西宗裕史

ニシムネヒロシ | Nishimune Hiroshi

所属機関・部署：
職名：研究部長
ホームページURL (2件)： https://www.tmghig.jp/research/team/roukanou-shinkeikagaku/roukashinkei/ , https://www.tmig.or.jp/eresearch/a34.html

研究分野 (4件)：神経科学一般 , 神経形態学 , 病態神経科学 , リハビリテーション科学

研究キーワード (10件)：神経科学 , 神経筋接合部 , シナプス , アクティブゾーン , ミトコンドリア , 老化 , 筋萎縮性側索硬化症 , ALS , 間葉系幹細胞 , 超解像顕微鏡

競争的資金等の研究課題 (15件)：

2020 - 2023 シナプス分化因子と間葉系幹細胞によるALS神経変性の抑制メカニズムの解析
2017 - 2022 Center for Biomedical Research Excellence (COBRE) Phase 3: Molecular Regulation of Cell Development and Differentiation
2019 - 2020 Super resolution microscope for the imaging core facility
2018 - 2020 Human mesenchymal stem cells ameliorate symptoms of als model mice
2015 - 2020 Exercise-activated mechanisms reduce degeneration of aged neuromuscular junctions

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論文 (45件)：

Ritsuko Inoue, Hiroshi Nishimune. Neuronal Plasticity and Age-Related Functional Decline in the Motor Cortex. Cells. 2023. 12. 17
Ritsuko Inoue, Masami Miura, Shuichi Yanai, Hiroshi Nishimune. Coenzyme Q10 supplementation improves the motor function of middle-aged mice by restoring the neuronal activity of the motor cortex. Scientific reports. 2023. 13. 1. 4323-4323
Kenji Takikawa, Hiroshi Nishimune. Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses. Biomolecules. 2022. 12. 2
Hiroshi Nishimune, Kimberly G Stanford, Jie Chen, James D Odum, Alexander D Rorie, Robert S Rogers, Joshua L Wheatley, Paige C Geiger, John A Stanford. Forelimb Resistance Exercise Protects Against Neuromuscular Junction Denervation in the SOD1-G93A Rat Model of ALS. Degenerative neurological and neuromuscular disease. 2022. 12. 145-155
Sudheer K Tungtur, Heather M Wilkins, Robert S Rogers, Yomna Badawi, Jessica M Sage, Abdulbaki Agbas, Omar Jawdat, Richard J Barohn, Russell H Swerdlow, Hiroshi Nishimune. Oxaloacetate treatment preserves motor function in SOD1G93A mice and normalizes select neuroinflammation-related parameters in the spinal cord. Scientific reports. 2021. 11. 1. 11051-11051

MISC (6件)：

H. Nishimune, S. Mori, Y. Badawi, K. Shigemoto. SUPER RESOLUTION MICROSCOPY ANALYSIS OF NMJ ACTIVE ZONES IN ADULT AND AGED MICE. MUSCLE & NERVE. 2015. 52. S137-S137
Hiroshi Nishimune, John Stanford, Sudheer Tungtur, Kimberly Stanford. RESISTANCE EXERCISE AMELIORATES NEUROMUSCULAR JUNCTION DENERVATION IN AGING BY INCREASING THE ACTIVE ZONE ORGANIZERS. MUSCLE & NERVE. 2015. 52. S31-S31
Takafumi Mizushige, Katsuya Okawa, Hiroshi Nishimune. Voltage-gated calcium channels [VGCC] interact with cell surface ATP synthase to induce presynaptic differentiation in the brain. NEUROSCIENCE RESEARCH. 2009. 65. S78-S79
Hiroshi Nishimune, Jeff H. Miner, Joshua R. Sanes. A role for laminin in postsynaptic differentiation at the neuromuscular junction. NEUROSCIENCE RESEARCH. 2007. 58. S43-S43
植田淳子, 福井巌, Mony Simo Wydiastuti, 藤森一浩, 西宗裕史, 清末和之, 葛西道生, 田口隆久. 神経突起伸長活性を示す新規蛋白質の解析. 日本分子生物学会年会プログラム・講演要旨集. 1998. 21. 645-645

学歴 (2件)：

学位 (1件)：

経歴 (9件)：

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西宗 裕史