Tomoda Hiroshi

トモダヒロシ | Tomoda Hiroshi

Affiliation and department：
Job title： Professor

Research field (4)： Pharmacology , Pharmaceuticals - health and biochemistry , Pharmaceuticals - chemistry and drug development , Molecular biochemistry

Research keywords (6)：生物有機化学 , 脂質生化学 , 微生物天然物化学 , Bioorganic chemistry , Lipid biochemistry , Microbial natural products chemistry

Research theme for competitive and other funds (10)：

2002 - 2006 抗感染症薬の検索と応用
2002 - 2006 Screen for anti-infective drugs and their biomedical application
1983 - 脂質代謝阻害剤の検索とその応用
1983 - Screen for lipid metabolism inhibitors and their biomedical application
生活習慣病予防治療薬の開拓研究

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Papers (172)：

Ryuji Uchida, Ariko Kondo, Akiho Yagi, Kenichi Nonaka, Rokurou Masuma, Keisuke Kobayashi, Hiroshi Tomoda. Simpotentin, a new potentiator of amphotericin B activity against Candida albicans, produced by Simplicillium minatense FKI-4981. The Journal of antibiotics. 2019. 72. 3. 134-140
Takashi Fukuda, Takun Furukawa, Keisuke Kobayashi, Kenichiro Nagai, Ryuji Uchida, Hiroshi Tomoda. Helvamide, a new inhibitor of sterol O-acyltransferase produced by the fungus Aspergillus nidulans BF-0142. The Journal of antibiotics. 2019. 72. 1. 8-14
Nobuhiro Koyama, Hiroshi Tomoda. MS network-based screening for new antibiotics discovery. The Journal of antibiotics. 2019. 72. 1. 54-56
Ohshiro T, Seki R, Fukuda T, Uchida R, Tomoda H. Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307. The Journal of antibiotics. 2018. 71. 12. 1000-1007
Keisuke Kobayashi, Satoshi Ohte, Taichi Ohshiro, Narihiro Ugaki, Hiroshi Tomoda. A Mixture of Atropisomers Enhances Neutral Lipid Degradation in Mammalian Cells with Autophagy Induction. Scientific reports. 2018. 8. 1. 12099-12099

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MISC (184)：

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Patents (42)：

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Books (8)：

化学療法学(改訂第2版): 病原微生物・がんと戦う
南江堂 2018 ISBN:4524403493
化学系薬学III(スタンダード薬学シリーズII-3): 自然が生み出す薬物
東京化学同人 2016 ISBN:4807917072
「酵素阻害剤及び受容体作用物質」微生物薬品化学 改訂第4版 (上野芳夫、大村智監修)
南江堂 2003
'Discovery of lead compounds for medicines from microorganisms'. Biotechnology in the 21st Century
Indonesia Biotechnology Consortium 2002
“Discovery of lead compounds for medicines from microorganisms”. Biotechnology in the 21st Century
Indonesia Biotechnology Consortium 2002

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Lectures and oral presentations (25)：

Study of PRD125, a SOAT2-Selective Inhibitor, in Atherogenic Mouse Model.
(AHA 2018 2018)
微生物代謝産物のネットワークを基盤とした新規天然物の探索
(高磁場・高感度NMR 利活用促進のための天然物分野シンポジウム2018 2018)
微生物資源からの抗酸菌症治療薬の開拓
(第101回日本細菌学会関東支部総会 2018)
チオペプチド系及びストレプトグラミン系抗生物質の非結核性抗酸菌に対する抗菌作用
(第101回日本細菌学会関東支部総会 2018)
真菌が生産する三環性化合物カップリング酵素の精製
(第101回日本細菌学会関東支部総会 2018)

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Works (8)：

脂質代謝阻害剤の探索研究
1997 - 現在
脂質代謝を制御する機能分子プローブの創製
2004 - 2007
天然素材による抗感染症薬の創製と基盤研究
2002 - 2006
微生物由来の新しい医薬品素材の開拓
1996 - 2000
Discovery and production of lead compounds for medicines from microorganisms
1996 - 2000

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Education (4)：

- 1983 The University of Tokyo
- 1983 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
- 1978 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
- 1978 The University of Tokyo Faculty of Pharmaceutical Science

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (12)：

2002 - 2002 Kitasato University Kitasato Institute for Life Sciences
1996 - 2001 北里研究所生物機能研究所副所長
1996 - 2001 Associate director, The Kitasato Institute
2001 - - 北里大学北里生命科学研究所教授
2001 - - Professor Kitasato University

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Committee career (1)：

2000 - 2003 日本薬学会幹事、代議員

Awards (3)：

2001 - 日本薬学会学術振興賞
2000 - ジョンズホプキンススカラー(Johns Hopkins Society of Scholars)
1997 - 住木・梅澤記念賞

Association Membership(s) (7)：

日本マリンバイオテクノロジー , 日本細菌学会 , 日本放線菌学会 , 日本脂質生化学研究会 , 日本生化学会 , 日本薬学会 , Society for Industrial Microbiology

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