Rchr
J-GLOBAL ID:200901086778834693
Update date: Nov. 12, 2024 Tomita Yutaka
トミタ ユタカ | Tomita Yutaka
Affiliation and department: Job title:
Chief researcher,Director of department of neurology
Other affiliations (1): Research field (4):
Neurology
, Clinical pharmacy
, Physiology
, Neuroscience - general
Research keywords (10):
再生医療
, 認知症
, 神経変性疾患
, 脳血管障害
, 神経内科学
, Regenerative medicine
, dementia
, Neuro degenerative diseases
, Cerebrovasucular diseases
, Neurology
Research theme for competitive and other funds (16): - 2021 - 2024 中枢神経障害下でのNG2グリアの挙動と髄鞘の再生機序の解明
- 2020 - 2023 オプトジェネティクスを用いた神経血管連関における微小血流調節機序と虚血時の反応性
- 2014 - 2018 A role of astrocyte in neuro-glio-vascular unit concerning cerebral microcirculation
- 2015 - 2018 脳虚血時神経血管カップリングへのマイクログリアの関与の検討
- 2012 - 2015 脳局所脳虚血モデルを用いたNeurovascular Couplingの検討
- 2009 - 2011 マウス局所脳虚血モデルへの神経堤由来細胞移植の効果の検討
- 2008 - 2010 Stat3 phosphorylation in pathogenesis of chronic cerebral ischemia
- 2007 - 2008 Investigation of involvement of ERK signal transduction pathway in the development of infact size after focal cerebral ischemia
- 2005 - 2008 Studies on cortical spreading depression and changes in brain capillary blood flow in acute phase of brain ischemia or aura in acute migraine
- 2006 - アルツハイマー病の早期診断、VsRADソフトウェアによる検討
- 2006 - Early diagnosis of Alzheimer diseases using VsRAD software
- 1998 - 1999 Platelet adhesion to endothelial cells in vitro, observation with video-enhanced contrast (VEC) microscopy
- 1998 - マウス脳虚血モデルにおける長期微小循環動態の検討
- 1998 - Long term investigation of micro-circulation in focal ischemia model in mouse brain
- 1993 - 神経内科疾患患者の診断、治療
- 1993 - Diagnosis and treatment of patients of neurology
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Papers (88): -
Hiroki Suzuki, Juri Murata, Miyuki Unekawa, Iwao Kanno, Yoshikane Izawa, Yutaka Tomita, Kenji F. Tanaka, Jin Nakahara, Kazuto Masamoto. Microfluctuations in Capillary Lumens Independent of Pericyte Lining Density in the Anesthetized Mouse Cortex. Microcirculation. 2024
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Miyuki Unekawa, Naoki Tsukada, Tsubasa Takizawa, Yutaka Tomita, Jin Nakahara, Yoshikane Izawa. Striatal Blood Flow Changes by Middle Cerebral Artery Occlusion and Its Effect on Neurological Deficits in Mice. Microcirculation (New York, N.Y. : 1994). 2024. e12861
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Juri Murata, Miyuki Unekawa, Yuya Kudo, Maho Kotani, Iwao Kanno, Yoshikane Izawa, Yutaka Tomita, Kenji F Tanaka, Jin Nakahara, Kazuto Masamoto. Acceleration of the Development of Microcirculation Embolism in the Brain due to Capillary Narrowing. Stroke. 2023. 54. 8. 2135-2144
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Miyuki Unekawa, Yutaka Tomita, Kazuto Masamoto, Iwao Kanno, Jin Nakahara, Yoshikane Izawa. Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice. Brain research. 2022. 1792. 148023-148023
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畝川 美悠紀, 塚田 直己, 滝沢 翼, 冨田 裕, 中原 仁, 伊澤 良兼. 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流動態変化と梗塞形成. 脳循環代謝. 2022. 34. 1. 121-121
more... MISC (61): -
Kwon S, Abe Y, Mushiake H, Unekawa M, Masamoto K, Tomita Y, Tanaka K. Optogenetic manipulation of mural cells evoked regional brain blood flow changes in the deep brain. IBRO Reports. 2019. 6. S536
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Y. Tomita, N. Hatakeyama, M. Unekawa, K. Tanaka, K. Matsui, N. Suzuki, I. Kanno, K. Masamoto, J. Nakahara. PB01-T04 Vasodilatory response to optogenetic activation of neurons or astrocytes in the anesthetized mouse cortex. Journal of Cerebral Blood Flow and Metabolism. 2019. 39. S1. 241-241
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M. Unekawa, Y. Tomita, Y. Izawa, C. Tang, K. Masamato, I. Kanno, K. Ikeda, K. Kawakami, N. Suzuki, J. Nakahara. PB03-L04 Effects of spreading depolarization on development of cerebral infarction after middle cerebral artery occlusion in Naþ,Kþ-ATPase a2 subunit-deficient mice. Journal of Cerebral Blood Flow and Metabolism. 2019. 39. S1. 440-441
- 正本和人, 須貸拓馬, 畝川美悠紀, 冨田裕, 菅野巖. in vivoマウス大脳微小血管の4Dイメージング. 脳神経外科速報. 2019. 29. 6. 622-628
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漆畑拓弥, 漆畑拓弥, 高橋真奈美, 田桑弘之, 下條雅文, 高堂裕平, 正本和人, 菅野巌, 富田裕, 伊藤浩, et al. 慢性低灌流マウスにおける神経機能障害メカニズムの解明. 脳循環代謝(Web). 2018. 30. 1
more... Patents (2): -
生体構成要素速度測定装置、及びそのプログラム
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血流測定装置
Books (3): - International Congress Series 1235
Elsevier 2002
- Maturation phenomenon in cerebral ischemia
Springer-Verlag 2001
- Ischemic blood flow in the brain
Springer-Verlag 2001
Lectures and oral presentations (46): -
Analysis of red blood cell velocity in intraparenchymal capillaries and arterial diameter in mice.
(第61回日本神経学会学術大会 2020)
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Optogenetic activation of neural and astrocytic control of vasodilation in the mouse cortex
(29th International Symposium on Cerebral Blood Flow, Metabolism & Function 2019)
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Optogenetic activation of neural and astrocytic control of vasodilation in the mouse cortex
(第60回日本神経学会学術大会 2019)
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Acceleration of red blood cells in intraparenchymal capillaries and dilation of arterial diameter in response to hypercapnia were diminished after passage of cortical spreading depression in anesthetized mice.
(2016)
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Dynamics of red blood cells in intraparenchymal capillaries and arterial diameter during cortical spreading depression observed with high-speed camera confocal fluorescence microscope in anesthetized mice.
(10th World Congress for Microcirculation 2015)
more... Education (1): - Keio University School of Medicine Depertment of Medicine
Professional career (1): Work history (10): - 2017 - 現在 医療法人 木南舎 理事長
- 2011 - 現在 冨田病院 院長
- 2009 - 現在 Keio University School of Medicine
- 2009 - 2010 冨田病院 副院長
- 2007 - 2009 Keio University School of Medicine
- 2005 - 2007 脳血管研究所・美原記念病院 神経内科 部長
- 2002 - 2005 パリ大学医学部 国立衛生医学研究所 特別研究員
- 2000 - 2002 さいたま市立病院 神経内科
- 1999 - 2000 Keio University School of Medicine
- 1993/04 - 1999 Keio University School of Medicine
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Association Membership(s) (8):
国際脳循環代謝学会
, 日本脳循環代謝学会
, 日本微小循環学会
, 日本頭痛学会
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, JAPAN SOCIETY FOR DEMENTIA RESEARCH
, THE JAPAN STROKE SOCIETY
, JAPANESE SOCIETY OF NEUROLOGY
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