川口哲

カワグチサトシ | KAWAGUCHI SATOSHI

所属機関・部署：
職名：助教

研究分野 (2件)：救急医学 , 循環器内科学

研究キーワード (7件)： MicrioRNA , Long noncoding RNA , βアドレナリン受容体 , 救急医学 , 虚血性心疾患 , 敗血症 , 心不全

競争的資金等の研究課題 (4件)：

論文 (10件)：

Satoshi Kawaguchi, Bruno Moukette, Marisa N Sepúlveda, Taiki Hayasaka, Tatsuya Aonuma, Angela K Haskell, Jessica Mah, Suthat Liangpunsakul, Yaoliang Tang, Simon J Conway, et al. SPRR1A is a key downstream effector of MiR-150 during both maladaptive cardiac remodeling in mice and human cardiac fibroblast activation. Cell death & disease. 2023. 14. 7. 446-446
Satoshi Kawaguchi, Bruno Moukette, Taiki Hayasaka, Angela K Haskell, Jessica Mah, Marisa N Sepúlveda, Yaoliang Tang, Il-Man Kim. Noncoding RNAs as Key Regulators for Cardiac Development and Cardiovascular Diseases. Journal of cardiovascular development and disease. 2023. 10. 4
Bruno Moukette, Satoshi Kawaguchi, Marisa N Sepulveda, Taiki Hayasaka, Tatsuya Aonuma, Suthat Liangpunsakul, Lei Yang, Rohan Dharmakumar, Simon J Conway, Il-Man Kim. MiR-150 blunts cardiac dysfunction in mice with cardiomyocyte loss of β1-adrenergic receptor/β-arrestin signaling and controls a unique transcriptome. Cell death discovery. 2022. 8. 1. 504-504
Tatsuya Aonuma, Bruno Moukette, Satoshi Kawaguchi, Nipuni P Barupala, Marisa N Sepúlveda, Kyle Frick, Yaoliang Tang, Maya Guglin, Subha V Raman, Chenleng Cai, et al. MiR-150 Attenuates Maladaptive Cardiac Remodeling Mediated by Long Noncoding RNA MIAT and Directly Represses Profibrotic Hoxa4. Circulation. Heart failure. 2022. 15. 4. e008686
Satoshi Kawaguchi, Motoi Okada. Cardiac Metabolism in Sepsis. Metabolites. 2021. 11. 12

MISC (1件)：

Motoi Okada, Satoshi Kawaguchi, Yuta Kashiwagi, Kentaro Hayashi, Satoshi Fujita, Naoyuki Hasebe. Carvedilol Improves Prognosis in Sepsis-induced Cardiomyopathy Through the Activation of "telomere-p53-pgc Signaling". CIRCULATION. 2016. 134

書籍 (2件)：

講演・口頭発表等 (8件)：

Small Proline-rich Repeat Protein 1a Is A Significant Functional Target Of Microrna-150 In Mouse Hearts And Human Cardiac Fibroblasts
(アメリカ心臓協会)
MicroRNA-125a-5p protects the heart from ischemic injury by directly repressing pro-apoptotic GTP cyclohydrolase 1 feed regulator (GCHFR) in cardiomyocytes
(アメリア生理学学会(インディアナ))
Cardiac metabolism was improved by regulation of nitric oxide synthase through β3-adrenergic receptor in endotoxin-induced failing heart
(アメリカ心臓協会)
Endotoxin-induced cardiac metabolic shift is controlled through the regulation of fatty acid oxidation by β3-adrenergic receptor
(アメリカ心臓協会)
Blockade of β3-adrenergic receptor ameliorates septic cardiomyopathy through the improvement of cardiac fatty acid oxidation
(ヨーロッパ集中治療学会)

学歴 (2件)：

経歴 (7件)：

2023/03 - 現在旭川医科大学救急医学講座学内講師(助教)
2020/09 - 2023/02 インディアナ医科大学 Department of Anatomy, Cell Biology & Physiology 博士研究員
2020/04 - 2020/09 旭川医科大学集中治療部助教
2016/11 - 2020/03 旭川医科大学救急科助教
2015/04 - 2016/10 旭川医科大学循環器内科医員

全件表示

受賞 (2件)：

2022/11 - アメリカ心臓病協会 BCVS travel grant
2022/01 - アメリカ心臓病協会 AHA postdoctoral fellowship The roles of GCHFR and its cardiomyocyte post-transcriptional inhibitor in ischemic cardiac injury

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川口 哲