いぶらひむ ひっしゃむ らどわん

• 2006 - 2008 遺伝子工学的手法による新規の医薬品剤としてヒトリゾチームの抗菌ペプチドの生産開発
• 2001 - 2003 リゾチームおよびα-ラクトアルブミンの抗菌戦略
• リゾチームの機能性ペプチド
• 機能性食品ペプチド
• 鳥卵の抗菌システム
オボトランスフェリンの構造と生理機能の解明
Potential Antimicrobial strategy using Genetically Engineered Dimer of α-lactalbumin, and lysozyme.
Antimicrobial System of Avian Egg
Structure and Antimicrobial Function of Ovotransferrin.
Genetic and Biochemical Approaches to The Antimicrobial Mechanism of Lysozyme.

• Momoka Obayashi, Momoko Kimura, Asako Haraguchi, Mari Gotanda, Taiki Kitagawa, Misato Matsuno, Kozue Sakao, Daisuke Hamanaka, Kodai Kusakisako, Tomoshi Kameda, et al. Bovine lactoferrin inhibits Plasmodium berghei growth by binding to heme. Scientific reports. 2024. 14. 1. 20344-20344
• Hisham Radwan Ibrahim, Ai Hitotsumatsu, Takeshi Miyata. Identification of potent antioxidant bioactive peptides from the soluble proteins of chicken egg yolk. Functional Food Science. 2023. 3. 6. 63-63
• Takeshi Miyata, Kosuke Minamihata, Koichi Kurihara, Yui Kamizuru, Mari Gotanda, Momoka Obayashi, Taiki Kitagawa, Keita Sato, Momoko Kimura, Kosuke Oyama, et al. Highly efficient protein expression of Plasmodium vivax surface antigen, Pvs25, by silkworm and its biochemical analysis. Protein expression and purification. 2022. 195-196. 106096-106096
• Hisham R. Ibrahim, Ahmed S. Ahmed, Airi Komeda, Takeshi Miyata. Lactophorin in Camel Milk Undergoing Specific Proteolysis and Exhibiting Potent Anticancer Action against Human Colon and Breast Cancer Cells Through ROS Generation. Avicenna Journal of Medical Biochemistry. 2022. 10. 1. 1-12
• Keyu Chen, Yasushi Nakasone, Shuhan Yi, Hisham R Ibrahim, Kozue Sakao, Md Amzad Hossain, De-Xing Hou. Natural Garlic Organosulfur Compounds Prevent Metabolic Disorder of Lipid and Glucose by Increasing Gut Commensal Bacteroides acidifaciens. Journal of agricultural and food chemistry. 2022. 70. 19. 5829-5837

もっと見る

• Keiji Kinoshita, Si Lhyam Myint, Takeshi Shimogiri, Hisham R. Ibrahim, Kotaro Kawabe, Shin Okamoto, Yen-Pei Lee, Yoichi Matsuda, Yoshizane Maeda. Chicken Ovotransferrin Variants OTFB and OTFC Harboring Substitution of GAT (Asp) to AAT (Asn) in the Codon 500 and their Antimicrobial Activity. JOURNAL OF POULTRY SCIENCE. 2016. 53. 4. 257-263
• Hisham R. Ibrahim, Sayuri Tatsumoto, Hajime Ono, Filip Van Immerseel, Ruth Raspoet, Takeshi Miyata. A novel antibiotic-delivery system by using ovotransferrin as targeting molecule. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2015. 66. 59-69
• Hisham R. Ibrahim, Akiko Hozono, Masaharu Fukami, Mohamed A. Shaban, Takeshi Miyata. Expression of Ovotransferrin Enhances Tolerance of Yeast Cells toward Oxidative Stress. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2013. 61. 26. 6358-6365
• Si Lhyam Myint, Keiji Kinoshita, Takeshi Shimogiri, Hisham R. Ibrahim, Tomohiro Tsusaki, Tomomi Tanoue, Kotaro Kawabe, Yoshizane Maeda, Shin Okamoto. Effect of polymorphism in egg white lysozyme on muramidase and antibacterial activities as well as hatchability in the Japanese quail (Coturnix japonica). JOURNAL OF ANIMAL SCIENCE. 2012. 90. 6. 1747-1755
• Hisham R. Ibrahim, Tohru Kiyono. Novel anticancer activity of the autocleaved ovotransferrin against human colon and breast cancer cells. Journal of Agricultural and Food Chemistry. 2009. 57. 23. 11383-11390

もっと見る

• Hen Egg White Lysozyme and Ovotransferrin: Mystery, Structural Role and Antimicrobial Function
  Proceedings of the Xth European Symposium on the Quality of Eggs and Egg Products. Yves Nys (Eds) 2003
• A Bactericidal Domain of Lysozyme with Helix-loop-helix structure Present A Strong Antimicrobial Activity
  Proceedings of the 27th European Peptide Symposium. E. Benedetti and C. Pedone (Eds) 2002
• Ovotransferrin : Chemistry and Antimicrobial Function
  Natural Food Antimicrobial Systems CRC Press Inc. FL, USA 2000
• Protein-Based Biochemical and Genetic Stategies for The Design of New Antimicrobial Agent
  Physicochemical and Biological Functionality of Food Systems Technomic Press Co. Pennsylvania, USA 1999
• Inghts into The Structure-Function Relationships of Ovalbumin, Ovotransferrin, and Lysozyme" : In Hen Eggs-Their Basic and Applied Science
  CRC Press Inc. FL, USA 1997

もっと見る

• 伝染病治療薬としての抗菌性ペプチドのデザインに関する研究
  1998 - 2001
• Design of Antimicrobial Peptides as Potential Drugs in the Treatment of Infectious Diseases
  1998 - 2001

• - 1993 鳥取大学 生物資源研究科 生化学
• - 1993 鳥取大学
• - 1990 山口大学 生物資源研究科 生化学
• - 1990 山口大学
• - 1979 カイロ大学 農学部 食品化学
- 1979 Cairo University Faculty of Agriculture Food chemistry

• PhD Degree (United Graduate School of Agriculture, Tottori University)
• Ph.D.

• 2000 - 2001 Visiting Scientist, Center for Antimicrobial
• Research, Cal Poly University, USA

• 2008 - 現在 Americal Oil Chemist's Society (AOCS) Hisham Ibrahim
• 2008 - 現在 Americal Chemical Society (ACS) Hisham Ibrahim
• 2005 - 現在 World’s Poultry Science Association (WPSA) Hisham Ibrahim
• 2001 - 現在 Japanese Dairy Science Association ヒッシャム イブラヒム
• 1995 - 現在 International Society of Food Function ヒッシャム イブラヒム
1988 - 現在 日本農芸化学会 ヒッシャム イブラヒム
2009 - American Chemical Society (ACS) Conference Organizer

• 2001 - 2000 Outstanding Intellectuals of the 21^th Century in Structural Biology
• 2001 - 2000 Outstanding Intellectuals of the 21st Century Order of Excellence, in the field of "STRUCTURAL BIOLOGY and ANTIMICROBIAL DRUGS"

American Chemical Society (ACS) ,  American Oil Chemists Society (AOCS) ,  Japanese Dairy Science Association ,  Institute of Food Technologists(IFT) ,  Food System Functionality Association (FSFA) ,  日本農芸化学会 ,  Egg Science Forum ,  Japanese Dairy Science Association ,  and Agrochemistry ,  Biotechnology ,  Japan Society for Bioscience ,  American Oil Chemists Society (AOCS) ,  World Poultry Science Association