Art

J-GLOBAL ID：201802279759356551   Reference number：18A0574395

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors

ヒトAK2は造血前駆細胞の運命への細胞内生体エネルギー再分布に関連する【Powered by NICT】

Author (27)： Oshima Koichi (Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Saiki Norikazu (Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Tanaka Michihiro (Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Imamura Hiromi (The Hakubi Center for Advanced Research, Kyoto University, Kyoto, Kyoto, 6068501, Japan) ,  Niwa Akira (Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Tanimura Ayako (Department of Molecular Biology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Tokushima, 7708505, Japan) ,  Nagahashi Ayako (Department of Fundamental Cell Technology, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Hirayama Akiyoshi (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, 9970052, Japan) ,  Okita Keisuke (Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Hotta Akitsu (Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Kitayama Shuichi (Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Osawa Mitsujiro (Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Kaneko Shin (Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Watanabe Akira (Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Asaka Isao (Department of Fundamental Cell Technology, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Fujibuchi Wataru (Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Imai Kohsuke (Department of Community Pediatrics, Perinatal and Maternal Medicine, Tokyo Medical and Dental University, Tokyo, Tokyo, 1130034, Japan) ,  Yabe Hiromasa (Specialized Clinical Science, Pediatrics, Tokai University School of Medicine, Isehara, Kanagawa, 2591193, Japan) ,  Kamachi Yoshiro (Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Nagoya, 4668550, Japan) ,  Hara Junichi (Department of Pediatric Hematology/Oncology, Children’s Medical Center, Osaka City General Hospital, Osaka, Osaka, 5340021, Japan) ,  Kojima Seiji (Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Nagoya, 4668550, Japan) ,  Tomita Masaru (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, 9970052, Japan) ,  Soga Tomoyoshi (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, 9970052, Japan) ,  Noma Takafumi (Department of Molecular Biology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Tokushima, 7708505, Japan) ,  Nonoyama Shigeaki (Department of Pediatrics, National Defense Medical College, Tokorozawa, Saitama, 3590042, Japan) ,  Nakahata Tatsutoshi (Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan) ,  Saito Megumu K. (Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Kyoto, 6068507, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 497  Issue： 2  Page： 719-725  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： AK2 is an adenylate phosphotra...

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Thesaurus term： dysfunction ,  hematopoietic stem cell ,  *redistribution ,  induced pluripotent stem cell ,  versatility ,  Neutrophils ,  *hemopoiesis ,  patient ,  *human ,  differentiation (biology) ,  Mitochondria ,  Transcription profiling ,  *committed stem cell ,  *Hematopoietic progenitor cell
Semi thesaurus term： 重症複合型免疫不全症 , 【Automatic Indexing@JST】

Author keywords (4)： Induced pluripotent stem cells ,  Adenylate kinase 2 ,  Hemoangiogenic progenitor cells ,  Phosphotransfer

JST classification (4)： Development(=generation)and differentiation  (EJ16020W) ,  Function of cell components  (EF03060C) ,  Cell physiology in general  (EF02010S) ,  Blood in general  (EJ03010L)

Terms in the title (5)： ヒト ,  造血前駆細胞 ,  生体 ,  エネルギー ,  再分布