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Syntheses of prodrug-type phosphotriester oligonucleotides responsive to intracellular reducing environment for improvement of cell membrane permeability and nuclease resistance
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About Hayashi Junsuke
About Laboratory of Bioorganic Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan
About Samezawa Yusuke
About Laboratory of Bioorganic Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan
About Ochi Yosuke
About Laboratory of Bioorganic Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan
About Wada Shun-ichi
About Laboratory of Bioorganic Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan
About Urata Hidehito
About Laboratory of Bioorganic Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan
Material：
About Bioorganic & Medicinal Chemistry Letters
Volume： 27 Issue： 14 Page： 3135-3138 Publication year： 2017
JST Material Number： W0248A ISSN： 0960-894X Document type： Article
Article type： 原著論文 Country of issue： Netherlands (NLD) Language： ENGLISH (EN)
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About Cytosol
About robustness
About nuclease
About phosphonate
About reduction environment
About prodrug
About oligonucleotide
About phosphoric acid
About Cell Membrane Permeability
About Prodrug oligonucleotide
About Phosphotriester
About Disulfide
Category name(code) classified by JST.
About Enzyme in general
About Peptides
Keywords automatically extracted from the title.
About 細胞膜透過性
About ヌクレアーゼ
About 抵抗性
About 還元環境
About 応答
About プロドラッグ
About りん酸
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