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論文 (26件)
- Takuma Matsushita, Shinji Kishimoto, Kodai Hara, Hiroshi Hashimoto, Hideki Yamaguchi, Yutaka Saito, Kenji Watanabe. Functional Enhancement of Flavin-Containing Monooxygenase through Machine Learning Methodology. ACS Catalysis. 2024. 14. 9. 6945-6951
- Shinji Kishimoto, Ayumi Minami, Yoshimitsu Aoki, Yuya Matsubara, Shogo Watanabe, Kenji Watanabe. Reactive Azlactone Intermediate Drives Fungal Secondary Metabolite Cross-Pathway Generation. Journal of the American Chemical Society. 2023. 145. 5. 3221-3228
- Takuma Kobayashi, Shinji Kishimoto, Shogo Watanabe, Yasukiyo Yoshioka, Takeshi Toyoda, Kumiko Ogawa, Kenji Watanabe, Yukari Totsuka, Keiji Wakabayashi, Noriyuki Miyoshi. Cytotoxic Homo- and Hetero-Dimers of o-toluidine, o-anisidine, and Aniline Formed by In Vitro Metabolism. Chemical research in toxicology. 2022. 35. 9. 1625-1630
- Takumi Okamoto, Shinji Kishimoto, Kenji Watanabe. Isolation of Natural Prodrug-Like Metabolite by Simulating Human Prodrug Activation in Filamentous Fungus. Chemical and Pharmaceutical Bulletin. 2022. 70. 4. 304-308
- Shinji Kishimoto, Yuya Matsubara, Kenji Watanabe. Alkaloid Biosynthetic Enzyme Generates Diastereomeric Pair via Two Distinct Mechanisms. Journal of the American Chemical Society. 2022. 144. 12. 5485-5493
- Shinya Matsuda, Yuta Tsunematsu, Takuma Matsushita, Yuji Ogata, Shihomi Hachiya, Shinji Kishimoto, Noriyuki Miyoshi, Kenji Watanabe. Toward Engineered Biosynthesis of Drugs in Human Cells. ChemBioChem. 2022. 23. 4
- Hamoya, T., Fujii, G., Iizumi, Y., Narita, T., Komiya, M., Matsuzawa, Y., Miki, K., Kondo, T., Kishimoto, S., Watanabe, K., et al. Artesunate inhibits intestinal tumorigenesis through inhibiting wnt signaling. Carcinogenesis. 2021. 42. 1. 148-158
- Kobayashi, T., Toyoda, T., Tajima, Y., Kishimoto, S., Tsunematsu, Y., Sato, M., Matsushita, K., Yamada, T., Shimamura, Y., Masuda, S., et al. O-Anisidine Dimer, 2-Methoxy- N4-(2-methoxyphenyl) Benzene-1,4-diamine, in Rat Urine Associated with Urinary bladder Carcinogenesis. Chemical Research in Toxicology. 2021. 34. 3. 912-919
- Sato, M., Kishimoto, S., Yokoyama, M., Jamieson, C.S., Narita, K., Maeda, N., Hara, K., Hashimoto, H., Tsunematsu, Y., Houk, K.N., et al. Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase. Nature Catalysis. 2021. 4. 3. 223-+
- Matsushita, T., Kishimoto, S., Hara, K., Hashimoto, H., Watanabe, K. Structural and Functional Analyses of a Spiro-Carbon-Forming, Highly Promiscuous Epoxidase from Fungal Natural Product Biosynthesis. Biochemistry. 2020. 59. 51. 4787-4792
- Kishimoto, S., Tsunematsu, Y., Matsushita, T., Hara, K., Hashimoto, H., Tang, Y., Watanabe, K. Functional and Structural Analyses of trans C-Methyltransferase in Fungal Polyketide Biosynthesis. Biochemistry. 2019. 58. 38
- Shinji Kishimoto, Kodai Hara, Hiroshi Hashimoto, Yuichiro Hirayama, Pier Alexandre Champagne, Kendall N. Houk, Yi Tang, Kenji Watanabe. Enzymatic one-step ring contraction for quinolone biosynthesis. Nature Communications. 2018. 9. 1. 2826-2826
- Shinji Kishimoto, Yuta Tsunematsu, Michio Sato, Kenji Watanabe. Elucidation of Biosynthetic Pathways of Natural Products. The Chemical Record. 2017. 17. 11. 1095-1108
- Mamoru Yokoyama, Yuichiro Hirayama, Tsuyoshi Yamamoto, Shinji Kishimoto, Yuta Tsunematsu, Kenji Watanabe. Integration of Chemical, Genetic, and Bioinformatic Approaches Delineates Fungal Polyketide-Peptide Hybrid Biosynthesis. Organic Letters. 2017. 19. 8. 2002-2005
- Shinji Kishimoto, Michio Sato, Yuta Tsunematsu, Kenji Watanabe. Evaluation of Biosynthetic Pathway and Engineered Biosynthesis of Alkaloids. Molecules. 2016. 21. 8. 1078-1078
- Hiroki Kato, Yuta Tsunematsu, Tsuyoshi Yamamoto, Takuya Namiki, Shinji Kishimoto, Hiroshi Noguchi, Kenji Watanabe. New natural products isolated from Metarhizium robertsii ARSEF 23 by chemical screening and identification of the gene cluster through engineered biosynthesis in Aspergillus nidulans A1145. The Journal of Antibiotics. 2016. 69. 7. 561-566
- Michio Sato, Jaclyn M. Winter, Shinji Kishimoto, Hiroshi Noguchi, Yi Tang, Kenji Watanabe. Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis. Organic Letters. 2016. 18. 6. 1446-1449
- Shinji Kishimoto, Shinichi Nishimura, Hideaki Kakeya. ChemInform Abstract: Total Synthesis and Structure Revision of Mirubactin, and Its Iron Binding Activity. ChemInform. 2016. 47. 16
- Yamamoto, T., Tsunematsu, Y., Hara, K., Suzuki, T., Kishimoto, S., Kawagishi, H., Noguchi, H., Hashimoto, H., Tang, Y., Hotta, K., et al. Oxidative trans to cis isomerization of olefins in polyketide biosynthesis. Angewandte Chemie - International Edition. 2016. 55. 21. 6315-6318
- Shinji Kishimoto, Shinichi Nishimura, Masaki Hatano, Masayuki Igarashi, Hideaki Kakeya. Total Synthesis and Antimicrobial Activity of Chlorocatechelin A. The Journal of Organic Chemistry. 2015. 80. 12. 6076-6082
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