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論文 (264件)
- Rie Matsushima-Nishiwaki, Yoh Honda, Haruhiko Tokuda, Osamu Kozawa. Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2024
- Gen Kuroyanagi, Tomoyuki Hioki, Rie Matsushima-Nishiwaki, Takuya Omura, Osamu Kozawa, Haruhiko Tokuda. Gallein increases prostaglandin F2α-induced osteoprotegerin and IL-6 secretion in osteoblasts. Biomedical reports. 2024. 21. 5. 147-147
- Tomoyuki Hioki, Gen Kuroyanagi, Rie Matsushima-Nishiwaki, Takuya Omura, Osamu Kozawa, Haruhiko Tokuda. Gallein but not fluorescein enhances the PGD2-stimulated synthesis of osteoprotegerin and interleukin-6 in osteoblasts: Amplification of osteoprotegerin/interleukin-6 by gallein. Prostaglandins, leukotrienes, and essential fatty acids. 2024. 203. 102639-102639
- Gen Kuroyanagi, Tomoyuki Hioki, Rie Matsushima-Nishiwaki, Osamu Kozawa, Haruhiko Tokuda. Gallein increases the fibroblast growth factor 2-elicited osteoprotegerin synthesis in osteoblasts. Biochimica et biophysica acta. General subjects. 2024. 1868. 8. 130635-130635
- Tomoyuki Hioki, Junko Tachi, Rie Matsushima-Nishiwaki, Hiroki Iida, Osamu Kozawa, Haruhiko Tokuda. Oncostatin M suppresses bone morphogenetic protein-4-induced osteoprotegerin synthesis in MC3T3-E1 osteoblast-like cells: p70 S6 kinase attenuation. Cell biochemistry and function. 2024. 42. 4. e4068
- Haruhiko Tokuda, Takamitsu Hori, Daisuke Mizutani, Tomoyuki Hioki, Kumi Kojima, Takashi Onuma, Yukiko Enomoto, Tomoaki Doi, Rie Matsushima-Nishiwaki, Shinji Ogura, et al. Inverse relationship between platelet Akt activity and hippocampal atrophy: A pilot case-control study in patients with diabetes mellitus. World journal of clinical cases. 2024. 12. 2. 302-313
- Haruhiko Tokuda, Takamitsu Hori, Takashi Onuma, Yukiko Enomoto, Tomoaki Doi, Rie Matsushima-Nishiwaki, Shinobu Yamaguchi, Kumiko Tanabe, Takuya Omura, Shinji Ogura, et al. Serotonin reuptake inhibitor suppresses the activation of human platelets by a combination of thrombopoietin and collagen through inhibition of Rac and Rho/Rho-kinase. Biomedical research (Tokyo, Japan). 2024. 45. 6. 231-241
- Tomoyuki Hioki, Junko Tachi, Kyohei Ueda, Rie Matsushima-Nishiwaki, Hiroki Iida, Osamu Kozawa, Haruhiko Tokuda. Oncostatin M enhances osteoprotegerin synthesis but reduces macrophage colony-stimulating factor synthesis in bFGF-stimulated osteoblast-like cells. Experimental and therapeutic medicine. 2024. 27. 1. 34-34
- Gen Kuroyanagi, Tomoyuki Hioki, Rie Matsushima-Nishiwaki, Osamu Kozawa, Haruhiko Tokuda. HSP70 inhibitor amplifies the bFGF-induced release of IL-6 in osteoblasts. Molecular medicine reports. 2023. 28. 6
- Gen Kuroyanagi, Tomoyuki Hioki, Junko Tachi, Rie Matsushima-Nishiwaki, Hiroki Iida, Haruhiko Tokuda, Osamu Kozawa. Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts. Bioscience, biotechnology, and biochemistry. 2023. 87. 12. 1462-1469
- Rie Matsushima-Nishiwaki, Shota Kamoi, Osamu Kozawa. Upregulation by duloxetine of the transforming growth factor-α-induced migration of hepatocellular carcinoma cells via enhancement of the c-Jun N-terminal kinase activity. Cell biochemistry and function. 2023. 41. 7. 814-822
- Yukiko Enomoto, Takashi Onuma, Takamitsu Hori, Kumiko Tanabe, Kyohei Ueda, Daisuke Mizutani, Tomoaki Doi, Rie Matsushima-Nishiwaki, Shinji Ogura, Hiroki Iida, et al. Synergy by Ristocetin and CXCL12 in Human Platelet Activation: Divergent Regulation by Rho/Rho-Kinase and Rac. International journal of molecular sciences. 2023. 24. 11
- Gen Kuroyanagi, Tomoyuki Hioki, Junko Tachi, Rie Matsushima-Nishiwaki, Hiroki Iida, Osamu Kozawa, Haruhiko Tokuda. Oncostatin M stimulates prostaglandin D2-induced osteoprotegerin and interleukin-6 synthesis in osteoblasts. Prostaglandins, leukotrienes, and essential fatty acids. 2023. 192. 102575-102575
- 黒柳 元, 日置 智之, 西脇 理英, 徳田 治彦, 小澤 修, 村上 英樹. オンコスタチンMは骨芽細胞においてAktの活性化を阻害しTNF-αによるマクロファージコロニー刺激因子の産生を抑制する. 日本整形外科学会雑誌. 2023. 97. 3. S822-S822
- Hiroki Iida, Takashi Onuma, Daiki Nakashima, Daisuke Mizutani, Takamitsu Hori, Kyohei Ueda, Tomoyuki Hioki, Woo Kim, Yukiko Enomoto, Tomoaki Doi, et al. Tramadol regulates the activation of human platelets via Rac but not Rho/Rho-kinase. PloS one. 2023. 18. 1. e0279011
- Tomoyuki Hioki, Gen Kuroyanagi, Rie Matsushima-Nishiwaki, Osamu Kozawa, Haruhiko Tokuda. Oncostatin M attenuates tumor necrosis factor-α-induced synthesis of macrophage-colony stimulating factor via suppression of Akt in osteoblasts. Connective Tissue Research. 2023. 64. 2. 139-147
- Rie Matsushima-Nishiwaki, Hidenori Toyoda, Atsuyuki Maeda, Yuji Kaneoka, Takashi Kumada, Osamu Kozawa. Correlation between the complex of small heat shock proteins (HSPBs) and the progression in patients with hepatocellular carcinoma. Archives of Biochemistry and Biophysics. 2022. 732
- Gen Kuroyanagi, Junko Tachi, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Daiki Nakashima, Woo Kim, Kumiko Tanabe, Rie Matsushima-Nishiwaki, Takanobu Otsuka, et al. HSP70 inhibitors upregulate prostaglandin E1-induced synthesis of interleukin-6 in osteoblasts. PLoS ONE. 2022. 17. 12 December. e0279134-e0279134
- Gen Kuroyanagi, Haruhiko Tokuda, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Woo Kim, Tomoyuki Hioki, Junko Tachi, Rie Matsushima-Nishiwaki, Takanobu Otsuka, et al. Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts. BMC Musculoskeletal Disorders. 2022. 23. 1. 495-495
- Daisuke Mizutani, Haruhiko Tokuda, Takashi Onuma, Kodai Uematsu, Daiki Nakashima, Kyohei Ueda, Tomoaki Doi, Yukiko Enomoto, Rie Matsushima-Nishiwaki, Shinji Ogura, et al. Amyloid β protein negatively regulates human platelet activation induced by thrombin receptor-activating protein. Bioscience, Biotechnology and Biochemistry. 2022. 86. 2. 185-198
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