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J-GLOBAL ID：200901006807445967 Update date: Apr. 10, 2025

Tsunahiko Hirano

ヒラノツナヒコ | Tsunahiko Hirano

Affiliation and department：
Homepage URL (1)： http://www.kokyuki.med.yamaguchi-u.ac.jp

Research field (2)： Allergies and connective tissue disease , Respiratory medicine

Research keywords (9)：窒素化ストレス , TNF-LIGHT , HPLC , 難治性喘息 , テオフィリン , 3-ニトロタイロシン , ニトロタイロシン , 呼気NO , 慢性閉塞性肺疾患

Research theme for competitive and other funds (16)：

2024 - 2027 COPD身体活動性の長期維持に向けた具体的方策の探求
2023 - 2026 Elucidation of the pathophysiology of activity limitation in patients with severe asthma and establishment of a diagnostic and therapeutic support system
2023 - 2026 Influence of reduced physical activity on the pathophysiology of asthma
2023 - 2026 Early detection of frailty and development of the pathophysiology management system in COPD
2024 - 2026 生体音センサを用いた呼吸器疾患の革新的検査システム

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Papers (183)：

Yuka Fujioka, Yukinori Nakamura, Kaoru Yamamoto, Yoshihiro Tokunaga, Shota Nono, Takahiro Sasaki, Kohei Sakai, Kohei Okamura, Taishi Ando, Hiroko Nakabayashi, et al. Bronchial structural changes analyzed with three-dimensional computed tomography correlate with severe acute graft-versus-host disease after allogenic hematopoietic stem cell transplantation. Annals of hematology. 2025
Keiji Oishi, Kazuki Hamada, Ayumi Fukatsu-Chikumoto, Yoriyuki Murata, Maki Asami-Noyama, Nobutaka Edakuni, Tsunahiko Hirano, Kazuto Matsunaga. Clinical Remission in Patients With Biologic-Naïve Asthma: A Multicenter Study in Japan. The journal of allergy and clinical immunology. In practice. 2024
Naoya Tanabe, Yu Hara, Kaoruko Shimizu, Satoshi Marumo, Jun Miyata, Kyohei Morita, Tetsuya Watanabe, Keiji Oishi, Masafumi Yamaguchi, Kazuhisa Asai, et al. A protocol for a Japanese prospective cohort evaluating the features of patients with uncontrolled asthma achieving clinical remission: J-CIRCLE. Respiratory investigation. 2024. 62. 6. 1209-1214
Yunjin Zhang, Minoru Morita, Tsunahiko Hirano, Keiko Doi, XIN HAN, Kazuto Matsunaga, Zhongwei Jiang. A Novel Method for Identifying Frailty and Quantifying Muscle Strength Using the Six-Minute Walking Test. Sensors. 2024. 24. 14. 4489-4489
Tomoyuki Kakugawa, Yusuke Mimura, Yuka Mimura-Kimura, Keiko Doi, Yuichi Ohteru, Hiroyuki Kakugawa, Keiji Oishi, Masahiro Kakugawa, Tsunahiko Hirano, Kazuto Matsunaga. Kinetics of pro- and anti-inflammatory spike-specific cellular immune responses in long-term care facility residents after COVID-19 mRNA primary and booster vaccination: a prospective longitudinal study in Japan. Immunity & Ageing. 2024. 21. 1. 41-41

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MISC (329)：

栗原有紀, 高橋浩一郎, 田代宏樹, 浅井一久, 佐々木誠悟, 中西正典, 平野綱彦, 松永和人, 南方良章. COPD患者において座位時間と歩数の変化量は相関しない. 日本呼吸ケア・リハビリテーション学会誌. 2024. 34. Suppl. 148s-148s
大石景士, 濱田和希, 深津愛祐美, 浅見麻紀, 枝國信貴, 平野綱彦, 松永和人. 気管支喘息(成人):臨床的寛解1 喘息患者の臨床的寛解達成率の検討. アレルギー. 2024. 73. 6-7. 834-834
深津愛祐美, 平野綱彦, 岩本博志, 土居恵子, 村田順之, 檜垣直子, 天野芳宏, 山根真由香, 横山彰仁, 礒部威, et al. 気管支喘息(成人):診断・評価3 喘息の身体活動の多様性と胸部医療画像の意義. アレルギー. 2024. 73. 6-7. 841-841
川本数真, 岩本博志, 檜垣直子, 村川慶多, 深津愛祐美, 大谷俊人, 山根真由香, 天野芳宏, 山路義和, 平野綱彦, et al. 気管支喘息(成人):診断・評価3 喘息患者における身体活動性と心理的因子の関連性に関する検討. アレルギー. 2024. 73. 6-7. 842-842
近藤芽生, 間普真吾, 平野綱彦, 村田順之, 土居恵子, 深津愛祐美, 楊鯤昊, 松永和人. 吸気・呼気CT画像を用いた慢性閉塞性肺疾患における身体活動性予測. 日本医用画像工学会大会予稿集. 2024. 43回. 51-51

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Patents (2)：

Books (1)：

【喘息.COPD.喘息・COPDオーバーラップ症候群の病態生理】治療薬解説 ICS,LAMA,LABAの特性と使い分け
(株)ライフメディコム 2023 ISBN:9784898133576

Lectures and oral presentations (10)：

成人喘息の疫学,環境因子,フェノタイプ喘息患者の身体活動性低下に関連するリスク因子,フェノタイプの検討
(アレルギー 2023)
COPD合併を含む喘息の身体非活動を検出する基本チェックリストの有用性
(アレルギー 2023)
らっきょうを気管内に誤嚥し,気管支鏡下での摘出時に気管支結核を認めた一例
(気管支学 2023)
当院における肺MAC症の臨床的検討
(結核 2023)
COPD 病理・病態生理 COPDの海馬萎縮を検出する基本チェックリストの有用性
(日本呼吸器学会誌 2023)

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Education (1)：

- 1994 Wakayama Medical University Faculty of Medicine

Professional career (1)：

M.D.,Ph.D. (Wakayama Medical University)

Work history (2)：

2015/08 - 現在 Graduate School of Medicine,Yamaguchi University Division of Respiratory Medicine and Infectious Disease Associate Professor
2013 - Wakayama Medical University Faculty of Medicine

Awards (4)：

2020/11 - Asian Pacific Society of Respirology Asthma Assembly Symposium silver award Airway TNF-LIGHT expression and associated molecular inflammatory profiles in asthma patients with persistent airflow limitation
2017/10 - 山口大学第122回山口大学医学会学術講演会学術講演会奨励賞気道リモデリングにおけるTNFLIGHTと窒素化ストレスのクロストークの役割
2008/07 - Wakayama Medical Society Seishu Award Inhibition of reactive nitrogen species production in COPD:comparison of inhaled coricosteroid and oral theophylline
2003/11 - The japanese respiratory society Pneumo Forum Inhibition of reactive nitrogen species production in COPD airways: comparison of inhaled corticosteroid and oral theophylline.

Association Membership(s) (10)：

日本呼吸ケア・リハビリテーション学会 , アジア太平洋呼吸器学会 , Europe Respiratory Society , The American Thoracic Society , THE JAPANESE ASSOCIATION FOR INFECTIOUS DISEASES , THE JAPAN LUNG CANCER SOCIETY , THE JAPAN SOCIETY FOR RESPIRATORY ENDOSCOPY , JAPANESE SOCIETY OF ALLERGOLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , THE JAPANESE RESPIRATORY SOCIETY

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