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J-GLOBAL ID：201701009178051715   Update date: Mar. 17, 2025

Waki Toshiyuki

ワキ トシユキ | Waki Toshiyuki
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Affiliation and department：
Tohoku University Graduate School of Engineering Department of Biomolecular Engineering Applied Life Chemistry

About Tohoku University Graduate School of Engineering Department of Biomolecular Engineering Applied Life Chemistry


Job title： Assistant Professor
Homepage URL  (1)： http://www.che.tohoku.ac.jp/~seika/
Research field  (2)： Molecular biology ,  Applied molecular and cellular biology
Research keywords  (4)： カルコン合成酵素 ,  タンパク質間相互作用 ,  フラボノイド ,  植物特化代謝
Research theme for competitive and other funds  (4)：
  • 2023 - 2028 Molecular dissection of plant specialized metabolism machineries
  • 2022 - 2025 ダイズ細胞内のイソフラボン配糖体の分解代謝機構の解明
  • 2021 - 2024 フラボノイド生合成の細胞内動態を探る
  • 2020 - 2022 陸上植物に進化的に保存されたカルコン合成酵素の活性制御機構の解明
Papers (24)：
  • Seiji Takahashi, Miki Suenaga-Hiromori, Tomoki Ishii, Nadia Nur Shazana Binti Abu Talib Khan, Tomoyo Mikami, Tomohiro Takahashi, Chiho Minakawa, Fumihiro Yanbe, Toshiyuki Waki, Toru Nakayama, et al. Biosynthesis of unnatural polyisoprenes by engineered prenyltransferases on rubber particles. 2024
  • Kazuhiro Ohara, Yasuhiro Oshima, Hideaki Unno, Satoru Nagano, Masami Kusunoki, Seiji Takahashi, Toshiyuki Waki, Satoshi Yamashita, Toru Nakayama. Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family. Journal of bioscience and bioengineering. 2024
  • Toshiyuki Waki, Riki Imaizumi, Kaichi Uno, Yamato Doi, Misato Tsunashima, Sayumi Yamada, Ryo Mameda, Shun Nakata, Taro Yanai, Kohei Takeshita, et al. Structural insights into catalytic promiscuity of chalcone synthase from Glycine max (L.) Merr.: Coenzyme A-induced alteration of product specificity. Biochemical and Biophysical Research Communications. 2024. 150080-150080
  • Riki Imaizumi, Hiroaki Matsuura, Taro Yanai, Kohei Takeshita, Shuto Misawa, Haruhiko Yamaguchi, Naoki Sakai, Yukino Miyagi-Inoue, Miki Suenaga-Hiromori, Toshiyuki Waki, et al. Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. ChemBioChem. 2024
  • Taro Yanai, Yukino Takahashi, Eri Katsumura, Naoki Sakai, Kohei Takeshita, Riki Imaizumi, Hiroaki Matsuura, Shuntaro Hongo, Toshiyuki Waki, Seiji Takahashi, et al. Structural insights into a bacterial β-glucosidase capable of degrading sesaminol triglucoside to produce sesaminol: Toward the understanding of the aglycone recognition mechanism by the C-terminal lid domain. The Journal of Biochemistry. 2023. 174. 4. 335-344
ｍore...
MISC (53)：
  • 今泉璃城, 和氣駿之, 竹下浩平, 安田あおい, 松浦滉明, 中多舜, 坂井直樹, 片岡邦重, 高橋征司, 山本雅貴, et al. The Crystal Structure of Chalcone Synthase Complexd with Chalcone Isomerase-like Protein. 日本農芸化学会大会講演要旨集(Web). 2024. 2024
  • 和氣駿之. 多酵素複合体(メタボロン)によるフラボノイド代謝調節機構. 日本生薬学会年会講演要旨集. 2024. 70th
  • 和氣駿之, 垣生大希, 斎藤泰知, 古川楓, 高橋征司, 吉田久美, 中山亨. ダイズおよびキンギョソウにおけるアントシアニジン合成酵素の機能解析. 日本農芸化学会東北支部大会プログラム・講演要旨集. 2024. 159th (Web)
  • 矢内太朗, 高橋由季乃, 坂井直樹, 竹下浩平, 今泉璃城, 松浦滉明, 和氣駿之, 高橋征司, 山本雅貴, 片岡邦重, et al. The Crystal Structure of Sesame Lignan Glycoside Hydrolase and the Novel Function of its C-terminal Domain. 日本農芸化学会大会講演要旨集(Web). 2024. 2024
  • 和氣駿之. フラボノイド生合成を制御するメタボロン. 生物工学会誌. 2023. 101. 9. 493-496
ｍore...
Patents (2)：
Lectures and oral presentations  (12)：
  • A regulatory mechanism of flavonoid biosynthetic enzyme activity via protein-protein interaction
    (2023)
  • Inhibition mechanism of chalcone synthase by CoA-SH
    (2022)
  • Identification and functional characterization of enzyme involved in carthamin biosynthesis in safflower (Carthamus tinctorius L.)
    (2021)
  • フラボノイド生合成に進化的に保存されたカルコン合成酵素の活性制御機構とフラボノイドメタボロン
    (日本ビタミン学会第72回大会 2020)
  • Analysis of molecular mechanism involved in activation of chalcone synthase by means of Enhancer of Flavonoid Production
    (2019)
ｍore...
Professional career (1)：
  • 博士(工学) (Tohoku University)
Work history (1)：
  • 2016/10 - 現在 Tohoku University Graduate School of Engineering Department of Biomolecular Engineering
Awards (2)：
  • 2018/09 - 公益社団法人 日本農芸化学会 東北支部 2018年度 日本農芸化学会 東北支部 若手奨励賞 フラボノイド生合成における多酵素複合体(メタボロン)に関する研究
  • 2016/09 - The JSPCMB Student Award
Association Membership(s) (2)：
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  JAPANESE SOCIETY FOR PLANT CELL AND MOLECULAR BIOLOGY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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