研究者
J-GLOBAL ID:201901020474275635
更新日: 2025年01月14日 キム ヒョンジン
HyunJin Kim
- Debabrata Maiti, Hao Yu, Jun Su An, Shinichi Yamashita, Mitsuru Naito, Kanjiro Miyata, Hyun Jin Kim. Dual Porphyrin-Loaded Scintillating Nanoparticles Enhanced Photodynamic Therapy in Hypoxic Cancer Cells under X-ray Irradiation. Chembiochem : a European journal of chemical biology. 2024. e202400838
- Jongmin Yum, Fadlina Aulia, Keisuke Kamiya, Mao Hori, Nan Qiao, Beob Soo Kim, Mitsuru Naito, Satomi Ogura, Tetsuya Nagata, Takanori Yokota, et al. Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery. Bioconjugate chemistry. 2024
- Mohit J Mehta, Hyun Jin Kim, Sung Been Lim, Mitsuru Naito, Kanjiro Miyata. Recent Progress in the Endosomal Escape Mechanism and Chemical Structures of Polycations for Nucleic Acid Delivery. Macromolecular bioscience. 2024. e2300366
- Debabrata Maiti, Hao Yu, Yuki Mochida, Seongyeon Won, Shinichi Yamashita, Mitsuru Naito, Kanjiro Miyata, Hyun Jin Kim. Terbium-Rose Bengal Coordination Nanocrystals-Induced ROS Production under Low-Dose X-rays in Cultured Cancer Cells for Photodynamic Therapy. ACS Applied Bio Materials. 2023. 6. 6. 2505-2513
- Debabrata Maiti, Hao Yu, Beob Soo Kim, Mitsuru Naito, Shinichi Yamashita, Hyun Jin Kim, Kanjiro Miyata. Rose Bengal Decorated NaYF4:Tb Nanoparticles for Low Dose X-ray-Induced Photodynamic Therapy in Cancer Cells. ACS applied bio materials. 2022. 5. 11. 5477-5486
- Hyun Jin Kim, Ahram Kim, Kanjiro Miyata. Synthetic molecule libraries for nucleic acid delivery: Design parameters in cationic/ionizable lipids and polymers. Drug metabolism and pharmacokinetics. 2022. 42. 100428-100428
- Jongmin Yum, Beob Soo Kim, Satomi Ogura, Rimpei Kamegawa, Mitsuru Naito, Yuichi Yamasaki, Hyun Jin Kim, Kanjiro Miyata. Fine-tuning of polyaspartamide derivatives with alicyclic moieties for systemic mRNA delivery. Journal of controlled release : official journal of the Controlled Release Society. 2022. 342. 148-156
- Rimpei Kamegawa, Mitsuru Naito, Satoshi Uchida, Hyun Jin Kim, Beob Soo Kim, Kanjiro Miyata. Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery. ACS applied bio materials. 2021. 4. 11. 7790-7799
- Beob Soo Kim, Mitsuru Naito, Hiroyuki Chaya, Mao Hori, Kotaro Hayashi, Hyun Su Min, Yu Yi, Hyun Jin Kim, Tetsuya Nagata, Yasutaka Anraku, et al. Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown. Biomacromolecules. 2020. 21. 10. 4365-4376
- Hyun Su Min, Hyun Jin Kim, Mitsuru Naito, Satomi Ogura, Kazuko Toh, Kotaro Hayashi, Beob Soo Kim, Shigeto Fukushima, Yasutaka Anraku, Kanjiro Miyata, et al. Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier. Angewandte Chemie (International ed. in English). 2020. 59. 21. 8173-8180
- Beob Soo Kim, Mitsuru Naito, Rimpei Kamegawa, Hyun Jin Kim, Ryo Iizuka, Takashi Funatsu, Shingo Ueno, Takanori Ichiki, Akihiro Kishimura, Kanjiro Miyata. Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown. Chemical Communications. 2020. 56. 66. 9477-9480
- H. S. Min*, H. J. Kim*, M. Naito, S. Ogura, K. Toh, K. Hayashi, B. S. Kim, S. Fukushima, Y. Anraku, K. Miyata, K. Kataoka. Systemic Brain Delivery of Antisense Oligonucleotides across the Brain-Brain Barrier with a Glucose-Installed Polymeric Nanocarrier. Angew. Chem. Int. Ed. 2020
- Hyun Jin Kim, Satomi Ogura, Takahiro Otabe, Rimpei Kamegawa, Moritoshi Sato, Kazunori Kataoka, Kanjiro Miyata. Fine-Tuning of Hydrophobicity in Amphiphilic Polyaspartamide Derivatives for Rapid and Transient Expression of Messenger RNA Directed Toward Genome Engineering in Brain. ACS Central Science. 2019. 5. 11. 1866-1875
- Beob Soo Kim, Hyun Jin Kim, Shigehito Osawa, Kotaro Hayashi, Kazuko Toh, Mitsuru Naito, Hyun Su Min, Yu Yi, Ick Chan Kwon, Kazunori Kataoka, et al. Dually Stabilized Triblock Copolymer Micelles with Hydrophilic Shell and Hydrophobic Interlayer for Systemic Antisense Oligonucleotide Delivery to Solid Tumor. ACS Biomaterials Science & Engineering. 2019. 5. 11. 5770-5780
- A 50-nm-sized micellar assembly of thermoresponsive polymer-antisense oligonucleotide conjugates for enhanced gene knockdown in lung cancer by intratracheal administration. Advanced Therapeutics. 2019. 1900123
- S. Watanabe*, K. Hayashi*, K. Toh*, H. J. Kim*, X. Liu, H. Chaya, S. Fukushima, K. Katsushima, Y. Kondo, S. Uchida, S. Ogura, T. Nomoto, H. Takemoto, H. Cabral, H. Kinoh, H. Y. Tanaka, M. R. Kano, Y. Matsumoto, H. Fukuhara, S. Uchida, M. Nangaku, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka. In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers. Nature Communications. 2019. 10. 1894
- Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells. Journal of Controlled Release. 2019. 295. 268-277
- Tunable non-enzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency. Science and Technology of Advanced Materials. 2019. 20. 1. 105-115
- Self-assembly of siRNA/PEG-b-catiomer at integer molar ratio into 100 nm-sized vesicular polyion complexes (siRNAsomes) for RNAi and codelivery of cargo macromolecules. Journal of the American Chemical Society. 2019. 141. 8. 3699-3709
- H. J. Kim, Y. Yi, A. Kim, K. Miyata. Small delivery vehicles of siRNA for enhanced cancer targeting. Biomacromolecules. 2018. 19. 2377-2390
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