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J-GLOBAL ID：200901052287445405   Update date: Apr. 24, 2025

Sato Takeshi

サトウ タケシ | Sato Takeshi
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Affiliation and department：
Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmacy

About Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmacy


Job title： Associate Professor
Other affiliations (1)：
Research field  (3)： Bioorganic chemistry ,  Biophysics ,  Structural biochemistry
Research keywords  (6)： Peptide Chemistry ,  Solid State NMR ,  Membrane Protein ,  Structural Biology ,  Biophysics ,  Protein Chemistry
Research theme for competitive and other funds  (7)：
  • 2021 - 2024 Mechanism of Notch receptor signaling and its dependency on lipids
  • 2016 - 2019 Chemical synthesis of caveolin
  • 2014 - 2018 Elucidation of substrate recognition mechanism of I-CLiP in the trans- and juxta-membrane regions
  • 2014 - 2015 1回膜貫通型蛋白質を一方向でリポソーム上に存在させる技術の開発
  • 2012 - 2015 受容体型チロシンキナーゼの半合成と構造機能解析
Show all
Papers (42)：
  • Rio Yamamoto, Ryosuke Segawa, Hiyori Kato, Yuya Niino, Takeshi Sato, Masahiro Hiratsuka, Noriyasu Hirasawa. Identification of amino acids in transmembrane domains of mutated cytokine receptor-like factor 2 and interleukin-7 receptor α required for constitutive signal transduction. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2024. 1866. 7. 184359-184359
  • Norihiro Namba, Takashi Ohgita, Hiroko Tamagaki-Asahina, Kazuchika Nishitsuji, Toshinori Shimanouchi, Takeshi Sato, Hiroyuki Saito. Amyloidogenic 60-71 deletion/ValThr insertion mutation of apolipoprotein A-I generates a new aggregation-prone segment that promotes nucleation through entropic effects. Scientific Reports. 2023. 13. 1. 18514-18514
  • Takeshi Sato, Akira Shinohara. Characterizing interaction between the juxtamembrane region of the single transmembrane protein and membrane using chemically synthesized peptides. STAR Protocols. 2023. 4. 3. 102454-102454
  • Ryo Maeda, Hiroko Tamagaki-Asahina, Takeshi Sato, Masataka Yanagawa, Yasushi Sako. Threonine phosphorylation regulates the molecular assembly and signaling of EGFR in cooperation with membrane lipids. Journal of Cell Science. 2022. 135. 15
  • Yuki Takechi-Haraya, Takashi Ohgita, Mana Kotani, Hiroki Kono, Chihiro Saito, Hiroko Tamagaki-Asahina, Kazuchika Nishitsuji, Kenji Uchimura, Takeshi Sato, Ryuji Kawano, et al. Effect of hydrophobic moment on membrane interaction and cell penetration of apolipoprotein E-derived arginine-rich amphipathic α-helical peptides. Sci.Rep. 2022. 23. 12. 4959
ｍore...
MISC (6)：
ｍore...
Lectures and oral presentations  (15)：
  • Chemical Synthesis of Membrane Protein
    (International Conference at National Taiwan University 2024)
  • Function of transmembrane-juxtammebrane region of EGFR
    (Symposium in the 56th annual meeting of the Biophysical Society of Japan, “Regulation of the signal transduction in cell membrane via localization and clustering of receptors” 2018)
  • Signaling across the membrane by receptor tyrosine kinase
    (International Seminar on Biophysics and Chemical Biology of Biomembrane and Lipid Bilayers 2017)
  • Synthetic peptide for structure and function of membrane protein
    (IPR International Seminar 2016)
  • Research on structure and function of membrane protein using synthetic transmembrane peptides
    (19th Korean Peptide Protein Symposium 2015)
ｍore...
Education (2)：
  • 1999 - 2004 Graduate School of Science, Osaka University
  • - 1999 Yokohama National University
Professional career (1)：
  • PhD(Science) (Osaka Univ.)
Work history (5)：
  • 2017/04 - 現在 Kyoto Pharmaceutical University
  • 2014/08 - 2017/03 Institute for Protein Research, Osaka University Associate Professor
  • 2005/04 - 2014/07 Institute for Protein Research, Osaka University Assistant Professor
  • 2004/04 - 2006/02 ニューヨーク州立ストーニーブルック大学生化学・細胞生物学研究科構造生物学センター・博士研究員
  • 2004 - 2005 Postdoctoral Research Associate at Department of Biochemistry and Cell Biology, Center for Structural Biology, Stony Brook University
Awards (2)：
  • 2013/08 - Osaka University Young Investigator`s Award
  • 2011/09 - Japanese Peptide Society Young Investigator`s Award
Association Membership(s) (3)：
The Japanese Peptide Society ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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