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J-GLOBAL ID：201902286201585401   Reference number：19A0148861

Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells

患者由来癌関連線維芽細胞から分泌されるピルビン酸は原発性リンパ腫細胞の生存を支持する

Author (12)： Sakamoto Akihiko (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Sakamoto Akihiko (Department of Mechanism of Aging, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Kunou Shunsuke (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Shimada Kazuyuki (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Shimada Kazuyuki (Institute for Advanced Research, Nagoya University, Nagoya, Japan) ,  Tsunoda Makoto (Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan) ,  Aoki Tomohiro (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Iriyama Chisako (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Tomita Akihiro (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Nakamura Shigeo (Department of Pathology and Clinical Laboratories, Nagoya University Hospital, Nagoya, Japan) ,  Hayakawa Fumihiko (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Kiyoi Hitoshi (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 110  Issue： 1  Page： 269-278  Publication year： 2019 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *fibroblast ,...
Semi thesaurus term： *Cancer-Associated Fibroblasts ,...

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Author keywords (5)： cancer-associated fibroblast ,  Krebs cycle ,  lymphoma ,  pyruvate ,  reverse Warburg effect

JST classification (2)： Blood cell tumors(=neoplasms)  (GK04000M) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (2)： Pyruvic Acid ,  Citric acid

Terms in the title (9)： 患者 ,  癌関連線維芽細胞 ,  分泌 ,  ピルビン酸 ,  原発 ,  リンパ腫 ,  細胞 ,  生存 ,  支持