SUZUKI Mamoru

スズキマモル | SUZUKI Mamoru

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/40280507.ja.html

Research field (1)： Structural biochemistry

Research keywords (10)：タンパク質結晶学 , X線結晶学 , シンクロトロン放射光 , 構造生物学 , 生物マシーナリー , タンパク質字結晶学 , セレノメチオニン , 多波長異状分散法 , 多波長異常分散法 , 蛋白質結晶構造解析

Research theme for competitive and other funds (12)：

2020 - 2023 X線結晶学による甲殻類急性ウイルス血症の感染機構の解明
2019 - 2023 Intracellular function and new extracellular signaling pathways of CCN proteins and their common molecular base
2020 - 2022 The development of new antibody drug discovery design by means of the bond replacement system based on the structure information
2017 - 2019 Exploration of pathogenicity caused by association and antigenicity of fibrous protein polymers present on the bacterial cell surface
2015 - 2018 Catechol-O-methyltransferase Enhancer

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Papers (153)：

Katsuki Takebe, Mamoru Suzuki, Yumiko Hara, Takuya Katsutani, Naomi Motoyoshi, Tadashi Itagaki, Shuhei Miyakawa, Kuniaki Okamoto, Kaori Fukuzawa, Hiroko Kobayashi. New Catalytic Residues and Catalytic Mechanism of the RNase T1 Family. ACS Bio & Med Chem Au. 2024
Tetsuya Masuda, Mamoru Suzuki, Masayuki Yamasaki, Bunzo Mikami. Subatomic structure of orthorhombic thaumatin at 0.89 Å reveals that highly flexible conformations are crucial for thaumatin sweetness. Biochemical and biophysical research communications. 2024. 703. 149601-149601
Katsuki Takebe, Mamoru Suzuki, Takeshi Sangawa, Naomi Motoyoshi, Tadashi Itagaki, Kana Kashima, Narikazu Uzawa, Hiroko Kobayashi. Identification of the Acidification Mechanism of the Optimal pH for RNase He1. Biological and Pharmaceutical Bulletin. 2023. 46. 12. 1778-1786
Takeshi Murakawa, Kazuo Kurihara, Mitsuo Shoji, Naomine Yano, Katsuhiro Kusaka, Yoshiaki Kawano, Mamoru Suzuki, Yasuteru Shigeta, Takato Yano, Motoyasu Adachi, et al. Neutron Crystallography of a Semiquinone Radical Intermediate of Copper Amine Oxidase Reveals a Substrate-Assisted Conformational Change of the Peptidyl Quinone Cofactor. ACS Catalysis. 2023. 12403-12413
Katsuki Takebe, Mamoru Suzuki, Takao Kuwada-Kusunose, Satoko Shirai, Kaori Fukuzawa, Tomoko Takamiya, Narikazu Uzawa, Hiroshi Iijima. Structural and Computational Analyses of the Unique Interactions of Opicapone in the Binding Pocket of Catechol O-Methyltransferase: A Crystallographic Study and Fragment Molecular Orbital Analyses. Journal of Chemical Information and Modeling. 2023

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MISC (90)：

小林弘子, 武部克希, 千田正, 元吉尚美, 板垣正, 鵜澤成一, 鈴木守. Structure and antitumor activity of 12-residue variants of RNase He1 derived from Yamabushitake mushrooms. 日本薬学会年会要旨集(Web). 2024. 144th
武部克希, 桑田(楠瀬)隆生, 鈴木守, 飯島洋, 飯島洋. Reaction mechanism of COMT and conformational changes induced by enhancer molecules. 日本薬学会年会要旨集(Web). 2024. 144th
小林弘子, 武部克希, 元吉尚美, 板垣正, 鵜澤成一, 鈴木守. Investigation of amino acid residues involved in the optimum pH of RNase He1 from Yamabushitake. 日本薬学会年会要旨集(Web). 2023. 143rd
小林弘子, 寒川剛, 武部克希, 元吉尚美, 板垣正, 鵜澤成一, 鈴木守. X-Ray Crystallographic Structure of RNase He1 in Complex with guanosine from Hericium erinaceus (Yamabushitake). 日本薬学会年会要旨集(Web). 2022. 142nd
佐藤啓子, 納屋昌実, 近藤好夫, 武部克希, 内藤真理子, 鈴木守, 今田勝巳, 石川岳志, 佐藤主税. 抗菌薬標的タンパク質の生化学歯周病細菌叢の病原性を抑える試み. 日本細菌学雑誌. 2021. 76. 1. 40-40

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Books (7)：

X線自由電子レーザーを用いたタンパク質の構造解析
日本結晶学会 2014
ジスルフィド結合形成(DsbB)
日本結晶学会 2014
XFEL微結晶構造解析-構造生物学の新時代(Frontiers of Protein Crystals)
タンパク質結晶の最前線(ジーエムシー出版監修杉山成) 2013
放射光施設フォトンファクトリー
共立出版 2004
6.タンパク質結晶X線回折実験における自動化
エヌ・ティー・エス 2004

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Works (3)：

細胞接着・細胞運動制御に関与するネクチン様分子の構造生物学的研究
2010 -
細胞接着装置構成タンパク質の構造生物学的研究
2008 -
細胞接着装置構成タンパク質の構造生物学的研究
2007 -

Professional career (1)：

博士(理学) (北海道大学)

Work history (1)：

2004/03 - 2007/03 Osaka University Institute for Protein Research

Awards (2)：

2007 - 平成18年度大阪大学教育・研究功績賞
2006 - 大阪大学共通教育賞

Association Membership(s) (2)：

American Crystallographic Association , American Crystallographic Association

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