Rchr
J-GLOBAL ID:201701009178051715   Update date: Sep. 27, 2022

Waki Toshiyuki

ワキ トシユキ | Waki Toshiyuki
Affiliation and department:
Job title: Assistant Professor
Homepage URL  (1): http://www.che.tohoku.ac.jp/~seika/
Research field  (2): Molecular biology ,  Applied molecular and cellular biology
Research keywords  (4): カルコン合成酵素 ,  タンパク質間相互作用 ,  フラボノイド ,  植物特化代謝
Research theme for competitive and other funds  (3):
  • 2022 - 2025 ダイズ細胞内のイソフラボン配糖体の分解代謝機構の解明
  • 2021 - 2024 フラボノイド生合成の細胞内動態を探る
  • 2020 - 2022 陸上植物に進化的に保存されたカルコン合成酵素の活性制御機構の解明
Papers (17):
  • Ryo Kutsukawa, Riki Imaizumi, Miki Suenaga-Hiromori, Kohei Takeshita, Naoki Sakai, Shuto Misawa, Masaki Yamamoto, Haruhiko Yamaguchi, Yukino Miyagi-Inoue, Toshiyuki Waki, et al. Structure-based engineering of a short-chain cis -prenyltransferase to biosynthesize nonnatural all- cis -polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain-length determination. The FEBS Journal. 2022
  • Daiki Oikawa, Satoshi Yamashita, Seiji Takahashi, Toshiyuki Waki, Koichi Kikuchi, Takaaki Abe, Takane Katayama, Toru Nakayama. (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis. Biochemical and biophysical research communications. 2022. 590. 158-162
  • Toshiyuki Waki, Miho Terashita, Naoki Fujita, Keishi Fukuda, Mikiya Kato, Takashi Negishi, Hiromi Uchida, Yuichi Aoki, Seiji Takahashi, Toru Nakayama. Identification of the Genes Coding for Carthamin Synthase, Peroxidase Homologs that Catalyze the Final Enzymatic Step of Red Pigmentation in Safflower (Carthamus tinctorius L.). Plant & cell physiology. 2021
  • Toshiyuki Waki, Seiji Takahashi, Toru Nakayama. Managing enzyme promiscuity in plant specialized metabolism: A lesson from flavonoid biosynthesis: Mission of a "body double" protein clarified. BioEssays : news and reviews in molecular, cellular and developmental biology. 2021. 43. 3. e2000164
  • Hideo Ohira, Atsuki Tsuruya, Daiki Oikawa, Wao Nakagawa, Rie Mamoto, Masahira Hattori, Toshiyuki Waki, Seiji Takahashi, Yoshio Fujioka, Toru Nakayama. Alteration of oxidative-stress and related marker levels in mouse colonic tissues and fecal microbiota structures with chronic ethanol administration: Implications for the pathogenesis of ethanol-related colorectal cancer. PloS one. 2021. 16. 2. e0246580
more...
MISC (32):
  • 和氣 駿之. フラボノイド生合成における縁の下の力持ち. 生物工学会誌. 2022. 100. 5. 254-254
  • 天野博之, 栗栖尚嗣, 山家史大, 廣森美樹, 和氣駿之, 中山亨, 高橋征司. Elucidation of molecular mechanisms for product specificity of terpene synthases by comparative functional analyses. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
  • NUR SHAZANA BINTI ABU TALIB KHAN Nadia, 廣森美樹, 和氣駿之, 山下哲, 戸澤譲, 山口晴彦, 宮城ゆき乃, 中山亨, 高橋征司. Identification and functional analysis of interaction domains of rubber transferase protein complex from Hevea brasiliensis. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
  • 高橋朋宏, 山家史大, 酒井勇貴, 皆川知歩, 和氣駿之, 中山亨, 高橋征司. Phosphorylation-mediated regulation of eukaryotic cis-prenyltransferases contributing to dolichol biosynthesis. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
  • Nakayama Toru, Waki Toshiyuki, Takahashi Seiji. Metabolon formation in plant specialized metabolism. Regulation of Plant Growth & Development. 2021. 56. 1. 14-25
more...
Patents (1):
Lectures and oral presentations  (11):
  • Inhibition mechanism of chalcone synthase by CoA-SH
    (2022)
  • Identification and functional characterization of enzyme involved in carthamin biosynthesis in safflower (Carthamus tinctorius L.)
    (2021)
  • フラボノイド生合成に進化的に保存されたカルコン合成酵素の活性制御機構とフラボノイドメタボロン
    (日本ビタミン学会第72回大会 2020)
  • Analysis of molecular mechanism involved in activation of chalcone synthase by means of Enhancer of Flavonoid Production
    (2019)
  • Enhancer of Flavonoid Productionによるカルコン合成酵素の生成物特異性制御
    (日本農芸化学会東北・北海道合同支部大会 2018)
more...
Professional career (1):
  • 博士(工学) (Tohoku University)
Work history (1):
  • 2016/10 - 現在 Tohoku University Graduate School of Engineering Department of Biomolecular Engineering
Awards (2):
  • 2018/09 - 公益社団法人 日本農芸化学会 東北支部 2018年度 日本農芸化学会 東北支部 若手奨励賞 フラボノイド生合成における多酵素複合体(メタボロン)に関する研究
  • 2016/09 - The JSPCMB Student Award
Association Membership(s) (2):
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  JAPANESE SOCIETY FOR PLANT CELL AND MOLECULAR BIOLOGY
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