Art

J-GLOBAL ID：202002277652355368   Reference number：20A0716950

Recapitulating the human segmentation clock with pluripotent stem cells

多能性幹細胞でヒトの分節時計を再現

Author (32)： MATSUDA Mitsuhiro (Lab. for Reconstitutive Developmental Biology, RIKEN Center for Biosystems Dynamics Res. (RIKEN BDR), Kobe, JPN) ,  EBISUYA Miki (Lab. for Reconstitutive Developmental Biology, RIKEN Center for Biosystems Dynamics Res. (RIKEN BDR), Kobe, JPN) ,  MATSUDA Mitsuhiro (European Molecular Biology Lab. (EMBL) Barcelona, Barcelona, ESP) ,  EBISUYA Miki (European Molecular Biology Lab. (EMBL) Barcelona, Barcelona, ESP) ,  YAMANAKA Yoshihiro (Dep. of Cell Growth and Differentiation, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  UEMURA Maya (Dep. of Cell Growth and Differentiation, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  YOSHITOMI Hiroyuki (Dep. of Cell Growth and Differentiation, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  TOGUCHIDA Junya (Dep. of Cell Growth and Differentiation, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  ALEV Cantas (Dep. of Cell Growth and Differentiation, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  YAMANAKA Yoshihiro (Inst. for the Advanced Study of Human Biology (ASHBi), Kyoto Univ., Kyoto, JPN) ,  YAMAMOTO Takuya (Inst. for the Advanced Study of Human Biology (ASHBi), Kyoto Univ., Kyoto, JPN) ,  ALEV Cantas (Inst. for the Advanced Study of Human Biology (ASHBi), Kyoto Univ., Kyoto, JPN) ,  UEMURA Maya (Dep. of Regeneration Sci. and Engineering, Inst. for Frontier Life and Medical Sci., Kyoto Univ., Kyoto, JPN) ,  NISHIO Megumi (Dep. of Regeneration Sci. and Engineering, Inst. for Frontier Life and Medical Sci., Kyoto Univ., Kyoto, JPN) ,  YOSHITOMI Hiroyuki (Dep. of Regeneration Sci. and Engineering, Inst. for Frontier Life and Medical Sci., Kyoto Univ., Kyoto, JPN) ,  TOGUCHIDA Junya (Dep. of Regeneration Sci. and Engineering, Inst. for Frontier Life and Medical Sci., Kyoto Univ., Kyoto, JPN) ,  OSAWA Mitsujiro (Dep. of Clinical Application, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  SAITO Megumu K. (Dep. of Clinical Application, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  NAGAHASHI Ayako (Dep. of Clinical Application, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  GUO Long (Lab. for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sci. (RIKEN IMS), Tokyo, JPN) ,  IKEGAWA Shiro (Lab. for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sci. (RIKEN IMS), Tokyo, JPN) ,  SAKURAI Satoko (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  MAURISSEN Thomas L. (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  NAKAMURA Michiko (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  MATSUMOTO Tomoko (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  IKEYA Makoto (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  YAMAMOTO Takuya (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  WOLTJEN Knut (Dep. of Life Sci. Frontiers, Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  KIHARA Shunsuke (Dep. of Fundamental Cell Technol., Center for iPS Cell Res. and Application (CiRA), Kyoto Univ., Kyoto, JPN) ,  KAWAKAMI Noriaki (Dep. of Orthopedics and Spine Surgery, Meijo Hospital, Nagoya, JPN) ,  YAMAMOTO Takuya (AMED-CREST, AMED 1-7-1 Otemachi, Chiyodaku, Tokyo, JPN) ,  YAMAMOTO Takuya (Medical-Risk Avoidance Based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto, JPN)
Material： Nature (London)  (Nature (Lond))
Volume： 580  Issue： 7801  Page： 124-129  Publication year： Apr. 02, 2020 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： cell differentiation ,  in vitro experiment ,  mesoderm ,  vertebral column ,  *pluripotent stem cell ,  embryogenesis ,  Vertebrata ,  *human(primates) ,  gene ,  gene expression ,  pattern formation
Semi thesaurus term： Cas9 ,  細胞系譜 ,  器官形成 ,  *分節時計 , 【Automatic Indexing@JST】

JST classification (1)： Development(=generation)and differentiation  (EJ16020W)

Terms in the title (3)： 多能性幹細胞 ,  ヒト ,  分節時計