Art

J-GLOBAL ID：201902231780904903   Reference number：19A2870849

Crim1 ^C140S mutant mice reveal the importance of cysteine 140 in the internal region 1 of CRIM1 for its physiological functions

CRI1 C14S変異マウスはその生理機能のためのCRI1の内部領域1におけるシステイン140の重要性を明らかにする【JST・京大機械翻訳】

Author (16)： Furuichi Tatsuya (Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan) ,  Furuichi Tatsuya (Department of Basic Veterinary Science, United Graduate School of Veterinary Science, Gifu University, Gifu, Japan) ,  Tsukamoto Manami (Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan) ,  Saito Masaki (Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan) ,  Sato Yuriko (Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan) ,  Oiji Nobuyasu (Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan) ,  Yagami Kazuhiro (Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan) ,  Fukumura Ryutaro (Mutagenesis and Genomics Team, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan) ,  Fukumura Ryutaro (SRL&Shizuoka Cancer Center Collaborative Laboratories, Inc., Sunto-gun, Shizuoka, Japan) ,  Gondo Yoichi (Mutagenesis and Genomics Team, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan) ,  Gondo Yoichi (Department of Molecular Life Sciences, Tokai University School of Medicine, Isehara, Kanagawa, Japan) ,  Guo Long (Laboratory for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan) ,  Ikegawa Shiro (Laboratory for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan) ,  Yamamori Yu (Artificial Intelligence Research Center (AIRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan) ,  Tomii Kentaro (Artificial Intelligence Research Center (AIRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan) ,  Tomii Kentaro (Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan)
Material： Mammalian Genome
Volume： 30  Issue： 11-12  Page： 329-338  Publication year： 2019 
JST Material Number： W0446A  ISSN： 0938-8990  CODEN： MAMGEC  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Cysteine-rich transmembrane bo...

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Thesaurus term： missense mutation ,  transmembrane protein ,  growth factor ,  Proteins ,  Phenotype ,  mutagenesis ,  osteogenic factor ,  disulfide bond ,  in vitro experiment ,  interaction ,  dwarfism (depauperation) ,  *allele ,  complex (substance) ,  seminal vesicle
Semi thesaurus term： VEGF , 【Automatic Indexing@JST】

Author keywords (5)： CRIM1 ,  ENU mouse mutagenesis ,  Whole-exome sequencing ,  Protein instability ,  BMP

JST classification (5)： Carcinogenic mechanisms and factors  (GE02020C) ,  Population genetics  (EC01040J) ,  Heart  (EJ04020D) ,  Immunotherapy for tumors  (GE03035B) ,  Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (4)： 変異マウス ,  生理機能 ,  システイン ,  重要性