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J-GLOBAL ID：201601020979800333   Update date: Mar. 18, 2025

Nomoto Takahiro

ノモト タカヒロ | Nomoto Takahiro
Affiliation and department：
The University of Tokyo Graduate School of Arts and Sciences

About The University of Tokyo Graduate School of Arts and Sciences


Job title： Associate Professor
Homepage URL  (1)： https://sites.google.com/view/nomoto-lab/home
Research field  (3)： Tumor diagnostics and therapeutics ,  Biomaterials ,  Biomedical engineering
Research keywords  (3)： Neutron capture therapy ,  Photodynamic therapy ,  Drug delivery system
Research theme for competitive and other funds  (24)：
  • 2024 - 2028 ユニットPICを起点とする次世代核酸ナノ医薬の創製と生体内バリア突破に向けた挑戦
  • 2022 - 2028 代謝制御型薬物送達技術に基づく次世代医療モダリティの革新と創出
  • 2022 - 2026 Development of polymeric micelles based on innovative core-shell design for various therapeutic modalities
  • 2022 - 2025 Cold tumorをhot tumorに変える不安定鉄キレート技術の創出
  • 2021 - 2024 Transdermal drug delivery system of biomacromolecules by multiple ultrasonic irradiation
Show all
Papers (80)：
  • Yan Ming Voon, Haochen Guo, Kaito Kanamori, Tomoko Ogiyama, Hiroyuki Chaya, Koji Morita, Nobuhiro Nishiyama, Takahiro Nomoto. Effect of Spacers on the Affinity of Tyrosine-Modified Polymers to L-Type Amino Acid Transporter 1. Biomacromolecules. 2025
  • Yuto Honda, Shuhei Nagao, Hiroaki Kinoh, Xueying Liu, Nozomi Matsudaira, Anjaneyulu Dirisala, Shoko Nitta-Matsutomo, Takahiro Nomoto, Hiromi Hayashita-Kinoh, Yutaka Miura, et al. Adeno-Associated Virus Self-Assembled with Tannic Acid and Phenylboronic Acid Polymers to Evade Neutralizing Antibodies and Reduce Adverse Events. ACS Nano. 2025
  • Kakeru Konarita, Kaito Kanamori, Minoru Suzuki, Daiki Tokura, Shota Tanaka, Yuto Honda, Nobuhiro Nishiyama, Takahiro Nomoto. Poly(vinyl alcohol) potentiating an inert d-amino acid-based drug for boron neutron capture therapy. Journal of controlled release : official journal of the Controlled Release Society. 2025. 377. 385-396
  • Masahiro Toyoda, Yutaka Miura, Motoaki Kobayashi, Masato Tsuda, Takahiro Nomoto, Yuto Honda, Hiroyuki Nakamura, Hiroyasu Takemoto, Nobuhiro Nishiyama. Synthesis and Optimization of Ethylenediamine-Based Zwitterion on Polymer Side Chain for Recognizing Narrow Tumorous pH Windows. Biomacromolecules. 2024
  • Daiki Tokura, Kakeru Konarita, Minoru Suzuki, Keisuke Ogata, Yuto Honda, Yutaka Miura, Nobuhiro Nishiyama, Takahiro Nomoto. Active control of pharmacokinetics using light-responsive polymer-drug conjugates for boron neutron capture therapy. Journal of controlled release : official journal of the Controlled Release Society. 2024. 371. 445-454
ｍore...
MISC (144)：
  • 野本 貴大. 製剤技術 製剤と粒子設計 ホウ素中性子捕捉療法の適応拡大を目指した高分子型ドラッグデリバリーシステムの開発. PHARM TECH JAPAN. 2024. 40. 7. 1305-1308
  • 野本 貴大. 分子イメージング+臨床・治療 ホウ素中性子捕捉療法・光医療技術の応用範囲拡大を企図したドラッグデリバリーシステムの開発. JSMI Report. 2024. 17. 2. 49-49
  • 小成田翔, 小成田翔, 小成田翔, 登倉大貴, 登倉大貴, 登倉大貴, 鈴木実, 西山伸宏, 西山伸宏, 西山伸宏, et al. Poly(vinyl alcohol) improves therapeutic effectiveness of D-amino acid-based boron drug for neutron capture therapy. 日本薬学会年会要旨集(Web). 2024. 144th
  • 本田雄士, 本田雄士, 本田雄士, 松尾拓海, 松尾拓海, 野本貴大, 野本貴大, 西山伸宏, 西山伸宏, 西山伸宏. Systemic applicable Cas9-sgRNP RNP delivery systems based on polymeric ternary complexes for Cancer therapy. 日本薬学会年会要旨集(Web). 2024. 144th
  • 登倉大貴, 登倉大貴, 登倉大貴, 小成田翔, 小成田翔, 小成田翔, 鈴木実, 西山伸宏, 西山伸宏, 西山伸宏, et al. Development of drug delivery systems permitting active control of pharmacokinetics for boron neutron capture therapy. 日本薬学会年会要旨集(Web). 2024. 144th
ｍore...
Patents (28)：
ｍore...
Books (5)：
  • 月刊「化学」研究物語 スライムから発想を得たがん治療
    2020
  • 文藝春秋・巻頭随筆 液体のりとiPhone
    2020
  • ドラッグキャリア設計入門 DDSからナノマシンまで
    丸善出版 2019
  • Photochemistry for Biomedical Applications
    Springer Nature 2018
  • Cancer targeted drug delivery
    Springer 2013
Lectures and oral presentations  (141)：
  • 光薬物動態学に基づく新規ホウ素薬剤の開発
    (第20回日本中性子捕捉療法学会学術大会 2024)
  • Optopharmacokinetics using light-responsive polymer-drug conjugates for boron neutron capture therapy
    (2024)
  • AI-based optimization of physicochemical properties of polymer-drug conjugates for BNCT
    (20th International Congress on Neutron Capture Threapy 2024)
  • Design of biomaterials constituting drug delivery systems for boron neutron capture therapy
    (The 12th World Biomaterials Congress 2024)
  • ホウ素中性子捕捉療法・光医療技術の応用範囲拡大を企図したドラッグデリバリーシステムの開発
    (第18回日本分子イメージング学会総会・学術集会 2024)
ｍore...
Education (4)：
  • 2009 - 2014 The University of Tokyo School of Engineering Department of Bioengineering
  • 2007 - 2009 The University of Tokyo Department of Engineering Material Engineering
  • 2005 - 2007 The University of Tokyo College of Arts and Sciences
  • 2002 - 2005 私立早稲田高等学校
Work history (10)：
  • 2024/10 - 現在 Institute of Science Tokyo Institute of Integrated Research
  • 2024/04 - 現在 The University of Tokyo
  • 2023/04 - 現在 The University of Tokyo Graduate School of Arts and Sciences Associate Professor
  • 2023/04 - 2024/09 Tokyo Institute of Technology Institute of Innovative Research
  • 2016/04 - 2023/03 Tokyo Institute of Technology Institute of Innovative Research Assistant professor
Show all
Committee career (5)：
  • 2023 - 現在 日本光線力学学会 渉外委員会委員
  • 2023 - 現在 Photodiagnosis and Photodynamic Therapy Editorial Board Member
  • 2021/07 - 現在 日本中性子捕捉療法学会 薬剤評価標準化対応委員会 委員
  • 2021/07 - 現在 日本中性子捕捉療法学会 広報委員会 委員
  • 2022/11 - 2023/07 IPA 2023 organizing committee member
Awards (14)：
  • 2024 - 東京大学 令和6年度東京大学卓越研究員
  • 2023/03 - JST創発的研究支援事業 田中パネル第3回創発の場 Most Exciting Poster賞
  • 2021/09 - 19th International Congress on Neutron Capture Therapy Fairchild Award
  • 2021/08 - 東京工業大学科学技術創成研究院 IIRウィーク優秀発表賞
  • 2021/06 - 東京工業大学 挑戦的研究賞
Show all
Association Membership(s) (7)：
THE JAPANESE SOCIETY FOR BIOMATERIALS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本中性子捕捉療法学会 ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM ,  International Photodynamic Association ,  The Japan Photodynamic Association ,  The International Society for Neutron Capture Therapy
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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