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競争的資金等の研究課題 (14件)：
論文 (27件)：
MISC (13件)：
特許 (2件)：
Works (2件)：
学歴 (2件)：
学位 (1件)：
経歴 (8件)：
受賞 (2件)：
所属学会 (8件)：
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- 2001 - 2002 高度好熱菌MutM蛋白質を用いた活性酸素障害DNA塩基除去修復機構の解析
- 2001 - 構造ゲノム科学に対応したX線結晶構造解析を大規模かつ迅速に行うための全自動化に向けたハードおよびソフトの概念設計および新しい技術の開発
- 2001 - 蛋白質などの生体高分子のX線結晶学を手法とし、3次元立体構造に基づき蛋白質の機能を解明する構造生物学研究
- 2001 - Development of new technique and conceptual design of hardware and software toward full-automation to execute the determination of x-ray crystal structure in large and rapidly corresponding to the Structural Genomics.
- 2001 - Structural Biology Research which reveals the function of proteins based on their 3D structures with X-ray crystallograpy of biomacromolecules such as a protein.
全件表示
- Tosha T, Nomura T, Nishida T, Saeki N, Okubayashi K, Yamagiwa R, Sugahara M, Nakane T, Yamashita K, Hirata K, et al. Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nature communications. 2017. 8. 1. 1585-1585
- Nakane T, Hanashima S, Suzuki M, Saiki H, Hayashi T, Kakinouchi K, Sugiyama S, Kawatake S, Matsuoka S, Matsumori N, et al. 5B35: Serial Femtosecond Crystallography (SFX) of Ground State Bacteriorhodopsin Crystallized from Bicelles Determined Using 7-keV X-ray Free Electron Laser (XFEL) at SACLA. Worldwide Protein Data Bank. 2016
- Nakane T, Song C, Suzuki M, Nango E, Kobayashi J, Masuda T, Inoue S, Mizohata E, Nakatsu T, Tanaka T, et al. Native sulfur/chlorine SAD phasing for serial femtosecond crystallography. Acta crystallographica. Section D, Biological crystallography. 2015. 71. Pt 12. 2519-2525
- Yamashita K, Pan D, Okuda T, Sugahara M, Kodan A, Yamaguchi T, Murai T, Gomi K, Kajiyama N, Mizohata E, et al. An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Scientific reports. 2015. 5. 14017
- Yamashita K, Pan D, Okuda T, Sugahara M, Kodan A, Yamaguchi T, Murai T, Gomi K, Kajiyama N, Mizohata E, et al. Luciferin-regenerating enzyme solved by SIRAS using XFEL (refined against Hg derivative data). Worldwide Protein Data Bank. 2015
- Michihiro Sugahara, Yukuhiko Asada, Katsumi Shimizu, Hitoshi Yamamoto, Neratur K Lokanath, Hisashi Mizutani, Bagautdin Bagautdinov, Yoshinori Matsuura, Midori Taketa, Yuichi Kageyama, et al. High-throughput crystallization-to-structure pipeline at RIKEN SPring-8 Center. Journal of structural and functional genomics. 2008. 9. 1-4. 21-8
- Asada Yukuhiko, Sawano Masahide, Ogasahara Kyoko, NAKAMURA Junji, OTA Motonori, KUROISHI Chizu, SUGAHARA Mitsuaki, YUTANI Katsuhide, KUNISHIMA Naoki. Stabilization Mechanism of the Tryptophan Synthase α-Subunit from Thermus thermophilus HB8 : X-Ray Crystallographic Analysis and Calorimetry. The journal of biochemistry. 2005. 138. 4. 343-353
- Taka Junichiro, Ogasahara Kyoko, Jeyakanthan Jeyaraman, KUNISHIMA Naoki, KUROISHI Chizu, SUGAHARA Mitsuaki, YOKOYAMA Shigeyuki, YUTANI Katsuhide. Stabilization Due to Dimer Formation of Phosphoribosyl Anthranilate Isomerase from Thermus thermophilus HB8 : X-Ray Analysis and DSC Experiments. The journal of biochemistry. 2005. 137. 5. 569-578
- NK Lokanath, Shiromizu, I, N Ohshima, Y Nodake, M Sugahara, S Yokoyama, S Kuramitsu, M Miyano, N Kunishima. Structure of aldolase from Thermus thermophilus HB8 showing the contribution of oligomeric state to thermostability. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2004. 60. 1816-1823
- Y Hisanaga, H Ago, N Nakagawa, K Hamada, K Ida, M Yamamoto, T Hori, Y Arii, M Sugahara, S Kuramitsu, et al. Structural basis of the substrate-specific two-step catalysis of long chain fatty acyl-CoA synthetase dimer. JOURNAL OF BIOLOGICAL CHEMISTRY. 2004. 279. 30. 31717-31726
- タンパク質等の結晶化方法及び装置
- METHOD AND APPARATUS FOR CRYSTALLIZATION OF PROTEINS
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大規模蛋白質立体構造解析全自動結晶化観察システムの開発等
2002 - -
Development of full-automatic protein crystallization and observation system for the determination of protein three dimensional structure
2002 -
- - 2000 大阪大学 理学研究科 生物科学
- - 2000 大阪大学
- 博士(理学)
- 2003 - 理化学研究所ハイスループットファクトリー チームリーダー(兼任)
- 2003 - 特定国立研究開発法人理化学研究所
- 2002 - 理化学研究所構造生物物理研究室 研究員
- 2002 - 特定国立研究開発法人理化学研究所
- 2000 - 理化学研究所構造生物物理研究室 基礎科学特別研究員
全件表示
- 2000 - JB論文賞
- 2000 - JB Award
日本放射光学会
, 日本生化学会
, 日本分子生物学会
, 日本結晶学会
, The Japanese Society for Synchrotron Radiation Research
, the Japanese Biochemical Society
, The Molecular Biology Society of Japan
, The Crystallographic Society of Japan
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