Rchr
J-GLOBAL ID:201001070959792752
Update date: Nov. 05, 2022
Into Takeshi
イントウ タケシ | Into Takeshi
Affiliation and department:
Research keywords (6):
damage-associated molecular patterns(DAMPs)
, pathogen-associated molecular patterns (PAMPs)
, pattern recognition receptor
, 歯周病
, 細胞内シグナル伝達
, 口腔の自然免疫系
Research theme for competitive and other funds (13):
- 2022 - 2025 Analysis of the role of phosphatidylserine-binding proteins accumulated in dental plaque and their relevance to the onset of periodontitis
- 2022 - 2025 GBPsによるLPS認識が歯周炎ならびに炎症性腸疾患に及ぼす病因的役割の解明
- 2018 - 2020 自己免疫性唾液腺炎の司令塔:MyD88依存的シグナルによる三次リンパ組織形成機構
- 2014 - 2016 小胞輸送制御因子「インターセクチン」による唾液腺での抗菌因子産生制御機構の解析
- 2012 - 2015 Elucidation of the mechanism to improve the cleft palate phenotype with the molecular target drug
- 2011 - 2013 TLR/TACI-MyD88経路による唾液腺のIgA産生形質細胞の出現制御機構
- 2009 - 2011 メカニカルストレス下の歯周病原因子による歯根膜線維芽細胞のシグナル伝達機構の解明
- 2007 - 2009 Development of new therapy for periodontal disease based on regulating exocytosis
- 2008 - 2008 口腔自然免疫機構における多量体型免疫グロブリン受容体pIgRの役割の解明
- 2007 - 2008 一酸化窒素による細菌感染時応答の時間的・空間的制御機構の解明
- 2007 - 2008 歯肉上皮機能の分子機構の解明とその制御に関する研究
- 2006 - 2007 歯周病発症におけるチオレドキシンの役割と作用メカニズム
- 2004 - 2005 口腔微生物由来分子パターンによって誘導される細胞の生死のメカニズム
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Papers (21):
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Taiki Mori, Hideo Kataoka, Gen Tanabe, Takeshi Into. Solubility affects IL-1β-producing activity of the synthetic candidalysin peptide. PloS one. 2022. 17. 8. e0273663
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Taiki Mori, Hideo Kataoka, Takeshi Into. Effect of Myd88 deficiency on gene expression profiling in salivary glands of female non-obese diabetic (NOD) mice. Journal of oral biosciences. 2021. 63. 2. 192-198
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Hideo Kataoka, Taiki Mori, Takeshi Into. Citrobacter koseri stimulates dendritic cells to induce IL-33 expression via abundant ATP production. Journal of medical microbiology. 2021. 70. 3
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Hideo Kataoka, Ayumi Saeki, Akira Hasebe, Ken-Ichiro Shibata, Takeshi Into. Naringenin suppresses Toll-like receptor 2-mediated inflammatory responses through inhibition of receptor clustering on lipid rafts. Food science & nutrition. 2021. 9. 2. 963-972
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Into T, Niida S, Shibata KI. MyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling. Scientific reports. 2018. 8. 1. 14272
more...
MISC (2):
Work history (1):
- 2019/02 - 現在 Asahi University School of Dentistry
Association Membership(s) (5):
JAPANESE SOCIETY FOR IMMUNOLOGY (JSI)
, American Association of Immunologists
, 日本細菌学会
, 歯科基礎医学会
, International Association for Dental Research (IADR)
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