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J-GLOBAL ID:202101011674007197   Update date: Mar. 05, 2025

TANAKA SHIGERU

タナカ シゲル | TANAKA SHIGERU
Affiliation and department:
Research field  (3): Neurology ,  Pharmacology ,  Neuroscience - general
Research keywords  (7): GPCR ,  神経軸索再生 ,  neuronal protection ,  stroke ,  緑内障 ,  神経細胞分化 ,  autophagy
Research theme for competitive and other funds  (12):
  • 2021 - 2024 軸索・シナプス修飾因子GPR3を用いた中枢神経障害後の神経回路再構築療法への応用
  • 2019 - 2022 Identification of novel ER stress relieving drugs using a high-content microscope and application to therapeutic development
  • 2018 - 2021 The expression of G protein-coupled receptor 3 modulates presynaptic function in differentiated PC12 cells
  • 2016 - 2019 Identification and application of novel chaperone mechanism using C-terminal deficient serotonin transporter as a sensor
  • 2016 - 2019 Screening and application of drugs that facilitate membrane trafficking in order to overcome ER stress-related diseases
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Papers (63):
  • Ishii, Tomomi, Kajimoto, Taketoshi, Kikkawa, Satoshi, Narasaki, Soshi, Noguchi, Soma, Imamura, Serika, Harada, Kana, Hide, Izumi, Tanaka, Shigeru, Tsutsumi, Yasuo M., et al. Protein kinase C (PKC) inhibitor Calphostin C activates PKC in a light-dependent manner at high concentrations via the production of singlet oxygen. EUROPEAN JOURNAL OF PHARMACOLOGY. 2024. 984
  • Noguchi, Soma, Kajimoto, Taketoshi, Kumamoto, Takuya, Shingai, Masashi, Narasaki, Soshi, Urabe, Tomoaki, Imamura, Serika, Harada, Kana, Hide, Izumi, Tanaka, Sigeru, et al. Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells. FRONTIERS IN PHARMACOLOGY. 2023. 14
  • Narasaki, Soshi, Noguchi, Soma, Urabe, Tomoaki, Harada, Kana, Hide, Izumi, Tanaka, Shigeru, Yanase, Yuhki, Kajimoto, Taketoshi, Uchida, Kazue, Tsutsumi, Yasuo M., et al. Identification of protein kinase C domains involved in its translocation induced by propofol. EUROPEAN JOURNAL OF PHARMACOLOGY. 2023. 955
  • Hide, Izumi, Shiraki, Hiroko, Masuda, Akihiro, Maeda, Takuya, Kumagai, Mayuka, Kunishige, Nao, Yanase, Yuhki, Harada, Kana, Tanaka, Shigeru, Sakai, Norio. P2Y2 receptor mediates dying cell removal via inflammatory activated microglia. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2023. 153. 1. 55-67
  • Kana Harada, Ryoma Sho, Hiromiki Takakura, Eri Yokoyama, Reika Koyama, Yuka Yamamoto, Naoko Adachi, Shigeru Tanaka, Izumi Hide, Norio Sakai. S-Palmitoylation of the serotonin transporter promotes its cell surface expression and serotonin uptake. Biochemical and biophysical research communications. 2023. 662. 58-65
more...
MISC (27):
  • 田中 茂, 嶋田 直人, 宮城 達博, 白榊 紘子, 秀 和泉, 白藤 俊彦, 酒井 規雄. 海馬神経細胞において内在性に発現するGPR3が神経極性形成に与える影響. 生命科学系学会合同年次大会. 2017. 2017年度. [2P-1153]
  • 宇野 珠世, 田中 茂, 宮城 達博, 秀 和泉, 白藤 俊彦, 酒井 規雄, 入舩 正浩. cAMPによるα3α5型ニコチン受容体機能の調整. 広島大学歯学雑誌. 2016. 48. 1. 84-84
  • 田中 茂, 土肥 栄祐, 酒井 規雄. 【最新臨床脳卒中学[上]-最新の診断と治療-】 病態生理 虚血による神経障害の分子メカニズム オートファジー. 日本臨床. 2014. 72. 増刊5 最新臨床脳卒中学(上). 106-110
  • Shigeru Tanaka, Tatsuhiro Miyagi, Izumi Hide, Toshihiko Shirafuji, E. Antonio Chiocca, Norio Sakai. The expression of GPR3 protects cerebellar granular neurons from various apoptotic stimuli. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 113P-113P
  • Izumi Hide, Mayumi Kamigaki, Yuhki Yanase, Takahiro Seki, Shigeru Tanaka, Toshihiko Shirafuji, Michihiro Hide, Norio Sakai. Modulation of microglial function by TLR4-mediated adenosine A2a receptor activation. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 211P-211P
more...
Books (2):
  • On studying pathophysiology og stroke
    2018
  • 最新臨床脳卒中学
    日本臨床 2014
Association Membership(s) (10):
The Molecular Biology Society of Japan ,  The Japan Academy of Neurosonology ,  日本神経学会 ,  日本内科学会 ,  日本脳循環代謝学会 ,  日本脳卒中学会 ,  日本神経化学学会 ,  Society for Neuroscience ,  日本神経科学学会 ,  日本薬理学会
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