Rchr
J-GLOBAL ID:201401079009149876
Update date: May. 08, 2024
Hosomichi Kazuyoshi
ホソミチ カズヨシ | Hosomichi Kazuyoshi
Affiliation and department:
Job title:
Professor
Homepage URL (2):
https://toyaku-ls-genomics.com
,
https://scholar.google.com/citations?user=tCECg-8AAAAJ&hl=ja&oi=ao
Research field (4):
Systems genomics
, Medical biochemistry
, Genomics
, Genetics
Research theme for competitive and other funds (25):
- 2023 - 2027 口腔癌の新規抗体薬の開発 ~NOTCH1阻害薬は扁平上皮癌と腺様嚢胞癌の治療を変える~
- 2023 - 2026 Research and development of new risk assessment methods using analysis of multi-layered omics datasets for precision medicine of common diseases
- 2023 - 2025 Microbiome analysis to elucidate the life and culture of the Waorani people
- 2022 - 2025 Development of a framework for improving lifestyle-related diseases targeting the mutual network of gut microbiota
- 2021 - 2025 免疫チェックポイント阻害薬の治療有効性・抵抗性の要因評価~宿主腫瘍HLA環境解析
- 2019 - 2025 遺伝統計学に基づく日本人集団のゲノム個別化医療の実装
- 2021 - 2023 HLAハプロタイプの多様性にもとづくヤポネシア人進化の解明
- 2020 - 2023 トロンボポエチン受容体作動薬ロミプロスチムの造血への影響とDNA修復効果の検証
- 2019 - 2023 Comprehensive analysis of genetic risk factors for diabetes in in the diabetes population surge zone: The Bangladesh cohort study
- 2020 - 2022 Advantage of cohort study with integrated HLA information for personalized medicine
- 2019 - 2022 横断的オミクス解析と全ゲノムシークエンスを駆使した疾患病態と組織特異性の解明
- 2019 - 2022 Identification of autoantigens presented by specific HLA class I alleles in aplastic anemia
- 2019 - 2022 Discovering Novel Disease Mechanisms of Cardiac Sarcoidosis Using Transcriptome Sequencing Deribed from Human Cardiac Biopsy Sample
- 2019 - 2021 Evolution of Yaponesians based on the HLA gene polymorphisms
- 2018 - 2021 集学的な機能ゲノミクスによる希少MODYの成因探索
- 2016 - 2021 Genetic analysis of neo-self
- 2017 - 2019 HLA-omics-based pharmacogenomics for adverse drug reactions in genome cohort studies
- 2017 - 2019 Deciphering Novel Disease Mechanism in Familial Hypertrophic Cardiomyopathy
- 2015 - 2018 Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus
- 2014 - 2017 High-throughput sequencing method of the KIR haplotype for clinical applications
- 2010 - 2015 HLA genome diversity analyses by resequencing
- 2014 - 2015 HLA遺伝子完全配列決定パイプラインの構築
- 2012 - 2014 Protocol for exome sequencing analysis to identify a causal gene of familial IgA nephropathy
- 2009 - 2011 Elucidation of MHC polymorphism information in cynomolgus macaque(Macaca Fascicularis)
- 2009 - 2010 Identification of the genetic factor against influenza virus infection in the chicken MHC region.
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Papers (161):
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Kouyuki Hirayasu, Seik-Soon Khor, Yosuke Kawai, Mihoko Shimada, Yosuke Omae, Gen Hasegawa, Yuko Hashikawa, Hiromu Tanimoto, Jun Ohashi, Kazuyoshi Hosomichi, et al. Identification of the hybrid gene LILRB5-3 by long-read sequencing and implication of its novel signalling function. Frontiers in Immunology. in press. 2024
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Vanessa I. Romero, Samantha Sáenz, Benjamín Arias-Almeida, Daniela DiCapua, Kazuyoshi Hosomichi. AARS and CACNA1A mutations: diagnostic insights into a case report of uncommon epileptic encephalopathy phenotypes in two siblings. Frontiers in Neurology. 2024. 15
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Samantha Saenz Hinojosa, Timothy Adrian Jinam, Kazuyoshi Hosomichi, Vanessa I Romero. HLA allelic diversity in the Waorani population of Ecuador: Its significance to their ancestry and migration. Human Immunology. 2024. 110771-110771
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Yukio Horikawa, Kazuyoshi Hosomichi, Daisuke Yabe. Monogenic diabetes. Diabetology International. 2024
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Hironori Yamamoto, Yohei Miyashita, Hitoshi Minamiguchi, Kazuyoshi Hosomichi, Shohei Yoshida, Hidetaka Kioka, Haruki Shinomiya, Haruno Nagata, Kenji Onoue, Masato Kawasaki, et al. Human leukocyte antigen-DQ risk heterodimeric haplotypes of left ventricular dysfunction in cardiac sarcoidosis: an autoimmune view of its role. Scientific reports. 2023. 13. 1. 19767-19767
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MISC (26):
Patents (3):
Books (6):
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実験医学増刊 ポストGWAS時代の遺伝統計学
羊土社 2023 ISBN:9784758104104
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ヒトゲノム事典
一色出版 2021 ISBN:4910389121
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遺伝/ゲノム看護
医歯薬出版 2018 ISBN:9784263236994
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実験医学別冊 次世代シークエンス解析スタンダード NGSのポテンシャルを活かしきるWET&DRY
羊土社 2014 ISBN:9784758101912
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遺伝子図鑑
悠書館 2013 ISBN:9784903487793
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Lectures and oral presentations (42):
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ヒトゲノムの解読困難領域 HLAおよびKIR遺伝子の解析
(第31回日本組織適合性学会大会 ランチョンセミナー 2023)
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Genetic Dissection of Early-Onset Non-Type 1 Diabetes
(IDF-WPR Congress 2023 / 15th Scientific Meeting of AASD 2023)
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ゲノムと健康と長寿 ~遺伝で決まること、決まらないこと~
(八王子学園都市大学「いちょう塾」 2023)
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ヒトゲノムの解読困難領域の解析
(日本人類遺伝学会第67回大会 シンポジウム 2022)
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現代に受け継がれる古代人HLAハプロタイプ
(第76回 日本人類学会大会・ 第38回 日本霊⻑類学会大会 連合大会 シンポジウム 2022)
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Professional career (1):
Work history (4):
- 2022/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Life Science Professor
- 2015/02 - 2022/03 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences Faculty of Medicine Associate Professor
- 2010/11 - 2015/01 National Institute of Genetics Division of Human Genetics Assistant Professor
- 2005/04 - 2010/10 Tokai University School of Medicine Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine Post-doctoral fellow
Committee career (5):
- 2023 - 現在 日本人類遺伝学会 評議員
- 2023 - 現在 関東HLA研究会 評議員
- 2018 - 現在 日本赤十字社(造血幹細胞提供支援機関)HLA委員会 委員
- 2018 - 現在 日本骨髄バンク医療委員会主治医相談窓口 相談員
- 2016 - 現在 日本組織適合性学会 評議員
Awards (9):
- 2023/10 - 住友財団 環境研究助成(課題研究)
- 2023/09 - 公益財団法人 三菱財団 人文科学研究助成
- 2015/11 - 武田科学振興財団 医学系研究奨励
- 2014/11 - 臨床薬理研究振興財団 研究奨励金
- 2013/11 - 日本人類遺伝学会 最優秀ポスター賞
- 2011/11 - 武田科学振興財団 医学系研究奨励
- 2011/09 - 日本組織適合性学会 大会長賞
- 2009/09 - 日本組織適合性学会 学術奨励賞 最優秀賞
- 2000/03 - 大日本農会 大日本農会賞
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