比嘉綱己

Higa Tsunaki

所属機関・部署：

研究分野 (1件)：発生生物学

競争的資金等の研究課題 (3件)：

論文 (10件)：

Tsunaki Higa, Keiichi I Nakayama. Cell cycle heterogeneity and plasticity of colorectal cancer stem cells. Cancer science. 2024
Takeru Oka, Tsunaki Higa, Osamu Sugahara, Daisuke Koga, Shogo Nakayama, Keiichi I Nakayama. Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence After Chemotherapy of Intestinal Tumors. Cancer research. 2023
Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shogo Nakayama, Takeru Oka, Osamu Sugahara, Daisuke Koga, Shoichiro Takeishi, Hirokazu Nakatsumi, Naoki Hosen, et al. Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium. Nature communications. 2022. 13. 1. 1500-1500
Hirokazu Nakatsumi, Takeru Oka, Tsunaki Higa, Michiko Shirane, Keiichi I Nakayama. Nuclear-cytoplasmic shuttling protein PP2AB56 contributes to mTORC1-dependent dephosphorylation of FOXK1. Genes to cells : devoted to molecular & cellular mechanisms. 2018. 23. 7. 599-605
Takahiro Horinouchi, Akimasa Hoshi, Takuya Harada, Tsunaki Higa, Sarita Karki, Koji Terada, Tsunehito Higashi, Yosuke Mai, Prabha Nepal, Yuichi Mazaki, et al. Endothelin-1 suppresses insulin-stimulated Akt phosphorylation and glucose uptake via GPCR kinase 2 in skeletal muscle cells. British journal of pharmacology. 2016. 173. 6. 1018-32

MISC (7件)：

Akimasa Hoshi, Takahiro Horinouchi, Takuya Harada, Tsunaki Higa, Tsunehito Higashi, Koji Terada, Yosuke Mai, Prabha Nepal, Mika Horiguchi, Chizuru Hatate, et al. Cell signaling mechanism activated by endothelin-1 in rat skeletal muscle cells. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 93P-93P
Takahiro Horinouchi, Tsunehito Higashi, Koji Terada, Tsunaki Higa, Yosuke Mai, Chizuru Hatate, Prabha Nepal, Mika Horiguchi, Takuya Harada, Soichi Miwa. Identification and characterization of STIM1L, a novel splice variant of STIM1. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 91P-91P
Takahiro Horinouchi, Tsunaki Higa, Hiroyuki Aoyagi, Koji Terada, Tadashi Nishiya, Soichi Miwa. Negative regulation of endothelin type A receptor-operated TRPC6 by PKA phosphorylation. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 211P-211P
Tsunaki Higa, Takahiro Horinouchi, Hiroyuki Aoyagi, Koji Terada, Tadashi Nishiya, Soichi Miwa. Regulatory mechanism of endothelin type A receptor-operated Ca2+ entry via TRPC3 and TRPC6 channels. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 211P-211P
Takahiro Horinouchi, Tsunaki Higa, Tadashi Nishiya, Hiroyuki Aoyagi, Hiroyuki Suzuki, Arata Nishimoto, Soichi Miwa. Negative regulation of endothelin type A receptor-operated TRPC6 by adenylate cyclase/cAMP/PKA pathway. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 112P-112P

講演・口頭発表等 (6件)：

Tracing intestinal p57 + cells uncovers spatiotemporal reprogramming of regenerating epithelium and the identity of cancer stem cells
(The 41st Sapporo International Cancer Symposium 2023)
p57 陽性幹細胞は腸管上皮の再生と腫瘍の基盤となる
(日本細胞生物学会第75 回大会 2023)
Tracing intestinal p57+ cells uncovers spatiotemporal reprogramming of regenerating epithelium and the identity of cancer stem cells.
(第20 回幹細胞シンポジウム 2023)
p57 陽性タフト細胞は胃底腺幹細胞として機能する
(第45 回日本分子生物学会年会 2022)
Tracing p57+ cells uncovers spatiotemporal reprogramming of differentiated cells underlying regeneration and neoplasia in the intestinal epithelium
(第44 回日本分子生物学会年会 2021)

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比嘉 綱己