研究者
J-GLOBAL ID:202201017986403826   更新日: 2024年11月17日

若林 繁夫

ワカバヤシ シゲオ | Wakabayashi Shigeo
所属機関・部署:
職名: 特任教授
競争的資金等の研究課題 (31件):
  • 2017 - 2020 iPSC由来心筋細胞を用いた心機能と病態に関与する新規遺伝子の探索と機能解析
  • 2015 - 2018 カルシウムシグナル調節を介した新規代謝制御機構の解明
  • 2015 - 2017 Ca2+負荷モデルマウスで発症する心肥大心不全に対する効果的な薬物運動療法の研究
  • 2014 - 2017 形質膜イオン輸送体近傍から発信する細胞内シグナル増幅機構の解明
  • 2013 - 2016 新たな心肥大調節経路としての核内Ca2+動態とCa2+センサーNCS-1の意義
全件表示
論文 (60件):
  • Hirofumi Morihara, Shunichi Yokoe, Shigeo Wakabayashi, Shinji Takai. TMEM182 inhibits myocardial differentiation of human iPS cells by maintaining the activated state of Wnt/β-catenin signaling through an increase in ILK expression. FASEB BioAdvances. 2024. 6. 11. 565-579
  • Kenjiro Tsuruoka, Shigeo Wakabayashi, Hirofumi Morihara, Ninso Matsunaga, Yasuhito Fujisaka, Isao Goto, Akihisa Imagawa, Michio Asahi. Exacerbation of autoimmune myocarditis by an immune checkpoint inhibitor is dependent on its time of administration in mice. International journal of cardiology. 2020. 313. 67-75
  • Yuko Iwata, Shin Ito, Shigeo Wakabayashi, Masafumi Kitakaze. TRPV2 channel as a possible drug target for the treatment of heart failure. Laboratory investigation; a journal of technical methods and pathology. 2020. 100. 2. 207-217
  • Yuko Iwata, Shigeo Wakabayashi, Shin Ito, Masafumi Kitakaze. Production of TRPV2-targeting functional antibody ameliorating dilated cardiomyopathy and muscular dystrophy in animal models. Laboratory investigation; a journal of technical methods and pathology. 2020. 100. 2. 324-337
  • Shigeo Wakabayashi, Hirofumi Morihara, Shunichi Yokoe, Takatoshi Nakagawa, Kazumasa Moriwaki, Kiichiro Tomoda, Michio Asahi. Overexpression of Na+/H+ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK. The Journal of biological chemistry. 2019. 294. 51. 19577-19588
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MISC (5件):
  • Kenjiro Turuoka, Shigeo Wakabayashi, Ninso Matsunaga, Hirofumi Morihara, Masaaki Ii, Yasuhito Fujisaka, Isao Goto, Michio Asahi. Effect of PD-1 antibody on a mouse model for experimental autoimmune myocarditis. 18th World Congress of Basic and Clinical Pharmacology(Kyoto : 2018). 2018. WCP2018. PO4-2-20
  • Wuping Sun, Kunitoshi Uchida, Yoshiro Suzuki, Minji Kim, Nobuyuki Takahashi, Tsuyoshi Goto, Shigeo Wakabayashi, Teruo Kawada, Yuko Iwata, Makoto Tominaga. Absence of TRPV2 impaired BAT thermogenesis in mice. CHEMICAL SENSES. 2016. 41. 9. E218-E219
  • Tomoe Y. Nakamura-Nishitani, Shu Nakao, Shigeo Wakabayashi. Cardioprotective Roles of Neuronal Ca2+ Sensor-1 during Stress. BIOPHYSICAL JOURNAL. 2015. 108. 2. 609A-609A
  • Yuko Iwata, Yuki Katanosaka, Shigeo Wakabayashi. Na+/H+ exchange inhibitors protect against muscle degeneration in cardiomyopathic hamsters. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2006. 40. 6. 952-952
  • Yuki Katanosaka, Yuko Iwata, Shigeo Wakabayashi, Munekazu Shigekawa. The phosphorylation and inhibition of Na+/Ca2+ exchanger in phenylephrin-treated hypertrophic cardiomyocytes. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2006. 40. 6. 951-951
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