2023 - 2025 Study of clinically over-expressed and chimeric RND multidrug efflux pumps from Acinetobacter baumannii and Pseudomonas aeruginosa
2022 - 2023 病原性細菌の多剤排出ポンプの解明と阻害剤の開発
2022 - 2023 多剤耐性アシネトバクターの薬剤排出ポンプの創薬標的としての検証
2020 - 2023 Characterization of unstudied RND-type multidrug efflux pumps from pathogenic microorganisms
2018 - 2020 Mechanism, evolution and regulation of multidrug resistance
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論文 (18件):
S. Yamasaki, N. Koga, T. Hosomi, M. Zwama, C. Jirayupa, T. Yanagida, K. Nishino. Development of a bacterial release compound assay for prevention and early detection of bacteria-derived diseases. Medical Science Digest. 2024. 50. 41-43
Seiji Yamasaki, Martijn Zwama, Tomohiro Yoneda, Mitsuko Hayashi-Nishino, Kunihiko Nishino. Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosa. 2023. 169. 6
Martijn Zwama. Function and mechanism of multidrug efflux transporters: crystallography and biochemical studies on RND transporter AcrB. Osaka University. 2018