GENGYO-ANDO KEIKO

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.dent.tohoku.ac.jp/field/morphology/02/index.html

Research field (2)： Neuroscience - general , Cell biology

Research keywords (4)：神経回路機能 , カルシウムイメージング , membrane traffic , C. elegans

Research theme for competitive and other funds (23)：

2021 - 2026 Development of X-logbot and Elucidation of Behavior Diagram using Sparse Modeling
2021 - 2023 A novel animal model of sarcopenia
2020 - 2023 Study on neural mechanism of swallowing by imaging
2017 - 2021 Molecular physiological study of impairment in endosome system
2015 - 2020 Development of Fluorescent Probes with Molecular Evolution Engineering

2014 - 2018 Study of neuronal network mechanism for habit learning using highly sensitive calcium probe

2015 - 2017 A study of neural circuit mechanism of voluntary behavior in C. elegans

2013 - 2015 Imaging analysis of neural circuit involved in voluntary behaviors in C. elegans

2013 - 2014 Next generation photostimulation system using tunable laser

2011 - 2013 線虫の出力系回路における神経活動の可視化と解析

2012 - 2012 Development of a next-generation photo-stimulation device

2010 - 2012 STUDY OF SYNAPTIC MODULATORY MECHANISMS IN RESPONSE TO STRESS MEDIATED BY 5-HT2A RECEPTOR

2010 - 2012 Functional study of Munc18 mutations associated with epilepsy

2008 - 2009 線虫遺伝子破壊による低分子量G蛋白質RABファミリーのゲノム機能解析

2007 - 2009 Functional analysis of Rab proteins involved in endocytic transport in multicellular organism.

2006 - 2007 線虫遺伝子破壊による低分子量G蛋白質RABファミリーのゲノム機能解析

2004 - 2005 線虫vps遺伝子群の網羅的遺伝子破壊によるリソソームの構築と輸送システムの解明

2002 - 2003 Functional analysis of Sec1/Munc-18 family involved in membrane traffic

2001 - 2002 逆遺伝学的アプローチによる線虫UNC-18ファミリーの系統的機能解析

1998 - 1999 神経伝達物質放出に関与する線虫UNC-18ファミリーの機能解析

1994 - 1994 神経伝達物質遊離に関与するunc-18マウス相同遺伝子の構造と機能

1993 - 1993 線虫アセチルコリン異常蓄積変異遺伝子unc-18の構造と機能

1990 - 1990 線虫Caenorhabditis elegansの太い線維形成機構

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Papers (72)：

Kanako Tominami, Tada-Aki Kudo, Takuya Noguchi, Yohei Hayashi, You-Ran Luo, Takakuni Tanaka, Ayumu Matsushita, Satoshi Izumi, Hajime Sato, Keiko Gengyo-Ando, et al. Physical Stimulation Methods Developed for In Vitro Neuronal Differentiation Studies of PC12 Cells: A Comprehensive Review. International journal of molecular sciences. 2024. 25. 2
Keiko Gengyo-Ando, Akane Osawa-Noguchi, Hideki Ando, Junichi Nakai. Functional analysis of epilepsy-linked pathogenic variants of the Munc18-1 gene in the inhibitory nervous system of Caenorhabditis elegans. microPublication biology. 2024. 2024
Keiko Gengyo-Ando, Masahiko Kumagai, Hideki Ando, Junichi Nakai. Domain 3a mutation of VPS33A suppresses larval arrest phenotype in the loss of VPS45 in Caenorhabditis elegans. microPublication biology. 2024. 2024
Keiko Gengyo-Ando, Minoru Tateyama, Shohei Mitani, Hideki Ando, Junichi Nakai. A humanized Caenorhabditis elegans model for studying pathogenic mutations in VPS45, a protein essential for membrane trafficking, associated with severe congenital neutropenia. microPublication biology. 2023
Kagari Akama, Kanami Ebata, Akiteru Maeno, Tomohito Taminato, Shiori Otosaka, Keiko Gengyo-Ando, Junichi Nakai, Kyo Yamasu, Akinori Kawamura. Role of somite patterning in the formation of Weberian apparatus and pleural rib in zebrafish. Journal of anatomy. 2020. 236. 4. 622-629

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MISC (72)：

三谷昌平, 吉名佐和子, 堀沙耶香, 末廣勇司, 出嶋克史, 岩田悟, 中台枝里子, 安藤恵子, 本橋智子. 線虫遺伝学を用いたヒト相同遺伝子の機能解析. 東京女子医科大学総合研究所紀要. 2017. 36. 24-25
茂木優貴, 安藤恵子, 沖篤志, 岩井陽一, 毛内拡, 平瀬肇, 大倉正道, 中井淳一. G-CaMP7発現マウスを用いた大脳皮質神経活動のミクロ、マクロ解析法. 日本生理学雑誌. 2016. 78. 3. 56-56
茂木優貴, 茂木優貴, 安藤恵子, 安藤恵子, 沖篤志, 沖篤志, 岩井陽一, 毛内拡, 平瀬肇, 平瀬肇, et al. G-CaMP7発現マウス大脳皮質脳細胞活動の細胞-領野スケール長期イメージング実験解析法. 日本生化学会大会(Web). 2015. 88th. 1LBA113 (WEB ONLY)-[1LBA113]
茂木優貴, 安藤恵子, 沖篤志, 岩井陽一, 毛内拡, 平瀬肇, 大倉正道, 中井淳一. G-CaMP7発現マウス大脳皮質脳細胞活動の細胞-領野スケール長期イメージング実験解析法. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [1LBA113]-[1LBA113]
野村一也, 松田采子, 金氣菜々子, 出嶋克史, 村田大輔, 野村和子, 三谷昌平, 安藤恵子, 大倉隆司. CDG(先天性グリコシル化異常症Congenital Disorders of Glycosylation)モデル生物としての線虫C.elegansの有用性 DPAGT1(ALG7)遺伝子破壊株を中心とした解析. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [3P0285]-[3P0285]

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Patents (1)：

線虫を用いた物質の生理活性評価法

Lectures and oral presentations (2)：

in vivo calcium imaging, membrane trafficking and taste preference
(2022 8th International Conference on Mechatronics and Robotics Engineering (ICMRE) 2022)
Membrane trafficking
(21th Yonsei Dental International Symposium 2022)

Education (3)：

1988 - 1991 Okayama University
1986 - 1988 Okayama University
1982 - 1986 Okayama University Faculty of Science

Professional career (1)：

Ph D (Okayama University)

Work history (9)：

2019/04 - 現在 Tohoku University Graduate School of Dentistry
2014/10 - 2019/03 Saitama University Graduate School of Science and Engineering
2014/04 - 2014/09 Saitama University Graduate School of Science and Engineering
2009/08 - 2014/03 Saitama University
1996/06 - 2009/07 Tokyo Women's Medical University

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Association Membership(s) (4)：

日本神経科学学会 , 日本分子生物学会 , The Japan Neuroscience Society , The Molecular Biology Society of Japan

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