Art

J-GLOBAL ID：202002248745373391   Reference number：20A0885253

Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate

臭素酸カリウムの経口投与により誘導されるGPTデルタマウスの小腸における酸化ストレス駆動変異誘発【JST・京大機械翻訳】

Author (10)： Aoki Yasunobu (National Institute for Environmental Studies, Center for Health and Environmental Risk Research, Onogawa, Tsukuba, Ibaraki 305-8506, Japan) ,  Taniguchi Yosuke (Kyushu University, Graduate School of Pharmaceutical Sciences, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan) ,  Matsumoto Michiyo (National Institute for Environmental Studies, Center for Health and Environmental Risk Research, Onogawa, Tsukuba, Ibaraki 305-8506, Japan) ,  Matsumoto Michi (National Institute for Environmental Studies, Center for Health and Environmental Risk Research, Onogawa, Tsukuba, Ibaraki 305-8506, Japan) ,  Ohno Mizuki (Kyushu University, Faculty of Medical Sciences, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan) ,  Masumura Kenichi (National Institute of Health Sciences, Division of Genetics and Mutagenesis, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan) ,  Sasaki Shigeki (Kyushu University, Graduate School of Pharmaceutical Sciences, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan) ,  Tsuzuki Teruhisa (Kyushu University, Faculty of Medical Sciences, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan) ,  Yamamoto Masayuki (Tohoku University, Graduate School of Medicine, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan) ,  Nohmi Takehiko (National Institute of Health Sciences, Division of Genetics and Mutagenesis, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan)
Material： Mutation Research. Genetic Toxicology and Environmental Mutagenesis  (Mutat Res Genet Toxicol Environ Mutagen)
Volume： 850-851  Page： Null  Publication year： 2020 
JST Material Number： W2380A  ISSN： 1383-5718  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Tumorigenesis induced by oxida...

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Thesaurus term： tumorigenesis ,  nucleotide ,  *mutagenesis ,  tumor ,  agent ,  oncogene ,  site-directed mutagenesis ,  *small intestine ,  *oxidative stress ,  transgenic mouse ,  DNA ,  mutation ,  *oxidation ,  nitrogen heterocyclic compound ,  hydroxy compound
Semi thesaurus term： 残基 , 【Automatic Indexing@JST】

Author keywords (5)： In vivo mutation ,  Nrf2-knockout ,  Site-specific mutation ,  Threshold ,  Transgenic mouse assay

JST classification (2)： Carcinogenic mechanisms and factors  (GE02020C) ,  Genetic variation  (EC01030Y)

Substance index (1)： Guanine

Terms in the title (9)： 臭素酸カリウム ,  経口投与 ,  誘導 ,  GPT ,  デルタ ,  マウス ,  小腸 ,  酸化ストレス ,  変異誘発