Art

J-GLOBAL ID：201902262813506149   Reference number：19A0217176

Fucoxanthin administration delays occurrence of tumors in xenograft mice by colonospheres, with an anti-tumor predictor of glycine

フコキサンチン投与はグリシンの抗腫瘍予測因子とともにcolonosphereによる異種移植マウスでの腫瘍の発生を遅延させる

Author (11)： Terasaki Masaru (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido) ,  Terasaki Masaru (Cancer Prevention Laboratories, Health Sciences University of Hokkaido) ,  Matsumoto Naoya (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido) ,  Hashimoto Ryuichi (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido) ,  Endo Tetsuya (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido) ,  Maeda Hayato (Faculty of Agriculture and Life Science, Hirosaki University) ,  Hamada Junichi (Cancer Prevention Laboratories, Health Sciences University of Hokkaido) ,  Hamada Junichi (School of Nursing and Social Services, Health Sciences University of Hokkaido) ,  Osada Kazumi (School of Dentistry, Health Sciences University of Hokkaido) ,  Miyashita Kazuo (Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University) ,  Mutoh Michihiro (Epidemiology and Preventions Group, Center for Public Health Sciences, National Cancer Center)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 64  Issue： 1  Page： 52-58(J-STAGE)  Publication year： 2019 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *stem cell ,...
Semi thesaurus term： *結腸直腸癌幹細胞 ,...

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Author keywords (5)： fucoxanthin ,  carotenoid ,  colorectal cancer stem cell ,  metabolite ,  xenograft mice

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Experimental treatment for tumors  (GE02040Y)

Substance index (3)： Fucoxanthin ,  Fucoxanthinol ,  Glycine

Reference (34)：

• 1 Satomi Y. Antitumor and cancer-preventive function of fucoxanthin: a marine carotenoid. Anticancer Res 2017; 37: 1557-1562.
• 2 Mei C, Zhou S, Zhu L, Ming J, Zeng F, Xu R. Antitumor effects of Laminaria extract fucoxanthin on lung cancer. Mar Drugs 2017; 15: 39.
• 3 Beppu F, Niwano Y, Tsukui T, Hosokawa M, Miyashita K. Single and repeated oral dose toxicity study of fucoxanthin (FX), a marine carotenoid, in mice. J Toxicol Sci 2009; 34: 501-510.
• 4 Iio K, Okada Y, Ishikura M. Single and 13-week oral toxicity study of fucoxanthin oil from microalgae in rats. Shokuhin Eiseigaku Zasshi 2011; 52: 183-189 (in Japanese).
• 5 Asai A, Yonekura L, Nagao A. Low bioavailability of dietary epoxyxanthophylls in humans. Br J Nutr 2008; 100: 273-277.

Terms in the title (8)： フコキサンチン ,  投与 ,  グリシン ,  腫瘍 ,  予測因子 ,  異種移植 ,  マウス ,  遅延