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J-GLOBAL ID：201902241377788042   Reference number：19A0982431

Identification of Alprenolol Hydrochloride as an Anti-prion Compound Using Surface Plasmon Resonance Imaging

表面プラズモン共鳴イメージングを用いた抗プリオン化合物としての塩酸アルプレノロールの同定【JST・京大機械翻訳】

Author (11)： Miyazaki Yukiko (Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Miyazaki Yukiko (Program for Nurturing Global Leaders in Tropical and Emerging Infectious Diseases, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Ishikawa Takeshi (Program for Nurturing Global Leaders in Tropical and Emerging Infectious Diseases, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Ishikawa Takeshi (Molecular Epidemiology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Kamatari Yuji O. (Life Science Research Center, Gifu University, Gifu, Japan) ,  Nakagaki Takehiro (Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Takatsuki Hanae (Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan) ,  Ishibashi Daisuke (Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Kuwata Kazuo (United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan) ,  Nishida Noriyuki (Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Atarashi Ryuichiro (Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan)
Material： Molecular Neurobiology
Volume： 56  Issue： 1  Page： 367-377  Publication year： 2019 
JST Material Number： W0110A  ISSN： 0893-7648  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Prion diseases are transmissib...

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Thesaurus term： prion disease ,  human ,  *image processing ,  Mus musculus ,  *Prions ,  Food and Drug Administration ,  hot spot ,  effect ,  oral administration ,  therapy ,  protein aggregation ,  Neurodegenerative Diseases ,  *Surface Plasmon Resonance ,  Antiprion Action ,  Myomorpha ,  *Proteins ,  *glycoprotein ,  *prion protein
Semi thesaurus term： 脆弱性 ,  抗プリオン活性 , 【Automatic Indexing@JST】

Author keywords (4)： Prion diseases ,  Surface plasmon resonance imaging ,  Alprenolol hydrochloride ,  Docking simulation

JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (5)： 表面プラズモン共鳴 ,  イメージング ,  プリオン ,  塩酸アルプレノロール ,  同定