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J-GLOBAL ID：201802242335714549   Reference number：18A1884968

Defects in centromeric/pericentromeric histone H2A T120 phosphorylation by hBUB1 cause chromosome missegregation producing multinucleated cells

hBUB1による動原体/動原体周囲ヒストンH2A T120のリン酸化欠損は多核細胞を産生する染色体誤分離を引き起こす

Author (15)： Maeda Katsutoshi (Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan) ,  Maeda Katsutoshi (Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Maeda Katsutoshi (Oda Clinic, Hiroshima, Japan) ,  Yoneda Mitsuhiro (Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan) ,  Nakagawa Takeya (Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan) ,  Ikeda Kazuhiro (Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan) ,  Higashi Miki (Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan) ,  Nakagawa Kaori (Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan) ,  Miyakoda Mana (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Yui Katsuyuki (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Oda Hiroaki (Oda Clinic, Hiroshima, Japan) ,  Inoue Satoshi (Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan) ,  Inoue Satoshi (Department of Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan) ,  Ito Takashi (Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki, Japan) ,  Ito Takashi (Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan)
Material： Genes to Cells  (Genes Cells)
Volume： 23  Issue： 10  Page： 828-838  Publication year： Oct. 2018 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *histone ,...
Semi thesaurus term： *histone H2A ,...

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Author keywords (4)： BUB1 ,  H2A ,  histone modification ,  phosphorylation

JST classification (3)： Cell division and proliferation  (EF02020D) ,  Enzyme in general  (EB09010D) ,  Basic oncology in general  (GE02010R)

Terms in the title (6)： 動原体 ,  ヒストンH2A ,  リン酸化 ,  欠損 ,  多核細胞 ,  染色体