Rchr
J-GLOBAL ID:200901062346449725
Update date: Jan. 31, 2024 Takefumi Sone
ソネ タケフミ | Takefumi Sone
Affiliation and department: Job title:
Project Assistant Professor / Project Research Associate / Project Instructor
Research field (3):
Genetics
, Molecular biology
, Genomics
Research keywords (3):
recombinase
, Molecular cloning
, genome editing
Research theme for competitive and other funds (1): - 2015 - 2017 Development of genome editing technology with low off-target risk and high efficiency in human pluripotent stem cells
Papers (36): -
Takefumi Sone, Masashi Shin, Takehito Ouchi, Hiroki Sasanuma, Arei Miyamoto, Satoshi Ohte, Sho Tsukamoto, Mahito Nakanishi, Hideyuki Okano, Takenobu Katagiri, et al. Dual usage of a stage-specific fluorescent reporter system based on a helper-dependent adenoviral vector to visualize osteogenic differentiation. Scientific reports. 2019. 9. 1. 9705-9705
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Tetsuya Akiyama, Naoki Suzuki, Mitsuru Ishikawa, Koki Fujimori, Takefumi Sone, Jiro Kawada, Ryo Funayama, Fumiyoshi Fujishima, Shio Mitsuzawa, Kensuke Ikeda, et al. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons. EBioMedicine. 2019. 45. 362-378
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Naoko Kuzumaki, Yukari Suda, Chizuru Iwasawa, Michiko Narita, Takefumi Sone, Moe Watanabe, Aya Maekawa, Takuya Matsumoto, Wado Akamatsu, Katsuhide Igarashi, et al. Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease. Brain : a journal of neurology. 2019. 142. 6. 1675-1689
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Sho Yoshimatsu, Junko Okahara, Takefumi Sone, Yuta Takeda, Mari Nakamura, Erika Sasaki, Noriyuki Kishi, Seiji Shiozawa, Hideyuki Okano. Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system. Scientific reports. 2019. 9. 1. 1528-1528
- Tabata Y, Imaizumi Y, Sugawara M, Andoh-Noda T, Banno S, Chai M, Sone T, Yamazaki K, Ito M, Tsukahara K, et al. T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease. Stem cell reports. 2018. 11. 5. 1171-1184
more... MISC (53): - 曽根岳史, 田中泰圭, 太田悦朗, 細谷誠, 馬場庸平, 一柳直希, 日暮憲道, 廣瀬伸一, 岡野栄之. 疾患患者由来iPS細胞を用いた疾患モデル研究のためのTALENによるゲノム編集. 再生医療. 2015. 14. 321
- 細谷誠, 藤岡正人, 渡部孝太郎, 岡本理志, 曽根岳史, 松永達雄, 赤松和士, 小川郁, 岡野栄之. 患者由来PENDRED症候群特異的iPS細胞を用いたヒト内耳PENDRIN陽性細胞の解析. 再生医療. 2015. 14. 215
- 曽根岳史, 朴聖俊, 田中泰圭, 太田悦朗, 日暮憲道, 中井謙太, 廣瀬伸一, 廣瀬伸一, 岡野栄之. ゲノム編集した患者由来疾患iPS細胞の全ゲノム解析によって明らかになったこと. 日本生化学会大会(Web). 2015. 88th. 2W12-P-3 (WEB ONLY)
- 曽根岳史, 田中泰圭, 太田悦朗, 一柳直希, 日暮憲道, 廣瀬伸一, 岡野栄之. 疾患患者由来iPS細胞を用いた疾患モデル研究のためのゲノム編集. 日本分子生物学会年会プログラム・要旨集(Web). 2014. 37th. 1P-0921 (WEB ONLY)
- 曽根岳史, 進正史, 笹沼寛樹, 大手聡, 片桐岳信, 三谷幸之介. 成熟骨芽細胞をモニターできる新しい蛍光タンパク質レポーターシステムの開発. 日本骨代謝学会学術集会プログラム抄録集. 2012. 30th. 254
more... Patents (5): -
生細胞内の特定タンパク質の定量方法および標準蛍光マイクロビーズの作製方法
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タンパク質溶液の調製方法、当該タンパク質溶液、当該タンパク質溶液を利用したモノクローナル抗体の作製方法及び当該モノクローナル抗体
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新規なバイオビーズの作製方法
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外来性遺伝物質又は生理活性物質を細胞内へ導入する新規な方法
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Method For Introduction Of An Exogenous Genetic Substance Or A Physiologically Active Compound
Books (9): - 2. Multigene assembly for construction of synthetic operons: Creation and delivery of an optimized all-in-one expression construct for generating mouse iPS cells. <I>In:</I> Primary and Stem Cells: Gene Transfer Technologies and Applications
John Willey & Sons, Inc. Hoboken, NJ 2011 ISBN:9780470610749
- 第2章 遺伝子クローニング 6. Gateway・Multisite Gatewayクローニング法. <I>In:</I> 「新遺伝子工学ハンドブック(改訂第5版)」実験医学別冊
羊土社 東京 2010 ISBN:9784758101776
- 8. 細胞への複数遺伝子の導入と発現量の制御 <I>In:</I> 「Gatewayを用いた遺伝子導入マニュアル」
シュプリンガー・ジャパン株式会社 2009 ISBN:9784431100706
- 21. Cell engineering using integrase and recombinase systems. <I>In:</I> Emerging Technology Platforms for Stem Cells
John Willey & Sons, Inc. Hoboken, NJ 2009 ISBN:9780470146934
- 第4章 組換えタンパク質の発現と精製のコツ 3. タンパク質発現系 -発現クローンの構築: Gateway®/MultiSite Gateway®法 <I>In:</I> 「タンパク質精製と取扱のコツ」実験医学別冊
羊土社 東京 2007 ISBN:9784758101684
more... Education (3): - 1996 - 1999 Kyoto University Graduate School of Agriculture Division of Agricultural Chemistry
- 1994 - 1996 Kyoto University Graduate School of Agriculture Division of Agricultural Chemistry
- 1990 - 1994 Kyoto University Faculty of Agriculture Department of Agricultural Chemistry
Professional career (3): - 博士(農学) (京都大学大学院)
- 修士(農学) (京都大学大学院)
- 学士(農学) (京都大学)
Work history (8): - 2013/01/01 - Keio University Department of Physiology, School of Medicine Project Assistant Professor
- 2011/01/01 - 2012/12/31 Saitama Medical University Research Center of Genomic Medicine Assistant Professor
- 2007/04/01 - 2010/12/31 Osaka University Research Institute for Microbial Deseases Assistant Professor
- 2004/04/01 - 2007/03/31 Osaka University Research Institute for Microbial Deseases Assistant Professor
- 2001/12/01 - 2004/03/31 Osaka University Research Institute for Microbial Deseases Teacher
- 2001/07/01 - 2001/11/30 Osaka University Graduate School of Engineering, Division of Applied Biotechnology Research Assistant
- 1999/11/01 - 2001/05/31 BRAIN Osaka University, Faculty of Applied Biotechnology Postdoctoral fellow
- 1999/04/01 - 1999/10/31 Osaka University Faculty of Engineering, Department of Applied Biotechnology Teaching Assistant
Show all
Awards (1): - 2003/09/16 - 日本生物工学会 日本生物工学会論文賞
Association Membership(s) (3):
Japan Society for Bioscience, Biotechnology, and Agrochemistry
, The Molecular Biology Society of Japan
, The Japanese Society for Regenerative Medicine
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