落合恭子

オチアイキョウコ | Ochiai Kyoko

所属機関・部署：
職名：助教
ホームページURL (1件)： http://www.biochem.med.tohoku.ac.jp/members/index.html

研究分野 (2件)：免疫学 , 医化学

研究キーワード (7件)：クロマチン制御 , B細胞分化制御 , 受容体シグナル伝達 , 遺伝子発現ネットワーク , エピゲノム , 転写因子 , 細胞分化

競争的資金等の研究課題 (6件)：

全件表示

論文 (29件)：

Kyoko Ochiai, Hiroki Shima, Toru Tamahara, Nao Sugie, Ryo Funayama, Keiko Nakayama, Tomohiro Kurosaki, Kazuhiko Igarashi. Accelerated plasma-cell differentiation in Bach2-deficient mouse B cells is caused by altered IRF4 functions. The EMBO journal. 2024
Liang Liu, Mitsuyo Matsumoto, Miki Watanabe-Matsui, Tadashi Nakagawa, Yuko Nagasawa, Jingyao Pang, Bert K K Callens, Akihiko Muto, Kyoko Ochiai, Hirotaka Takekawa, et al. TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. International journal of molecular sciences. 2024. 25. 8
Kyoko Ochiai, Kazuhiko Igarashi. Exploring novel functions of BACH2 in the acquisition of antigen-specific antibodies. International immunology. 2023. 35. 6. 257-265
Liang Liu, Mitsuyo Matsumoto, Miki Matsui-Watanabe, Kyoko Ochiai, Bert K K Callens, Long Chi Nguyen, Yushi Kozuki, Miho Tanaka, Hironari Nishizawa, Kazuhiko Igarashi. BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin. Antioxidants (Basel, Switzerland). 2022. 11. 8
Kyoko Ochiai, Hiroki Shima, Tsuyoshi Ikura, Marissa C Franke, Evelyn P Sievert, Roger Sciammas, Kazuhiko Igarashi. Protocol for in vitro BCR-mediated plasma cell differentiation and purification of chromatin-associated proteins. STAR protocols. 2021. 2. 3. 100633-100633

MISC (14件)：

講演・口頭発表等 (8件)：

転写因子とクロマチン制御因子による細胞分化制御の遺伝子発現ネットワーク
(第42回日本分子生物学会年会 2019)
転写因子結合DNAモチーフの多様性が制御する細胞分化
(第41回日本分子生物学会年会 2018)
The diversity of IRF4 DNA binding motifs governs cell fate during plasma cell differentiation
(7th Meeting of the Asian Forum of Chromosome and Chromatin Biology 2018)
Gene regulatory networks of B-to-plasma cell differentiation orchestrated by IRF4 and its partner transcription factors
(第46回日本免疫学会学術集会 2017)
Gene Regulatory Networks Composed by Transcription Factors Orchestrate Plasma Cell Differentiation
(The 2017 Japan-NIH Joint Symposium on Advances in Biomedical Research and Disease 2017)

学歴 (2件)：

学位 (1件)：

経歴 (4件)：

受賞 (1件)：

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落合 恭子