文献

J-GLOBAL ID：201902286045412205   整理番号：19A0715477

頚椎後縦靭帯の重度骨化症患者における骨化脊髄病変の分布と頸部OP指数分類に基づく各区域における骨化の予測:多施設共同研究(JOSL CT研究)【JST・京大機械翻訳】

Distribution of ossified spinal lesions in patients with severe ossification of the posterior longitudinal ligament and prediction of ossification at each segment based on the cervical OP index classification: a multicenter study (JOSL CT study)

著者 (69件)： Hirai Takashi (Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan) ,  Hirai Takashi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Yoshii Toshitaka (Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan) ,  Yoshii Toshitaka (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Nagoshi Narihito (Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan) ,  Takeuchi Kazuhiro (Department of Orthopedic Surgery, National Hospital Organization Okayama Medical Center, Okayama, Japan) ,  Takeuchi Kazuhiro (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Mori Kanji (Department of Orthopedic Surgery, Shiga University of Medical Science, Otsu, Japan) ,  Mori Kanji (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Ushio Shuta (Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan) ,  Ushio Shuta (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Iwanami Akio (Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan) ,  Yamada Tsuyoshi (Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan) ,  Yamada Tsuyoshi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Seki Shoji (Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan) ,  Seki Shoji (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Tsuji Takashi (Department of Orthopedic Surgery, Fujita Health University, Toyoake, Japan) ,  Tsuji Takashi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Fujiyoshi Kanehiro (Department of Orthopedic Surgery, National Hospital Organization Murayama Medical Center, Tokyo, Japan) ,  Fujiyoshi Kanehiro (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Furukawa Mitsuru (Department of Orthopedic Surgery, Shizuoka City Shimizu Hospital, Shizuoka, Japan) ,  Furukawa Mitsuru (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Nishimura Soraya (Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan) ,  Nishimura Soraya (Department of Orthopedic Surgery, Keiyu Hospital, Yokohama, Japan) ,  Nishimura Soraya (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Wada Kanichiro (Department of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Wada Kanichiro (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Furuya Takeo (Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan) ,  Furuya Takeo (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Matsuyama Yukihiro (Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan) ,  Matsuyama Yukihiro (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Hasegawa Tomohiko (Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan) ,  Hasegawa Tomohiko (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Takeshita Katsushi (Department of Orthopedics, Jichi Medical University, Shimotsuke, Japan) ,  Takeshita Katsushi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Kimura Atsushi (Department of Orthopedics, Jichi Medical University, Shimotsuke, Japan) ,  Kimura Atsushi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Abematsu Masahiko (Department of Orthopedic Surgery, Graduate School of Medicine and Dental Science, Kagoshima University, Kagoshima, Japan) ,  Abematsu Masahiko (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Haro Hirotaka (Department of Orthopedic Surgery, University of Yamanashi, Yamanashi, Japan) ,  Haro Hirotaka (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Ohba Tetsuro (Department of Orthopedic Surgery, University of Yamanashi, Yamanashi, Japan) ,  Ohba Tetsuro (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Watanabe Masahiko (Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara, Japan) ,  Watanabe Masahiko (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Katoh Hiroyuki (Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara, Japan) ,  Katoh Hiroyuki (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Watanabe Kei (Department of Orthopedic Surgery, Niigata University Medicine and Dental General Hospital, Niigata, Japan) ,  Watanabe Kei (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Ozawa Hiroshi (Department of Orthopedic Surgery, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Ozawa Hiroshi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Kanno Haruo (Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan) ,  Kanno Haruo (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Imagama Shiro (Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Imagama Shiro (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Ando Kei (Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Ando Kei (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Fujibayashi Shunsuke (Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Fujibayashi Shunsuke (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Koda Masao (Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan) ,  Koda Masao (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Yamazaki Masashi (Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan) ,  Yamazaki Masashi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Matsumoto Morio (Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan) ,  Nakamura Masaya (Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan) ,  Okawa Atsushi (Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan) ,  Okawa Atsushi (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan) ,  Kawaguchi Yoshiharu (Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan) ,  Kawaguchi Yoshiharu (Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), Tokyo, Japan)
資料名： BMC Musculoskeletal Disorders (Web)  (BMC Musculoskeletal Disorders (Web))
巻： 19  号： 1  ページ： 107  発行年： 2018年 
JST資料番号： U7436A  ISSN： 1471-2474  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： イギリス (GBR)  言語： 英語 (EN)

抄録/ポイント： 頚椎における後縦靭帯骨化症(OPLL)患者において,胸部骨化病変はしばしば頚部病変と共存し,重篤な脊髄障害を引き起こすことがよく知られている。しかし,胸部および腰部脊髄分節の各レベルにおけるOPLLの罹患率は不明である。本研究の目的は,頸部OPLLの放射線学的診断を有する患者における胸腰椎の各レベルでしばしばOPLLが発生し,骨化を発症する可能性が最も高い脊髄レベルを同定することである。日本の20施設からデータを収集した。頚部OPLLと診断された患者132名を対象とした。OPLLが存在する椎体と椎間板レベルの合計として定義されるOPLL指数(OP指数)は,疾患重症度を決定するために使用された。OP指数≧20を重症OPLLと定義した。胸部および腰部脊髄分節の各レベルにおけるOPLLの罹患率を計算した。女性は,男性より胸腰椎において骨化病変を有する可能性が高かった。重度OPLLは男性より女性で有意に多かった(20%対4.5%)。胸椎OPLLに対して,最も頻繁に影響されたのは,男性と女性の両方でT1セグメントであり,男性と女性ではそれぞれT1/2とT3/4の椎間レベルが続いた。骨化病変は,重度OPLLを有する男性において,頚胸および胸腰椎接合部周辺の椎間および脊椎レベルで頻繁に見られたが,OPLLは,重度OPLLを有する女性において胸椎においてより拡散的に分布していた。胸腰椎OPLLは男性ではT1,女性ではT3/4で最も多かった。重篤なOPLL症例では,骨化病変は,男性において頚胸および胸腰椎接合部周辺の椎間および脊椎レベルで頻繁に見られたが,OPLLは女性において胸椎においてより拡散的に観察された。Copyright 2019 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 接合部 ,  *予測 ,  *脊髄 ,  計算機トモグラフィー ,  放射線医学 ,  男性 ,  胸椎 ,  椎間板 ,  *骨形成 ,  *頚椎 ,  女性 ,  罹患率
準シソーラス用語： 重症度 ,  胸腰椎 ,  *病巣 , 【Automatic Indexing@JST】

著者キーワード (5件)： OPLL ,  コンピュータ断層撮影 ,  全脊椎 ,  骨化素因 ,  有病率

分類 (2件)： 運動器系の疾患  (GG03000T) ,  運動器系疾患の外科療法  (GG05030O)

引用文献 (19件)：

• Spine; Five-year follow-up evaluation of surgical treatment for cervical myelopathy caused by ossification of the posterior longitudinal ligament: a prospective comparative study of anterior decompression and fusion with floating method versus laminoplasty; K Sakai, A Okawa, M Takahashi, Y Arai, S Kawabata, M Enomoto, T Kato, T Hirai, K Shinomiya; 37; 5; 2012; 367-376; 10.1097/BRS.0b013e31821f4a51; citation_id=CR1
• J Neurosurg Spine; Outcomes of fusion surgery for ossification of the posterior longitudinal ligament of the thoracic spine: a multicenter retrospective survey: clinical article; M Matsumoto, Y Toyama, H Chikuda, K Takeshita, T Kato, S Shindo, K Abumi, M Takahata, Y Nohara, H Taneichi, K Tomita, N Kawahara, S Imagama, Y Matsuyama, M Yamazaki, A Okawa; 15; 4; 2011; 380-385; 10.3171/2011.6.SPINE10816; citation_id=CR2
• Guy Hosp Rep; On paraplegia depending on the ligament of the spine; GA Key; 3; 1838; 17-34; citation_id=CR3
• Spine; Prevalence, distribution, and morphology of thoracic ossification of the posterior longitudinal ligament in Japanese: results of CT-based cross-sectional study; K Mori, S Imai, T Kasahara, K Nishizawa, T Mimura, Y Matsusue; 39; 5; 2014; 394-399; 10.1097/BRS.0000000000000153; citation_id=CR4
• Spine; Ossification of the posterior longitudinal ligament in not only the cervical spine, but also other spinal regions: analysis using multidetector computed tomography of the whole spine; Y Kawaguchi, M Nakano, T Yasuda, S Seki, T Hori, T Kimura; 38; 23; 2013; E1477-E1482; 10.1097/BRS.0b013e3182a54f00; citation_id=CR5

タイトルに関連する用語 (15件)： 頚椎 ,  縦靭帯 ,  骨化症 ,  患者 ,  骨化 ,  脊髄病変 ,  分布 ,  頸部 ,  指数 ,  分類 ,  区域 ,  予測 ,  多施設共同研究 ,  CT ,  研究