Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (5)：
radiochemistry
, targeted alpha therapy
, radiopharmaceuticals
, nuclear medicine
, theranostics
Research theme for competitive and other funds (5)：
2021 - 2024 アルファ線を用いた切らない日帰りがん治療への挑戦
2020 - 2023 Targeted alpha therapy for patients with tumor
2019 - 2022 Development of Nuclear Medicine Therapy targeting Cancer Stroma
2018 - 2020 アミノ酸トランスポーターLAT1を標的とするα線がんミサイル療法の開発
2016 - 2019 生体内の細胞間コミュニケーション・イメージング用SPECT診断薬の創薬研究
Papers (56)：
Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Tadashi Watabe, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, Kenji Shirasaki, Hidetoshi Kikunaga, Kazuaki Tsukada, et al. Comparison of Nuclear Medicine Therapeutics Targeting PSMA among Alpha-Emitting Nuclides. International Journal of Molecular Sciences. 2024. 25. 2. 933-933
Atsushi Yagishita, Miho Katsuragawa, Shin’ichiro Takeda, Yoshifumi Shirakami, Kazuhiro Ooe, Atsushi Toyoshima, Tadayuki Takahashi, Tadashi Watabe. Development and Utility of an Imaging System for Internal Dosimetry of Astatine-211 in Mice. Bioengineering. 2023. 11. 1. 25-25
Ayaka Aso, Hinako Nabetani, Yoshifumi Matsuura, Yuichiro Kadonaga, Yoshifumi Shirakami, Tadashi Watabe, Taku Yoshiya, Masayoshi Mochizuki, Kazuhiro Ooe, Atsuko Kawakami, et al. Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine. International Journal of Molecular Sciences. 2023. 24. 10. 8701-8701
Iodine chemistry and applications
Wiley & Sons Inc 2014
Lectures and oral presentations (33)：
Synthesis and Preclinical Evaluation of 225Ac-PSMA-617 for Targeted Alpha Therapy in Mice with Prostate Cancer.
(IMR-Oarai & Oarai-Alpha Workshop 2022/09/28-30 2022)
