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J-GLOBAL ID：201802290253843307   Reference number：18A1465228

In vivo tissue distribution and safety of polyacrylic acid-modified titanium peroxide nanoparticles as novel radiosensitizers

新規放射線増感剤としてのポリアクリル酸修飾過酸化チタンナノ粒子のin vivo組織分布と安全性

Author (12)： Morita Kenta (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan) ,  Morita Kenta (Research Facility Center for Science and Technology, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan) ,  Suzuki Takahiro (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan) ,  Nishimura Yuya (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan) ,  Matsumoto Kazuhisa (Graduate School of Science, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan) ,  Numako Chiya (Graduate School of Science, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan) ,  Sato Kazuyoshi (Division of Environmental Engineering Science, Graduate School of Science and Technology, Gunma University, 1-5-1 Tenjincho, Kiryu, Gunma 376-8515, Japan) ,  Nakayama Masao (Division of Radiation Oncology, Kobe University Graduate School of Medicine, 7-5-2 Kusunokicho, Chuou-ku, Kobe 650-0017, Japan) ,  Sasaki Ryohei (Division of Radiation Oncology, Kobe University Graduate School of Medicine, 7-5-2 Kusunokicho, Chuou-ku, Kobe 650-0017, Japan) ,  Ogino Chiaki (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan) ,  Kondo Akihiko (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan) ,  Kondo Akihiko (Organization of Advanced Science and Technology, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 126  Issue： 1  Page： 119-125  Publication year： Jul. 2018 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *radiosensitizer ,...
Semi thesaurus term： BALB/c mice

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Author keywords (8)： Titanium peroxide ,  Titanium dioxide ,  Nanoparticle ,  Radiosensitizer ,  Tissue distribution ,  Acute toxicity ,  Enhanced permeability and retention effect ,  Cancer

JST classification (2)： Radiotherapy  (GC04030V) ,  Toxicity of metals and metal compounds  (GZ02022V)

Reference (32)：

• Baskar, R., Lee, K. A., Yeo, R., and Yeoh, K.-W.: Cancer and radiation therapy: current advances and future directions, Int. J. Med. Sci., 9, 193-199 (2012).
• Rockwell, S., Dobrucki, I. T., Kim, E. Y., Marrison, S. T., and Vu, V. T.: Hypoxia and radiation therapy: past history, ongoing research, and future promise, Curr. Mol. Med., 9, 442-458 (2009).
• Coulter, J. A., Hyland, W. B., Nicol, J., and Curren, F. J.: Radiosensitising nanoparticles as novel cancer therapeutics - pipe dream or realistic prospect? Clin. Oncol., 25, 593-603 (2013).
• Kwatra, D., Venugopal, A., and Anant, S.: Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer, Transl. Cancer Res., 2, 330-342 (2013).
• Su, X.-Y., Liu, P.-D., Wu, H., and Gu, N.: Enhancement of radiosensitization by metal-based nanoparticles in cancer radiation therapy, Cancer Biol. Med., 11, 86-91 (2014).

Terms in the title (6)： 放射線増感剤 ,  ポリアクリル酸 ,  修飾 ,  酸化チタンナノ粒子 ,  組織分布 ,  安全性