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Rchr
J-GLOBAL ID：200901004140384961
Update date: Aug. 30, 2020 Ogura Kenichiro
オグラ ケンイチロウ | Ogura Kenichiro
Clips
Tokyo University of Pharmacy and Life Science School of Pharmacy, Department of Drug Metabolism and Molecular Toxicology
About Tokyo University of Pharmacy and Life Science School of Pharmacy, Department of Drug Metabolism and Molecular Toxicology
Job title： Associate Professor
Research keywords (7)：
Dihyropyrimidine dehydrogenase
, UDP-Glucuronosyltransferase
, SUlfotransferase
, Drug Metabolizing Enzymes
, Drug Metabolism
, 薬物代謝・分子毒性学
, Drug Metabolism and Molecular Toxicology
Research theme for competitive and other funds (5)： - 2012 - 2014 乳がん細胞の抗がん剤耐性化に関与する薬物代謝酵素の役割
- 2005 - 2007 乳がん治療薬タモキシフェン耐性腫瘍の耐性機構の解明
- 2002 - 2004 植物エストロゲンの硫酸ならびにグルクロン酸抱合反応による代謝
- 薬物代謝酵素の構造と機能に関する研究
- Study on Structure and Function of Drug Metabolizing Enzymes
- Tomokazu Ohnuma, Kazuya Sakamoto, Asumi Shinoda, Chiaki Takagi, Shoko Ohno, Takahito Nishiyama, Kenichiro Ogura, Akira Hiratsuka. Procyanidins from Cinnamomi Cortex promote proteasome-independent degradation of nuclear Nrf2 through phosphorylation of insulin-like growth factor-1 receptor in A549 cells. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2017. 635. 66-73
- Tomokazu Ohnuma, Eri Anzai, Yohei Suzuki, Mai Shimoda, Shin Saito, Takahito Nishiyama, Kenichiro Ogura, Akira Hiratsuka. Selective antagonization of activated Nrf2 and inhibition of cancer cell proliferation by procyanidins from Cinnamomi Cortex extract. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2015. 585. 17-24
- Yoichiro Yoshida, Kenichiro Ogura, Akira Hiratsuka, Naoya Aisu, Teppei Yamada, Daibo Kojima, Syu Tanimura, Kentaro Ogata, Shuuji Hara, Ai Mogi, et al. 5-Fluorouracil Chemotherapy for Dihydropyrimidine Dehydrogenase-deficient Patients: Potential of the Dose-escalation Method. ANTICANCER RESEARCH. 2015. 35. 9. 4881-4887
- Kenichiro Ogura, Yuji Ishii. Significance of non-cytochrome P450 (non-P450) enzymes in basic science, clinical field and drug development Preface. DRUG METABOLISM AND PHARMACOKINETICS. 2015. 30. 1. 1-2
- Takahito Nishiyama, Nahoko Hayashi, Naoki Kakurai, Hiromi Yanagita, Ai Kuriyama, Chika Miyamoto, Yumi Ishihara, Kenichiro Ogura, Tomokazu Ohnuma, Akira Hiratsuka. Formation and stability of 4-(hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronide, a stable form of reactive intermediate produced from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, in mice. JOURNAL OF TOXICOLOGICAL SCIENCES. 2014. 39. 4. 515-521
- 1984 - 1986 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
- - 1986 Tokyo University of Pharmacy and Life Science Graduate School, Division of Pharmaceutical Sciences
- 1983 - 1984 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
- 1979 - 1983 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy
- - 1983 Tokyo University of Pharmacy and Life Science Faculty of Pharmaceutical Science
- (BLANK)
- Ph.D. (Tokyo University of Pharmacy and Life Science)
- 2007/04 - 現在 Tokyo University of Pharmacy and Life Sciences
- 2004/04 - 2007/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
- 1999 - 2004 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
- 1986 - 1998 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
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