Shimizu Shinichi

シミズシンイチ | Shimizu Shinichi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/50463724.ja.html

Research field (5)： Medical systems , Tumor diagnostics and therapeutics , Tumor biology , Biomedical engineering , Radiology

Research keywords (19)： Radiation bioeffect simulation , Radiaion biology , ultra high dose irradiation , 強度変調放射線治療 , Proton therapy , Particle therapy , Radiotherapy , Reat time tumor tracking radiotherapy , Image guided radiotherapy , 電子線トラック解析 , 核医学診断技術 , 非線形最適化 , モンテカルロ法 , Stereotactic body radiotherapy , プラスチック検出器 , 炎症性発癌 , スポットスキャン , 低酸素細胞 , 量子線シミュレーション

Research theme for competitive and other funds (20)：

2023 - 2027 患者体内リアルタイム陽子線照射線量分布可視化システムの基盤創成
2022 - 2026 放射線治療効果向上を目指した新規細胞標的~インフルエンサー・セルの探索~
2019 - 2024 Research and development about helium and proton hybrid system with proton CT and Immuno-radiotherapy
2020 - 2023 Marker-less volume imaging technique for real-time tumor tracking radiation therapy
2019 - 2022 陽子線治療におけるパラメトリックDVH予測モデルの構築と治療高度化の試み

2017 - 2022 Research on standard methods and data for evaluating the cost-effectiveness of particle therapy

2017 - 2022 量子線手術(クオンタム・ビーム・サージェリー)における治療術中の迅速な判断・決定を支援するための診断支援機器・システム開発

2018 - 2021 Real-time volumetric image generation based on CT deformation driven by simultaneous monitoring of internal landmarks and object surface

2018 - 2021 Development of minimum invasive real-time markerless image guided radiotherapy technique using minimum space information.

2016 - 2020 Development of robust proton beam scanning treatment technology considering target heterogeneity and movement

2016 - 2020 Development of therapeutic response-guided radiotherapy based on dose evaluation using CBCT images

2015 - 2019 Research and Development of Helium and Proton Hybrid Beam Therapy

2015 - 2018 Attempt of 4D-IGRT by Volume Matching Method of 4D-CBCT and Therapy Planning CT

2014 - 2017 Development of respiratory phase segmentation algorithm based on the analysis of internal target motion for high accurate respiratory-gated radiation therapy

2012 - 2014 Approaches to the 4D-CBCT using 2 axis fluoroscopic X-ray

2009 - 2012 Research for Real-time Tracking Medical Science

2009 - 2012 Clinical trials for the establishment of standard radiation therapy methods and the selection of radiosensitive tumors in early cancer patients

2007 - 2009 Development of a Vocabulary Test Battery Estimating English Skills and Proficiency : Integrating Vocabulary Size, Organization, and Access Speed

2005 - 2009 Basic Research for four-dimensional stereotactic radiotherapy

2006 - 2008 Interactive Radiotherapy

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Papers (391)：

Kentaro Nishioka, Takayuki Hashimoto, Takashi Mori, Yusuke Uchinami, Rumiko Kinoshita, Norio Katoh, Hiroshi Taguchi, Koichi Yasuda, Yoichi M Ito, Seishin Takao, et al. A Single-Institution Prospective Study To Evaluate the Safety and Efficacy of Real- Time Image-Gated Spot-Scanning Proton Therapy (RGPT) for Prostate Cancer. Advances in radiation oncology. 2024. 9. 5. 101464-101464
Kazuhiko Hayashi, Osamu Suzuki, Yushi Wakisaka, Koji Ichise, Hirofumi Uchida, Makoto Anzai, Azusa Hasegawa, Yuji Seo, Shinichi Shimizu, Takayoshi Ishii, et al. Prognostic analysis of radiation-induced liver damage following carbon-ion radiotherapy for hepatocellular carcinoma. Radiation oncology (London, England). 2024. 19. 1. 51-51
Yue Dong, Keisuke Tamari, Maiko Kishigami, Shohei Katsuki, Kazumasa Minami, Shotaro Tatekawa, Shinichi Shimizu, Masahiko Koizumi, Kazuhiko Ogawa. Irradiated Cell-derived Exosomes Enhance Cell Proliferation and Radioresistance via the MAPK/Erk Pathway. Cancer genomics & proteomics. 2024. 21. 1. 12-17
Keisuke Tamari, Kazumasa Minami, Shotaro Tatekawa, Yuji Seo, Takahito Fukusumi, Hidenori Tanaka, Motoyuki Suzuki, Hirotaka Eguchi, Yukinori Takenaka, Takero Hirata, et al. Circulating Plasma Exosomal PD-L1 Predicts Prognosis of Head and Neck Squamous Cell Carcinoma After Radiation Therapy. Advances in Radiation Oncology. 2023
玉利慶介, 立川章太郎, 瀬尾雄二, 林和彦, 福角隆仁, 田中秀憲, 鈴木基之, 江口博孝, 竹中幸則, 平田岳郎, et al. 頭頸部がん治療新世紀を拓く基礎研究・橋渡し研究血液中のPDL1測定による頭頸部癌放射線治療後の予後予測. 頭頸部癌. 2023. 49. 2. 85-85

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MISC (63)：

林和彦, 鈴木修, 立川章太郎, 平田岳郎, 玉利慶介, 塩見浩也, 瀬尾雄二, 礒橋文明, 清水伸一, 小川和彦. 転移性肺腫瘍に対するサイバーナイフを用いた定位放射線治療の成績. 日本放射線腫瘍学会高精度放射線外部照射部会学術大会プログラム・抄録集. 2022. 35th
大塚愛美, 安田耕一, 湊川英樹, 出倉康裕, 青山英史, 清水伸一, 鈴木隆介, 宮本直樹, 清水伸一, 鈴木崇祥, et al. 強度変調放射線治療(IMRT)を行った下咽頭癌における再発症例の検討. Japanese Journal of Radiology. 2022. 40. Supplement
宮崎智彦, 安田耕一, 志藤元泰, 小泉富基, 藤田祥博, 高橋周平, 湊川英樹, 大塚愛美, 加藤徳雄, 清水伸一, et al. SMARCB1欠損篩骨洞癌に対する強度変調陽子線治療症例報告と文献レビュー. 北海道放射線医学雑誌. 2021. 1. 1-6
橋本孝之, 森崇, 西岡健太郎, 打浪雄介, 安田耕一, 木下留美子, 田口大志, 加藤徳雄, 清水伸一, 青山英史. Proton beam therapy for reirradiation in pediatric cancer. 日本小児血液・がん学会雑誌(Web). 2021. 58. 2
藤田祥博, 加藤徳雄, 田口大志, 打浪雄介, 西岡健太郎, 森崇, 湊川英樹, 安田耕一, 清水伸一, 青山英史. 肝細胞癌陽子線治療前MRIにおけるばらつきの小さいADC値指標の検討:治療効果予測に向けた前段階の研究. 日本放射線腫瘍学会高精度放射線外部照射部会学術大会プログラム・抄録集. 2021. 34th

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Patents (18)：

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Professional career (1)：

博士(医学) (北海道大学)

Work history (2)：

2021/10 - 現在 Osaka University Department of Carbon Ion Radiotherapy, Graduate School of Medicine Professor
2016/10 - 2021/03 Hokkaido University Graduate School of Medicine Faculty of Medicine Department of Radiation Oncology Professor

Awards (2)：

2019 - 公益財団法人中外創薬科学財団 JCA-CHAAO賞動体追跡技術と同期照射技術を用いた高精度放射線治療の開発と臨床研究
2018/02 - 一般社団法人科学技術と経済の会(JATES) 技術経営・イノベーション賞科学技術と経済の会会長賞

Association Membership(s) (5)：

日本緩和医療学会 , JAPAN SOCIETY OF MEDICAL PHYSICS , 米国放射線腫瘍学会 , JAPAN RADIOLOGICAL SOCIETY , JAPANESE SOCIETY FOR THERAPEUTIC RADIOLOGY AND ONCOLOGY

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