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J-GLOBAL ID：201802274503463217   Reference number：18A1867082

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair

ヒトRAD52は転写関連相同組換え修復を開始するためにXPG仲介Rループプロセシングを促進する【JST・京大機械翻訳】

Author (9)： Yasuhara Takaaki (Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Kato Reona (Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Hagiwara Yoshihiko (Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan) ,  Shiotani Bunsyo (Division of Cellular Signaling, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan) ,  Yamauchi Motohiro (Division of Radiation Biology and Protection, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan) ,  Nakada Shinichiro (Department of Bioregulation and Cellular Response, Graduate School of Medicine, Osaka University, Osaka, Japan) ,  Nakada Shinichiro (Institute for Advanced Co-Creation Studies, Osaka University, Osaka, Japan) ,  Shibata Atsushi (Education and Research Support Center, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan) ,  Miyagawa Kiyoshi (Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 175  Issue： 2  Page： 558-570.e11  Publication year： 2018 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Given that genomic DNA exerts ...

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Thesaurus term： RNA ,  DNA double strand break ,  *homologous recombination ,  gene ,  DNA ,  homeostasis ,  dysfunction ,  *human ,  genome information ,  genome abnormality ,  DNA double-strand break repair ,  non-homologous end joining ,  transcriptional activity ,  genomic DNA ,  *molecular genetic phenomenon

Author keywords (8)： transcription-associated homologous recombination repair ,  DNA double-strand break ,  DNA-RNA hybrid ,  R-loop ,  Rad52 ,  XPG ,  non-homologous end-joining ,  genomic instability

JST classification (2)： Gene expression  (EC02040Q) ,  Molecular genetics in general  (EC02010J)

Terms in the title (7)： ヒト ,  Rad52 ,  転写 ,  相同組換え修復 ,  仲介 ,  プロセシング ,  促進