 1998/03 - Izumi Kamata Award
Association Membership(s) (7)：
The Japanese Pharmacological Society ,  Japanese Society of Osteoimmunology ,  Japanese Society of Oral Therapeutics and Pharmacology ,  Japanese Association for Oral Biology ,  The Molecular Biology Society of Japan ,  The Japanese Society for Bone and Mineral Research ,  JAPANESE ASSOCIATION FOR ANIMAL CELL TECHNOLOGY
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