チャンレンチエン

チャンレンチエン | Chang Jen-Chien

所属機関・部署：
職名：研究員

研究分野 (6件)：ゲノム生物学 , 分子生物学 , 生物物理、化学物理、ソフトマターの物理 , ナノバイオサイエンス , 遺伝学 , 生物物理学

研究キーワード (9件)：転写 , ヌクレオソーム , エピジェネティクス , 一分子イメージング , 生命情報科学 , ヒストン修飾 , 1分子計測 , クロマチン , エピゲノム

競争的資金等の研究課題 (1件)：

2017 - 2019 Detecting combinatorial histone modification dynamics at single nucleosome resolution for key genes in Epithelial-Mesenchymal-Transition

論文 (11件)：

Jonathan Moody, Tsukasa Kouno, Miki Kojima, Ikuko Koya, Julio Leon, Akari Suzuki, Akira Hasegawa, Taishin Akiyama, Nobuko Akiyama, Masayuki Amagai, et al. A single-cell atlas of transcribedcis-regulatory elements in the human genome. 2023
Nando D Das, Jen-Chien Chang, Chung-Chau Hon, S Thomas Kelly, Shinsuke Ito, Marina Lizio, Bogumil Kaczkowski, Hisami Watanabe, Keisuke Katsushima, Atsushi Natsume, et al. Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties. BMC genomics. 2023. 24. 1. 574-574
Chi Wai Yip, Chung-Chau Hon, Kayoko Yasuzawa, Divya M. Sivaraman, Jordan A. Ramilowski, Youtaro Shibayama, Saumya Agrawal, Anika V. Prabhu, Callum Parr, Jessica Severin, et al. Antisense-oligonucleotide-mediated perturbation of long non-coding RNA reveals functional features in stem cells and across cell types. Cell Reports. 2022. 41. 13. 111893-111893
Jonathan Moody, Tsukasa Kouno, Jen-Chien Chang, Yoshinari Ando, Piero Carninci, Jay W Shin, Chung-Chau Hon. SCAFE: a software suite for analysis of transcribed cis-regulatory elements in single cells. Bioinformatics. 2022. 38. 22. 5126-5128
Jordan A Ramilowski, Chi Wai Yip, Saumya Agrawal, Jen-Chien Chang, Yari Ciani, Ivan V Kulakovskiy, Mickaël Mendez, Jasmine Li Ching Ooi, John F Ouyang, Nick Parkinson, et al. Functional annotation of human long noncoding RNAs via molecular phenotyping. Genome research. 2020. 30. 7. 1060-1072

MISC (6件)：

Jen-Chien Chang, Kazuhide Watanabe, Takashi Umehara, Yuichi Taniguchi, Yuko Sato, Hiroshi Kimura, Akiko Minoda. Mapping Combinatorial Epigenetic Modifications at Single Nucleosome Resolution. Biophysical Journal. 2018. 114. 3. 254a-254a
Jen-Chien Chang, Takashi Umehara, Keisuke Fujita, Yuichi Taniguchi, Toshio Yanagida, Akiko Minoda. Single-Molecule Analysis of Colocalized Epigenetic Modifications. BIOPHYSICAL JOURNAL. 2016. 110. 3. 66A-66A
Jen-Chien Chang, Michel de Messieres, Ping-Chun Li, Olga I. Kulaeva, Vasily M. Studitsky, Edward T. Yu, Arthur La Porta. Mechanical Stability of Mononucleosome Revealed by Optical Torque Wrench. BIOPHYSICAL JOURNAL. 2013. 104. 2. 580A-580A
Michel de Messieres, Jen-Chien Chang, Ashton T. Belew, Arturas Meskauskas, Jonathan D. Dinman, Arthur La Porta. Single-Molecule Optical Trap Study of Human CCR5 mRNA Structure. BIOPHYSICAL JOURNAL. 2012. 102. 3. 384A-384A
Jen-Chien Chang, Michel de Messieres, Olga I. Kulaeva, Vasily M. Studitsky, Arthur La Porta. Single-Molecule Twist and Stretch of Mononucleosome using Optical Torque Wrench. BIOPHYSICAL JOURNAL. 2012. 102. 3. 481A-481A

書籍 (1件)：

学歴 (2件)：

学位 (1件)：

経歴 (3件)：

所属学会 (2件)：

日本分子生物学会 , 日本生物物理学会

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チャン レンチエン